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ht decrease » _ decrease (Expand Search), a decrease (Expand Search), we decrease (Expand Search)
50 ns » 50 ms (Expand Search)
5 ht » 5 h (Expand Search)
ppm decrease » _ decrease (Expand Search), a decrease (Expand Search), pa decreased (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
ns decrease » _ decrease (Expand Search), a decrease (Expand Search), we decrease (Expand Search)
ht decrease » _ decrease (Expand Search), a decrease (Expand Search), we decrease (Expand Search)
50 ns » 50 ms (Expand Search)
5 ht » 5 h (Expand Search)
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Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs
Published 2022“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs
Published 2022“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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Additional Analysis of visually induced calcium transients in Fig 6.
Published 2020“…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …”