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26461
PRSS56 activity is required during both the vision-independent and dependent stages of ocular growth.
Published 2018“…Reduced ocular axial length was associated with a significant decrease in VCD in <i>Prss56</i><sup><i>F/F</i></sup><i>; Ubc-Cre</i><sup><i>ERT2</i></sup> mice compared to <i>Prss56</i><sup><i>F/+</i></sup><i>; Ubc-Cre</i><sup><i>ERT2</i></sup> and uninjected controls at P30 and P45, N = 5 to 10 per group (<b>G</b>). …”
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26462
S1 Fig - Rescue of Retinal Function by BDNF in a Mouse Model of Glaucoma
Published 2014“…At the age of 11 months RGCs expressing γ-Synuclein were significantly reduced in the peripheral retina (n mice = 3, 6 eyes; mean in the central retina = 7451.87, SEM = 136.39; mean in the peripheral retina = 5892.74, SEM = 232.35) while at later ages both the central and peripheral retina resulted affected (14 months of age n mice = 3, eyes 6, mean cell density in central retina = 4866, SEM = 261.27; mean cell density in peripheral retina = 4682, SEM = 366.13; 17 months, n mice = 3, eyes = 5; mean cell density in central retina = 3634.66, SEM = 632.77; mean cell density in peripheral retina = 3632, SEM = 287.21). …”
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26463
MOESM2 of The Study of Enhanced High-Intensity Focused Ultrasound Therapy by Sonodynamic N2O Microbubbles
Published 2019“…(The data were shown as mean ± SD, n = 5 per group, *p < 0.05). To Select the optimal time for ultrasound, MDA-MB-231 cells were seeded in a 96-well plate at a density of 5000 cells per well for 24 h. …”
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26464
Combined Analysis DataFilter_Script for experiment 1 & 2
Published 2020“…The sample size for wild type controls treated with PBS (WT-PBS, n=6), wild type treated with DEX (WT-DEX, n=6), MKO treated with PBS (MKO-PBS, n=5) and MKO treated with DEX (MKO-DEX, n=5). The rational for biological replicates of n=5-6 were used to ensure accurate comparison among each group. …”
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26465
Sagittal Balance Parameters and Proximal Junctional Kyphosis in Adolescent Idiopathic Scoliosis: Dataset and Results.
Published 2024“…Moreover, a decreased rod contour angle (RCA) (test for overall effect Z = 3.79, p < 0.0002) and higher proximal junctional angle–rod contour angle (PJA-RCA) (test for overall effect Z = 39.18, p < 0.00001) play a significant role in the risk of developing PJK after AIS correction.…”
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26466
Bulk Nanobubbles Fabricated by Repeated Compression of Microbubbles
Published 2019“…The results show that NBs with a mean diameter of 240 ± 9 nm and a polydispersity index of 0.25 were successfully prepared. …”
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26467
Inhibitory effect of TF3 on Hla production by <i>Staphylococcus aureus</i> USA300.
Published 2023“…(B) Densitometry of western blot bands. (C) Dose-dependent decrease in <i>hla</i> and <i>agr</i>A genes expression by <i>S</i>. …”
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26468
Temporal and Spatial Profiling of Root Growth Revealed Novel Response of Maize Roots under Various Nitrogen Supplies in the Field
Published 2012“…Early N excess, deficiency, or delayed N topdressing reduced plant N content, resulting in a significant decrease in dry matter accumulation and grain yield. …”
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26469
Comparison between empirical data and simulation results of FSIR and SIR models.
Published 2015“…The degree distribution is chosen at <i>P</i>(<i>k</i>) ∼ <i>k</i><sup>−2.5</sup>, <i>k</i><sub><i>min</i></sub> = 20 and ⟨<i>k</i>⟩ ≈ 50. …”
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26470
Mutational scanning of autologous virus.
Published 2023“…The top panel shows fold increase/decrease while the bottom shows IC<sub>50</sub> (μg/ml). …”
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26471
Effect of replacing beef fat with safflower oil on physicochemical, nutritional and oxidative stability characteristics of wieners
Published 2021“…Incorporation of SO increased CIE L* and b* values, whereas it caused a decrease in CIE a* values of wieners (P < 0.05). …”
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26472
Label-free real-time multi-parametric monitoring enables high content analysis.
Published 2013“…The effect on the APD was determined for one hour after doxorubicin application and revealed a concentration dependent response with an EC<sub>50</sub> value of 17 µM (n = 3 hCMC), (B) The impedance analysis revealed a concentration- and time-dependent decrease where IC<sub>50</sub> values could be determined for each time point (n = 5 hCMC). …”
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26473
CPEB3-KO mice with normal mechanical sensation were more sensitive to noxious heat than WT littermate mice.
Published 2016“…For each paw, a von Frey fiber was applied 5 times at 5-s intervals. …”
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26474
Silibinin and SIL inhibit HCVpp-mediated fusion.
Published 2013“…After a 2 min-equilibration, lipid mixing was initiated by decreasing the pH to 5.0 with diluted HCl, and R<sub>18</sub> dequenching was recorded. …”
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26475
Pirt contributes to histaminergic itch.
Published 2013“…<p>(<b>A</b>) The time course shows scratching bouts, presented as mean ± SEM, in response to histamine injection (10 µmol) over a 30 min period divided into 5 min intervals. …”
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26476
Kinases are recruited to the signaling complex by alternative N-t localization domains.
Published 2014“…In most cases, mutations that disrupt specific recruitment interactions decrease pathway activation between 40%–50%. MUT Ste20[N]-Ste50[C] might still localize to the signaling complex, as Ste50's RA domain binds Cdc42 independently of Ste20's PBD domain <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002012#pbio.1002012-Truckses1" target="_blank">[53]</a>. …”
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26477
Efficacy of Low-Dose Naltrexone in Treating Patients with Fibromyalgia: systematic Review and Meta-Analysis
Published 2025“…This systematic review and meta-analysis aimed to evaluate the efficacy of LDN for fibromyalgia. We systematically searched electronic databases and gray literature from inception to May 2024. …”
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26478
Comprehensive Experimental and Theoretical Study of the CO + NO Reaction Catalyzed by Au/Ni Nanoparticles
Published 2019“…However, in situ extended X-ray absorption fine structure spectroscopy showed a good correlation between Au–Ni coordination number (highest for Ni<sub>50</sub>Au<sub>50</sub>) and catalytic activity. …”
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26479
Map of thermal risk variation, based on the response of lizards to dehydration for <i>Loxopholis percarinatum</i> across the amazon basin.
Published 2023“…D represents thermal risk after a 50% decrease in rainfall, E shows risk after a decrease of 20% in tree cover, and F shows the risk for lizards with VTmax = 28.8°C, The median VTmax for <i>L</i>. …”
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26480
Time to virus extinction.
Published 2024“…The smoothing term for the simulation with inhibitory virophages was significant to the level of p < 10<sup>−5</sup>. The normalised root mean squared error (RMSE) is 14.6% and the deviance explained is 69.3%. …”