Repetitive stress induces a reduction in sound-evoked activity that develops as the stressor becomes chronic. by Ghattas Bisharat (20706928)

“…Comparison of tone-evoked activity after a day and 5 days of stress to baseline. On the initial day of stress, there was no significant reduction in activity, but as the stressor became chronic, the reduction increased (mean ± SE, 1-way ANOVA, condition S1 F = 1.9, <i>p</i> = 0.16, S5 F = 27.5, <i>p</i> = 1.7 × 10⁻⁰⁷, nested ANOVA (mouse nested within session) condition S1 F = 2.8, <i>p</i> = 0.09, S5 F = 32.7, <i>p</i> = 1.3 × 10⁻⁰⁸). …”

Manual RT-PCR measurements of 3 selected miRNAs agree very well with measurements performed by TLDA assay. by Neil R. Smalheiser (179141)

“…<p>The control and schizophrenia samples of Experiment 1 were measured using individual TaqMan primer sets for miR-17, miR-145-5p and miR-219-2-3p. Note that lower Ct values indicate higher abundance on a log2 scale (i.e., a decrease of 0.5 Ct represents a 41% increase in abundance or 1.41-fold difference across groups). …”

Cell cycle distribution of primary human B cells infected with miRNA-mutant or prototype 2089 EBVs. by Eri Seto (243456)

“…<p>Primary B cells (4.5×10⁵ per ml) were infected with an MOI of 0.05 of each virus stock as indicated or left uninfected. …”

EEG and PSD Measures in Sleep-Deprived Monkeys by Linda J Porrino (380497)

“…Reduction of sleep deprivation features of PSD in same animals following administration of CX717 (0.8 mg/kg) is indicated at right by a decrease in PSD delta band (0.5–5 Hz, dotted line) and reduction in power of peaks (asterisks) in the beta band (18–25 Hz). …”

Early isolates of HIV-1 from the blood are deficient in binding and/or fusion with CD4 from some primate species. by Cody J. Warren (563898)

“…Data associated with this figure can be found in the supplemental data file (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000304#pbio.3000304.s009" target="_blank">S5 Data</a>). CCR5, C-C motif chemokine receptor 5.…”

Diet regulates the metabolic state and functioning of the heart during acute infection. by Fnu Nagajyothi (37087)

“…<p>(<b>a</b>) mPET analysis demonstrated a significant increase in the mean value of the myocardial standard uptake value for the glucose analogue, ¹⁸F-FDG in the infected RD fed mice compared to HFD infected mice at d30pi (n = 5). …”

DataSheet_1_Clinical manifestations and associated factors in acquired hypoaldosteronism in endocrinological practice.docx by Jorge Gabriel Ruiz-Sánchez (9704612)

“…</p>Results<p>Patients had a median age of 77 [65 – 84], 55.4% were male. 94.6% cases showed hyperkalemia, 54.5% HH, and 60.3% MA. The mean serum K+ of all cases was 5.4 ± 0.5 mmol/L, Na+: 132.1 ± 6.3 mmol/L, HCO3: 22.6 ± 3.3 mmol/L. …”

Treatment satisfaction with injectable disease-modifying therapies in patients with relapsing-remitting multiple sclerosis (the STICK study) by Oscar Fernández (166747)

“…</p><p>Results</p><p>The study included 445 patients (mean±SD age, 41±10.2 years; two-thirds women). The percentages treated with each DMT were Avonex 28.5%, Rebif 44 μg 24.5%, Copaxone 22.5%, Betaferon 13.0%, Rebif22 μg 8.3% and Extavia 3.1%. …”

Properties of axonal GABA_A receptors. by Yang Xia (104600)

“…B, Left, an example trace showing an increase in outward holding current after bath application of 5 µM muscimol (V_hold = 10 mV) and the blockade of this increase by 100 µM PTX. …”

Safety and Efficacy of Sustained Automated Insulin Delivery Compared to Sensor and Pump Therapy in Adults with Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlle... by Eric Renard (6509036)

“…RESULTS Compared to S&P, AID resulted in significant: (i) reduction of TBR by -3.7% (95%CI -4.8, -2.6), p<0.001; (ii) increase of TIR by +8.6% (95%CI +5.2, +12.1), p<0.001, and (iii) decrease of TAR by -5.3% (95%CI -87.7, -1.8), p=0.004. …”

The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis by Jamialahmadi, Tannaz

“…Comprehensive Meta-Analysis V3 software was used to perform the meta-analysis. …”
Get full text
Get full text

Entrainment of network oscillations to weak electric field stimulation and effects on homeostatic synaptic downscaling. by Davide Reato (281995)

“…Note the rectification of the effect of fields on firing rate, which now only increases for inward stimulation but does not decrease for outward currents. <b>A.3</b>: Entrainment of the network with 0.31 V/m monophasic ON/OFF stimulation for purely cathodal (blue) or purely anodal (red) field. …”

Prostate cancer diagnosis, staging, and treatment in Sweden during the first phase of the COVID-19 pandemic by Giuseppe Fallara (9921948)

Stable global DNA methylation and hydroxymethylation and HMG-CoA reductase DNA hypermethylation in diet-induced NAFLD. by Tommy Pacana (790420)

“…Data are represented as mean ± SEM. Legend: B-cell lymphoma 2 (Bcl-2); DNA methyltransferase 1 and 3a (Dnmt 1 and Dnmt3a); fatty acid synthase (Fasn); 5-hydroxymethyl-2’-deoxycytidine (5hmdC); 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase, Hmgcr); nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (Nfkb1).…”

Quantifying the Human Cost of Global Warming (Data and Scripts) by Timothy M. Lenton (9965891)

“…Reducing global warming from 2.7 to 1.5 °C results in a ~5-fold decrease in the population exposed to unprecedented heat (MAT ≥29 °C). …”

Steady-state fluorescence studies provide additional support to the A region Model 3. by Sylvain Maenner (255271)

“…Cy3- and Cy5-labeled oligonucleotides were purchased from Eurogentec. …”

Exogenously administrated IL-33 in mice promoted type 2 immunity. by Zhonghan Yang (394041)

“…C, IL-33 injection induced increase in the permeability of intestinal mucosa (decrease in transepithelial electrical resistance, TEER) (n = 5 per group, **p<0.01 vs BSA-treated, <i>t</i> test). …”

<i>HNF1A</i> is necessary for reprogramming and sufficient in combination with two interchangeable transcription factors. by Kamen P. Simeonov (588591)

“…Data points shown are meanSD. Stars indicate p-val 0.001. (K) 5TF sample lacking <i>HNF1A</i> clusters with vehicle control separately from 6TF and other 5TF samples and away from hepatocytes based on 33 hepatic genes, supporting the absolute necessity of <i>HNF1A</i>.…”

Inhibition of FMDV in cell-based assays. by Ryan C. Durk (358547)

“…Error bars represent standard error of the mean for two experiments. At these inhibitor concentrations no decrease in cell viability was observed.…”

Supplemental Figure 2: Activation of the AHR with a mixture of agonists' results in further increase in SCC2 cell migration. from Role for the Aryl Hydrocarbon Receptor and Diverse... by Elizabeth A. Stanford (15077572)

“…Data from 3 experiments were normalized to results obtained with naïve cells and presented as mean percent exposed area + standard error. Asterisks indicate a significant decrease in exposed area, *p<0.05.…”