Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2. by Thirumal Kumar, D

“…In the case of D2HGDH protein, the mutations I147S and V444A that are positioned in the beta sheet region exhibited higher Root Mean Square Deviation (RMSD), decrease in compactness and number of intramolecular hydrogen bonds compared to the mutations N439D and D375Y that are positioned in the turn and loop region, respectively. …”
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Development of Internally Pressurized Composite/Metallic/Composite Hybrid Pipes by Alabtah, Fatima Ghassan

“…The testing results showed significant improvement in the internal pressure capacity compared to the conventional steel pipes. Fourth, a detailed evaluation of fiber type’s effect on the electrochemical corrosion aspects in different highly corrosive solutions, 0.5 M NaCl, 0.5 M HCl, and 0.5 M H2SO4, was presented. …”
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Thermally conductive polyethylene/expanded graphite composites as heat transfer surface: Mechanical, thermo-physical and surface behavior by Sobolčiak, Patrik

“…This enhanced surface wettability was retained over a long time with only a 9% and 18% decrease in RF and corona plasma-treated samples' surface energy after two months. …”
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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte. by Marei, Hany E

“…The differentiation medium, containing cAMP, PDGFA, T3, and all-trans-retinoic acid (ATRA), promotes OBNSCs to generate mostly oligodendrocytes (OLs) displaying morphological changes, and appearance of long cytoplasmic processes. OBNSCs showed, after 5 days in OLs differentiation medium, a considerable decrease in the number of nestin positive cells, which was associated with a concomitant increase of NG2 immunoreactive cells and few O4(+)-OPCs. …”
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS by ELJILANY, ISLAM AHMED SAYED AHMED

“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-analysis of Safety and Efficacy by Yi F.

“…BACKGROUND: Radiofrequency ablation (RFA) and antiarrhythmic drugs (AADs) are the main treatments used for atrial fibrillation (AF). In recent years, a number of articles comparing the 2 treatments have begun to emerge. …”
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EPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS by ABU-EL-RUZ, RASHA

“…We conducted random-effects meta-regressions to identify sources of heterogeneity and possible predictors of high prevalence. Results: The pooled-mean urogenital CT prevalence was 8.2% (95% CI: 7.5-9.1) for general populations, 14.0% (95%CI: 12.7-15.4) for female sex workers, 10.8% (95% CI: 8.4-13.4) for men who have sex with men, male sex workers, and transgenders, 16.1% (95% CI: 12.6-19.8) for symptomatic women, 25.4 (95% CI: 18.6-38.5) for symptomatic men, 9.7% (95%CI: 6.1-14) for HIV-positive individuals and individuals in HIV-discordant couples, and 11.9% (95 CI: 8.5-15.8) for STI clinic attendees. …”
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Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus by Dimitrios, Patoulias

“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
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Mechanical and microstructure characterization of hard nanostructured N-bearing thin coating by Cabibbo, M.

“…The main problem with steel, is that it exhibits a relatively low hardness (below 10GPa) which strongly decreases upon annealing above about 600K. …”
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Assessment of Urban Heat Islands Based on the Relationship Between Land Surface Temperature and Land Use/Land Cover in Greater Doha by Siddiqui, Simil Amir

“…Furthermore %LULC of built up, vegetation, barren land, marsh land and water body were 29%, 4.5%, 58.6%, 2.8% and 5% in 2000 and 56.5 %, 8.2%, 33.2 %, 0% and 2.1% in 2019 respectively. …”
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Structural and electrochemical properties of electrodeposited Ni-P nanocomposite coatings containing mixed ceramic oxide particles by Zadeh, K.M.

“…The coatings were electrodeposited on mild steel substrate and were then characterized using various techniques. …”
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Inter-annual variability and distribution of aerosols during winters and aerosol optical thickness over Northeastern Pakistan by Shahid, M. Z.

“…ir pollution during winters over north-eastern (NE) Pakistan (71–74.5 E, 28–34 N) is a major challenge that affects human health, climate and daily life. …”
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Heat stress impairs proprioception but not running mechanics by Mtibaa K.

“…Methods 12 trained runners performed a proprioception test (active movement discrimination) before and immediately after a 30 min, self-paced treadmill run in HOT (39 °C) and COOL (22 °C) ambient conditions. …”
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High temperature thermal stability of innovative nanostructured thin coatings for advanced tooling by Cabibbo, Marcello

“…The main problem with steel, isthat itexhibits a relatively low hardness (below 10 GPa) which strongly decreases upon annealing above about 600 K.Thus, the majority of modern tools are nowadays coated with hard coatings that increase the hardness, decrease the coefficient of friction and protect the tools against oxidation. …”
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Influence of anionic surface modifiers on the thermal stability and mechanical properties of layered double hydroxide/polypropylene nanocomposites by Yang, J.H.

“…Organo-layered double hydroxide/polypropylene (LDH/PP) nanocomposites were successfully synthesized via a solution blending method. As an attempt to improve the compatibility with hydrophobic PP, the LDH surface was modified by the incorporation of various anionic surfactants via electrostatic interaction with LDH cationic layers. …”
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Overconfident results with the bivariate random effects model for meta-analysis of diagnostic accuracy studies by Furuya-Kanamori, Luis

“…Diaz found that the performance of the bivariate model deteriorates when between-study heterogeneity increases and the number of studies decrease.5 Our simulation studies found similar results—with moderate levels of heterogeneity (tau2 = 1), the coverage probabilities of Se, Sp, and the diagnostic odds ratio (DOR) with the bivariate model dropped below the nominal level.6 Diagnostic accuracy studies usually favor sensitivity over specificity, or vice versa leading to diagnostic 2 × 2 tables with one or more of the cells with low frequency or zero counts. …”
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Effect of concentration of DOC loaded TiO 2 nanotubes on the corrosion behavior of smart coatings by Ubaid F.

“…Various contents of the encapsulated TiO2 nanotubes (1, 3 and 5 wt%) were thoroughly dispersed into the epoxy matrix and the resulting composites were then applied on a cleaned steel substrate using doctor blade technique to develop smart coatings. …”
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Recycled Concrete Used in Subbase in Potential Use for Road Base and Cement Bounded Material (CBM) by Ahmad, Hassan Haidar

“…This paper will focus on the fine recycled concrete (FRC) 0-5 mm as a fine aggregate material in the mix design for constructing the base road layers under the Asphalt layers and how using crushed concrete can increase the quality and change the classification of the base aggregate mixes. …”
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Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy by Shawaqfah M.

“…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. …”
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Pd nanocrystals encapsulated in MOF-derived Ni/N-doped hollow carbon nanosheets for efficient thermal CO oxidation: unveiling the effect of porosity by Ipadeola, Adewale K.

“…This is evidenced in the great ability of Pd/Ni-MOF-HNC to utterly oxidize CO at a lower complete conversion temperature (T100) of 114.5 °C compared with Pd/Ni-MOF-NC (153.8 °C) and Pd/C (201.5 °C) under atmospheric pressure. …”
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