Preparation and Characterization of Homologous Diiron Dithiolato, Diselenato, and Ditellurato Complexes: [FeFe]-Hydrogenase Models by Mohammad K. Harb (2331892)

“…Treatment of Fe₃(CO)₁₂ with 3,3-bis(thiocyanatomethyl)oxetane (<b>1</b>) or a mixture of 2-oxa-6,7-dithiaspiro[3.4]octane (<b>2a</b>) and 2-oxa-6,7,8-trithiaspiro[3.5]nonane (<b>2b</b>) in toluene at reflux afforded the model compound Fe₂(μ-S₂C₅H₈O)(CO)₆ (<b>3</b>). …”

Data_Sheet_2_Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.docx by Bih-Rong Wei (369553)

“…Animals were monitored for PK following single dose and 17-day repeat dosing, and by clinical observations, hematology, serum biochemistry, coagulation studies and urinalyses. A single trametinib dose (0.025 mg/kg), sulfated as dimethyl sulfoxide which enhanced its absorption, reached mean maximum concentration (C_max) 0.64 ng/mL [18% coefficient of variation (CV)] at a median time to maximum concentration (T_max) of 1.5 h (hr), and mean area under the concentration-time curve (AUC) 16.8 hr^*ng/mL (14%CV), which were similar when given alone or in combination with sapanisertib. …”

Data_Sheet_1_Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs.docx by Bih-Rong Wei (369553)

“…Animals were monitored for PK following single dose and 17-day repeat dosing, and by clinical observations, hematology, serum biochemistry, coagulation studies and urinalyses. A single trametinib dose (0.025 mg/kg), sulfated as dimethyl sulfoxide which enhanced its absorption, reached mean maximum concentration (C_max) 0.64 ng/mL [18% coefficient of variation (CV)] at a median time to maximum concentration (T_max) of 1.5 h (hr), and mean area under the concentration-time curve (AUC) 16.8 hr^*ng/mL (14%CV), which were similar when given alone or in combination with sapanisertib. …”

Spatial and temporal coordination of traction forces in one-dimensional cell migration by Sangyoon J. Han (2936559)

Image_1_Fluctuations in emergency department visits related to acute otitis media are associated with extreme meteorological conditions.pdf by Michael Nieratschker (14765098)

“…Prolonged extreme weather conditions over three days, however, significantly increased the cRR for AOM-related EVs to 3.15 [1.26–7.88; p = 0.014] and 2.14 [1.14–4.04; p = 0.018] at mean temperatures of −4°C (1^st-percentile - p₁) and 0°C (p₅) on the same day. …”

Table_1_Fluctuations in emergency department visits related to acute otitis media are associated with extreme meteorological conditions.docx by Michael Nieratschker (14765098)

“…Prolonged extreme weather conditions over three days, however, significantly increased the cRR for AOM-related EVs to 3.15 [1.26–7.88; p = 0.014] and 2.14 [1.14–4.04; p = 0.018] at mean temperatures of −4°C (1^st-percentile - p₁) and 0°C (p₅) on the same day. …”

Analysis of dopant diffusion in molten germanium induced by pulsed nd : yag laser by Mousa, Ali M. [علي مطشر موسى]

“…Doped sample Tann = 200- 500 C for time t mn = 45 subjected to subsequent thermal annealing (at the temperature and to plused leacr annealing (en<5rgy density in a min) pluse E=5.2 - 9.5 J/cm2) in order to establish optimal condition. …”
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DataSheet_1_An integrative multi-omic analysis defines gut microbiota, mycobiota, and metabolic fingerprints in ulcerative colitis patients.docx by Matteo Scanu (13197234)

“…</p>Results<p>In the UC cohort, we reported the increase of Streptococcus, Bifidobacterium, Enterobacteriaceae, TM7-3, Granulicatella, Peptostreptococcus, Lactobacillus, Veillonella, Enterococcus, Peptoniphilus, Gemellaceae, and phenylethyl alcohol; and we also reported the decrease of Akkermansia; Ruminococcaceae; Ruminococcus; Gemmiger; Methanobrevibacter; Oscillospira; Coprococus; Christensenellaceae; Clavispora; Vishniacozyma; Quambalaria; hexadecane; cyclopentadecane; 5-hepten-2-ol, 6 methyl; 3-carene; caryophyllene; p-Cresol; 2-butenal; indole, 3-methyl-; 6-methyl-3,5-heptadiene-2-one; 5-octadecene; and 5-hepten-2-one, 6 methyl. …”

LGR4 is required for RSPO1-induced Wnt/β-catenin signaling. by Heinz Ruffner (150990)

“…(b) Expression of LGR4, LGR5 and LGR6 rescue LGR4 siRNA-elicited decrease in RSPO1-induced STF reporter activation. …”

Table_1_The Extent of Alcohol-Related Problems Among College and University Students in Norway Prior to and During the COVID-19 Pandemic.DOCX by Ove Heradstveit (10307177)

“…</p>Findings<p>37.0% of male students and 24.1% of female students reported either risky, harmful, or dependent alcohol use in 2021, compared with 55.0% of male students and 43.6% of female students in 2018. This decrease in alcohol-related problems was most pronounced for dependent alcohol use, where we observed a 57% relative reduction among male students (from 3.5% in 2018 to 1.5% in 2021) and a 64% relative reduction among female students (from 1.4% in 2018 to 0.5% in 2021).…”

Effect of positive end-expiratory pressure (PEEP) on left ventricular (LV) filling by Thomas Luecke (62130)

data.zip by Dapang Rao (11031348)

“…</a> In addition, INPP4B、HPGD、IGFBP5 and IL1R2 genes were upregulated, and PRKACB、TMSB4X and CCND1 downregulated in DOCK1 knockout cells. …”

Proteomic profiling of vocal fold and co-cultivated construct samples. by Tanja Grossmann (6458798)

“…Proteins are sorted in a decreasing manner according to their mean LFQ intensity values (A,C). …”

Loss of <i>bmm</i> in the somatic cells of the gonad with an independent RNAi line has no effect on triglyceride storage or breakdown in females. by Lianna W. Wat (8339454)

“…(F) Triglyceride breakdown post-starvation among 5-day-old virgin <i>c587>UAS-bmm;UAS-bmm-RNAi</i> females and control females (<i>c587</i>>+ and <i>+>UAS-bmm;UAS-bmm-RNAi</i>) showed a modest decrease of a similar magnitude at both 0–12 hours or 12–24 hours STV (<i>p</i> = 0.0043, 1.7 × 10⁻⁶, and 0.0027 for 0–12 hours and 0.0, 2.6 × 10⁻⁶, and 2.9 × 10⁻⁴ for 12–24 hours, respectively; one-way ANOVA followed by Tukey HSD test). …”

All used data in this study. by Shiva Gharibi (18857929)

“…Individual trees, strip trees, abandoned lands, parks, and gardens led to a decrease in traffic noise by 0.3, 1, 0.1, 3.5, and 4.5 dB, respectively. …”

Image 2_Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.jpeg by Peng Chen (6514)

“…</p>Results<p>MR analysis revealed that a decrease of one standard deviation (SD) in plasma R-Spondin 3 (RSPO3) level had a protective effect on EM (OR = 1.0029; 95% confidence interval (95% CI): 1.0015–1.0043; P = 3.2567e-05; Bonferroni P < 5.63 × 10⁻⁵). …”

MeCP2 overexpression leads to eye, wing and motor performance phenotypes. by Holly N. Cukier (201950)

“…<p>Light microscope images (A–E), and scanning electron microscope images (A'–D”) of fly eyes from controls or animals expressing MeCP2 driven by <i>GMR-Gal4</i> driver at either 27.5°C or 30°C. …”

Table 1_Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.xlsx by Peng Chen (6514)

“…</p>Results<p>MR analysis revealed that a decrease of one standard deviation (SD) in plasma R-Spondin 3 (RSPO3) level had a protective effect on EM (OR = 1.0029; 95% confidence interval (95% CI): 1.0015–1.0043; P = 3.2567e-05; Bonferroni P < 5.63 × 10⁻⁵). …”

Image 1_Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.jpeg by Peng Chen (6514)

“…</p>Results<p>MR analysis revealed that a decrease of one standard deviation (SD) in plasma R-Spondin 3 (RSPO3) level had a protective effect on EM (OR = 1.0029; 95% confidence interval (95% CI): 1.0015–1.0043; P = 3.2567e-05; Bonferroni P < 5.63 × 10⁻⁵). …”

Reproducibility and sensitivity of the method by Axel Schumacher (13710)

“…The decrease of amount of DNA is reflected in the angle of the regression lines, which deviated by 5–7% from the expected values.…”