A Stochastic View of Spliceosome Assembly and Recycling in the Nucleus by José Rino (81063)

“…Inhibition of splicing, which reduces the number of pre-mRNA binding sites available for spliceosome assembly, was modeled as a decrease in the on-rate binding constant in the nucleoplasm. …”

Population-level hysteresis as a function of average density . by Chad M. Topaz (141835)

“…As passes through the point of linear instability (marked with an asterisk) the solution jumps up to the green curve, which represents compactly supported gregarious aggregations obtained via numerical simulation, similar to the final states of <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002642#pcbi-1002642-g004" target="_blank">Fig. 4</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002642#pcbi-1002642-g005" target="_blank">Fig. 5</a>. …”

The effect of meal frequency in a reduced-energy regimen on the gastrointestinal and appetite hormones in patients with type 2 diabetes: A randomised crossover study by Lenka Belinova (618839)

“…Fasting ghrelin decreased in A6 and increased in B2 (with difference between regimens <i>p</i> = 0.023). …”

Supplementary Material for: Association between a Lumican Promoter Polymorphism and High Myopia in the Chinese Population: A Meta-Analysis of Case-Control Studies by Deng Z.-J. (4143013)

“…<b><i>Results:</i></b> This meta-analysis, including 1,545 subjects from 5 studies, indicated that Chinese lumican rs3759223 C allele carriers had a decreased risk of high myopia in comparison to T allele carriers (odds ratio: 0.531; 95% confidence interval, CI: 0.304-0.925; p = 0.025). …”

Aurora A Inhibitor I promotes changes in phosphorylation of Aurora kinases and induction of apoptosis in leukemia cell lines in a time dependent manner. by Aarthi Jayanthan (601947)

“…Western blot analysis indicates a slight increase in phosphorylation of Aurora-A at 12 and 24 hours for C1 and an initial decrease, followed by a subsequent increase in phosphorylation of Aurora-A starting at 4 hours for KOPN8 and 6 hours for both SEM and TIB-202. …”

let-7a blocks ESFT tumor growth. by Claudio De Vito (210326)

“…<b>B</b>) MTT proliferation assay of mock-infected and let-7a-overexpressing A673 and TC252 cells. <b>C</b>) let-7a overexpression in A673 (left panel) and TC252 (right panel) tumor cells leads to a significant decrease in their tumorigenicity. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…We found that freezing converts long supramolecular nanofibers into shorter ones, compromising their ability to support cell adhesion, but a single heating and cooling cycle reverses the damage and rescues their bioactivity. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…We found that freezing converts long supramolecular nanofibers into shorter ones, compromising their ability to support cell adhesion, but a single heating and cooling cycle reverses the damage and rescues their bioactivity. …”

A New Murine Model for Gastrointestinal Anthrax Infection by Tao Xie (146080)

“…Time-course experiments revealed early compromise of the intestinal epithelium, characterized by villus blunting and ulceration in the ileum and jejunum. A decrease in body temperature was most predictive of near-term lethality. …”

Cell motility depends on a QSF secreted by cells. by Laurent Golé (198154)

“…<p>The diffusion coefficient is decreasing with cell density and experimental time, highlighting the role played by a QSF factors in cell motion. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…We found that freezing converts long supramolecular nanofibers into shorter ones, compromising their ability to support cell adhesion, but a single heating and cooling cycle reverses the damage and rescues their bioactivity. …”

Directed Growth of Orthorhombic Crystals in a Micropillar Array by Gregor Holzner (3707893)

“…Crystal growth near the region of interest resulted in a sharp decrease in the local solute concentration (which rapidly returns the concentration to the solubility limit), consistent with estimated diffusion time scales (<1 s for a 50 μm length scale). …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…We found that freezing converts long supramolecular nanofibers into shorter ones, compromising their ability to support cell adhesion, but a single heating and cooling cycle reverses the damage and rescues their bioactivity. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…We found that freezing converts long supramolecular nanofibers into shorter ones, compromising their ability to support cell adhesion, but a single heating and cooling cycle reverses the damage and rescues their bioactivity. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…We found that freezing converts long supramolecular nanofibers into shorter ones, compromising their ability to support cell adhesion, but a single heating and cooling cycle reverses the damage and rescues their bioactivity. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…We found that freezing converts long supramolecular nanofibers into shorter ones, compromising their ability to support cell adhesion, but a single heating and cooling cycle reverses the damage and rescues their bioactivity. …”

Self-Repair of Structure and Bioactivity in a Supramolecular Nanostructure by Charlotte H. Chen (5915282)

“…We found that freezing converts long supramolecular nanofibers into shorter ones, compromising their ability to support cell adhesion, but a single heating and cooling cycle reverses the damage and rescues their bioactivity. …”

Mechanism of MurA inhibition by UNAG-3P. by Hannes Mutschler (226962)

“…MurA enzyme kinetics were followed by coupling the reaction to phosphate-dependent cleavage of fluorescent 7-methylguanosine by nucleoside phosphorylase, resulting in a decrease in fluorescence at 400 nm (λ_exc = 300 nm). …”

A dominant gene is upregulated in CSA binding parasites by Stuart A Ralph (12744)

“…Only statistically differential data giving a Bonferroni corrected value (alpha = 0.05) have been displayed. …”

A 48-year-old man with Moyamoya disease. by Soo Buem Cho (4576561)

“…(F). On a spectral plot from a MonoE image at 40 keV, active extravasation reveals a gradual decrease in HU values with a steep slope (ROI 3), suggesting iodine. …”