Early loss of SHH signaling in the tongue impinges upon growth and morphogenesis but is conducive to taste bud differentiation. by Maha El Shahawy (557888)

“…(<b>A</b>,<b>B</b>) Anti-Sonic hedgehog-stained (SHH; dark purple) sections of E15.5 control (A) and mutant (B) tongues showing focal epithelial hyperplasia (arrow in B) and severely decreased SHH immunostaining in the mutant. …”

UCH-L5 regulates inflammasome activity in chicken macrophages. by Evangel Kummari (719636)

“…</b> UCH-L5 was overexpressed in HD11 macrophages (UCH-L5) and empty vector was used as a control (ctrl). 24-hours past overexpression, the cells were subjected to <i>Salmonella</i> infection at MOI of 50:1 for 18-hours (inf) or left uninfected. …”

Cytokine production in GI and OI infected mice. by Juliana Barreto-de-Albuquerque (757911)

“…The results are expressed as the mean values (±SEM) for each group/day post-infection. n: IFN-γ, uninfected (0) = 12; 3 dpi GI = 11, OI = 5; 9 dpi GI = 8, OI = 5; 12 dpi GI = 9, OI = 4; 17 dpi GI = 4, OI = 6. …”

PI3Ks regulate plaque morphology and early protein production. by Shannon McNulty (248670)

“…<p><b>A.</b> PI3K inhibitors reduce plaque size in BSC40 cells. …”

Y-27632 mediated signal transduction during differentiation. by Roman J. Krawetz (309735)

“…<p>Total mRNA collected from all groups was converted to cDNA and probed to assay levels of β-catenin (A). β-catenin levels increased under all differentiation induction conditions, however, levels decreased significantly when Y-27632 was added during mesodermal and ectodermal differentiation. …”

Effect of aspirin on endometrial histomorphometry in PCOS rats during the window of implantation. by Ying Zhang (40767)

“…(HE staining, scare bar = 50μm). <b>(a)</b> Control group, the endometrial stroma is loose, with synchronous development of glands and stroma, abundant glands, and a rich vascular supply; <b>(b)</b> Model group, endometrial glandular hypoplasia is observed, characterized by small glandular lumina and a reduced number of glands, along with a decrease in vascularity; <b>(c)</b> Aspirin group, endometrial development shows improvement, manifested by larger glandular lumina, loose stroma, and an increased number of glands and vessels within the stroma. …”

Increased TCR avidity of memory CD4+ T cells in HIV controllers. by Benoît Vingert (252525)

“…<p>(A) The TCR avidity of Gag293-specific CD4+ T cells was determined by MHC class II tetramer staining in the presence of decreasing tetramer concentrations. …”

Sensitivity to starvation increases after knockdown of sNPF and DTK in neurosecretory cells. by Lily Kahsai (233920)

“…<b>C</b> Kurs 6-driven knockdown of DTK produces strongly diminished survival at starvation (about 12 h decrease at 50% survival) (P<0.001, Log-rank test; for each genotype n = 224–229).…”

Box plots showing the distribution of cell sizes and phase durations under the assumption of CDKA/B:CYCB over-expression (OE), wild-type expression (WT), and under-expression (UE). by Daniel Williamson (2869301)

“…<p>Wild-type had default parameter values, over-expression a 50% increase in CDKA/B:CYCB synthesis rate and under-expression a 20% decrease. …”

Box plots showing the distribution of cell sizes and phase durations under the assumption of CDKA:CYCD over-expression (OE), wild-type expression (WT), and under-expression (UE). by Daniel Williamson (2869301)

“…<p>Wild-type had default parameter values, over-expression a 50% increase in CDKA:CYCD synthesis rate and under-expression a 20% decrease. …”

Reduced Lateral Mobility of Lipids and Proteins in Crowded Membranes by Joseph E. Goose (401716)

“…The increase in protein concentration also resulted in a decrease in the anomalous diffusion exponent α of the lipid. …”

Efficient inhibition of EGFP expression by zebrafish mir-30e precursor <i>in vivo</i>. by Mei Dong (157261)

“…The capped EGFP sensor mRNAs were co-injected with either miR-30e or miR-155 precursor mRNAs into one-cell stage embryos (B, bottom). (C) A dramatic decrease of EGFP fluorescence in 24 hpf embryos co-injected with EGFP-2×PT^mir30e sensor (10 pg) and miR-30e precursor (50 pg). …”

Image_4_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Image_5_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Image_3_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Image_1_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Data_Sheet_1_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.docx by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Image_2_Telomere Length but Not Mitochondrial DNA Copy Number Is Altered in Both Young and Old COPD.TIFF by Sandra Casas-Recasens (6187661)

“…The short telomeres were found both in the young and old patients with severe COPD (FEV₁ <50% ref.). In addition, we found that TL and mtDNA-CN were significantly correlated, but their relationship was positive in younger while negative in the older patients with COPD, suggesting a mitochondrial dysfunction. …”

Flexible, Suturable, and Leak-free Scaffolds for Vascular Tissue Engineering Using Melt Spinning by Julia Fernández-Pérez (16649098)

“…The scaffolds with a higher angle between fibers showed increased expression of vSMC markers alpha smooth muscle actin, calponin, and smooth muscle protein 22-alpha, whereas a decrease in collagen 1 expression was observed, indicating a positive contractile phenotype. …”

Flexible, Suturable, and Leak-free Scaffolds for Vascular Tissue Engineering Using Melt Spinning by Julia Fernández-Pérez (16649098)

“…The scaffolds with a higher angle between fibers showed increased expression of vSMC markers alpha smooth muscle actin, calponin, and smooth muscle protein 22-alpha, whereas a decrease in collagen 1 expression was observed, indicating a positive contractile phenotype. …”