<i>Ufm1</i>, <i>Ufbp1</i>and <i>Ufl1</i> expressionis induced upon ER stress. by Katleen Lemaire (225733)

“…<p>A mRNA expression level of <i>Ufm1</i> (A), <i>Ufbp1</i>(B) or <i>Ufl1</i> (C) after exposure of INS-1E cells to 25 µM CPA, 1 µM thapsigargin, 1 µg/ml brefeldin A, 5 µg/ml cycloheximide, 30 µM H₂O₂, 0.5 mMoleate and 0.5 mMpalmitate for 14 hours, measured via qPCR and normalized for GAPDH (<i>Ufm1</i> and <i>Ufbp1</i>) or actin (<i>Ufl1</i>). …”

Rapamycin pretreatment attenuated the neuroprotective effects of TAT-14-3-3ε. by Yuanjun Zhu (412079)

“…<p>Rats were treated with a single i.c.v. injection of saline or 600-MA at the onset of reperfusion, or RAP (35 pmol, i.c.v.) combined with TAT-14-3-3ε (10 mg/kg, i.v.) 2 h before ischemia, and then followed by 24 h reperfusion. …”

Temporal distribution of <i>P</i>. <i>vivax</i> malaria episodes and immune response targeting region II of the Duffy binding protein (DBPII), Rio Pardo Settlement, Amazonas, Brazi... by Flora S. Kano (548431)

“…(<b>C</b>) DBPII binding inhibitory antibodies (BIAbs) had a slightly decreased frequency at the 12 months follow-up examination. …”

KLF4 was absent and inhibited the proliferation in ccRCC cell lines. by Erlin Song (431220)

“…<p>(A) KLF4 expression in normal renal proximal tubular epithelial cell line HKC and ccRCC cell lines. …”

Extended Use of the Control-IQ Closed-Loop Control System in Children With Type 1 Diabetes by Lauren G. Kanapka (8166714)

“…<b></b> <p><b>Research Design and Methods: </b>Following a 16-week randomized clinical trial (RCT) comparing CLC with sensor augmented pump (SAP) therapy in 101 children age 6 to 13 years old with type 1 diabetes, 22 participants in the SAP group initiated use of the CLC system (referred to as SAP-CLC cohort), and 78 participants in the CLC group continued use of CLC (CLC-CLC cohort) for 12 weeks. …”

Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R... by Mei-yan Wu (9921201)

“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i>_latent) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i>_burst) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i>_latent and Δ<i>T</i>_burst times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i>_latent time. …”

Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R... by Mei-yan Wu (9921201)

“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i>_latent) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i>_burst) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i>_latent and Δ<i>T</i>_burst times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i>_latent time. …”

Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R... by Mei-yan Wu (9921201)

“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i>_latent) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i>_burst) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i>_latent and Δ<i>T</i>_burst times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i>_latent time. …”

Integrity of AWC cilia structure is critical for proper localization of EGL-4. by Damien M. O'Halloran (185919)

“…Calcium levels in AWC have been shown to decrease after ligand binding <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000761#pgen.1000761-Chalasani1" target="_blank">[13]</a>. …”

Reversal of ROS induced autophagic vacuole formation in F-HABP07 upon polymeric HA supplementation. by Paramita Saha (473954)

“…<p>[<b>A to D</b>] <b><i>Polymeric </i><i>HA </i><i>supplementation </i><i>restores </i><i>cellular </i><i>homeostasis </i><i>in </i><i>F-HABP07 </i><i>cells</i></b>-- As a result of significant reduction in ROS generation as evident from the decreased fluorescence intensity upon H₂DCFDA treatment (<b>A</b> and <b>B</b>); about 25% revival of growth was observed in F-HABP07 cells (<b>C</b>). …”

Proof of Concept, Randomized, Placebo-Controlled Study of the Effect of Simvastatin on the Course of Age-Related Macular Degeneration by Robyn H. Guymer (168403)

“…<i>Intent to treat</i> multivariable logistic regression analysis, adjusted for age, sex, smoking and baseline AMD severity, showed a significant 2-fold decrease in the risk of progression in the simvastatin group: OR 0.43 (0.18–0.99), p = 0.047. …”

Data_Sheet_1_Coordinated Reset Vibrotactile Stimulation Induces Sustained Cumulative Benefits in Parkinson’s Disease.pdf by Kristina J. Pfeifer (10095703)

“…EEG recordings observed from study 1 indicated a significant decrease in off-medication cortical sensorimotor high beta power (21—30 Hz) at rest after 3 months of daily noisy vCR therapy. …”

Image_1_Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis.TIF by Jacob Amersfoort (6075341)

“…Taken together, T cell-specific deficiency of Atg7 resulted in a decrease in hepatic steatosis and limited inflammatory potency in the (naïve) T cell compartment in peripheral lymphoid tissues, which was associated with a strong reduction in experimental atherosclerosis.…”

Absence of LAMP5 disrupts olfaction and leads to anxiety-like behavior. by Marie-Catherine Tiveron (272288)

“…Habituation occurs similarly for both WT and KO mice as shown by a significant decrease in investigation time between the first (Oh1) and last (Oh4) trials (*, p<0.05; **, p<0.01; ***, p<0.001). …”

Progressive differences between IPCs and OC surface proportions promoted 2° and 3° formation. by David E. Larson (246516)

“…‘No OC Expansion’, No Death' curve indicates constant OC surface area (no expansion) and no cell death. (<b>C</b>) A graph indicating the decrease in cell number for the different simulations. …”

<i>NDUFS7</i> depletion in motor neurons affects synapse stability. by Bhagaban Mallik (12459375)

“…The motor neuron-depleted <i>NDUFS7[RNAi]</i> larvae showed a decrease in the number of Futsch-positive loops as compared to the Gal4 control. …”

Defect Tolerance to Intolerance in the Vacancy-Ordered Double Perovskite Semiconductors Cs₂SnI₆ and Cs₂TeI₆ by Annalise E. Maughan (1694959)

“…However, even though tellurium substitution increases electronic dispersion via closer I–I contact distances, the substitution experimentally yields insulating behavior from a significant decrease in carrier concentration and mobility. …”

Pi across filarial nematode species and model organisms. by John Mattick (544773)

“…<i>melanogaster</i> also has a decrease in Pi; it is a small chromosome sometimes referred to as the dot chromosome that is largely heterochromatic and may formerly have been a sex chromosome [<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0009838#pntd.0009838.ref074" target="_blank">74</a>].…”

Defect Tolerance to Intolerance in the Vacancy-Ordered Double Perovskite Semiconductors Cs₂SnI₆ and Cs₂TeI₆ by Annalise E. Maughan (1694959)

“…However, even though tellurium substitution increases electronic dispersion via closer I–I contact distances, the substitution experimentally yields insulating behavior from a significant decrease in carrier concentration and mobility. …”

Prediction performance of each model. by Ahmed S. Alkhalifah (20721713)

“…Further studies to define a safe upper limit for IBW-adjusted MP may help clinicians optimize mechanical ventilation settings and decrease the risk of VILI and mortality.…”