A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia by Nagore I. Marín-Ramos (1600555)

“…In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. …”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia by Nagore I. Marín-Ramos (1600555)

“…In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. …”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia by Nagore I. Marín-Ramos (1600555)

“…In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. …”

Trypacidin, a Spore-Borne Toxin from <em>Aspergillus fumigatus</em>, Is Cytotoxic to Lung Cells by Thierry Gauthier (185229)

“…Trypacidin was the most toxic, decreasing cell viability and triggering cell lysis, both effects occurring at an IC₅₀ close to 7 µM. …”

Raw data. by Changzhi Liu (518454)

“…This study aimed to explore the association between RC levels and the risk of vertebral fractures in a longitudinal cohort.</p><p>Methods</p><p>A total of 1995 participants aged 50 years or older who underwent chest computed tomography (CT) scans for lung cancer screening between July 2016 and December 2019 were included in this study. …”

Model of PdcB and PdcC phase variation in the context of c-di-GMP signaling in <i>C</i>. <i>difficile</i>. by Leila M. Reyes Ruiz (6690206)

Baseline characteristics of the subjects. by Changzhi Liu (518454)

“…This study aimed to explore the association between RC levels and the risk of vertebral fractures in a longitudinal cohort.</p><p>Methods</p><p>A total of 1995 participants aged 50 years or older who underwent chest computed tomography (CT) scans for lung cancer screening between July 2016 and December 2019 were included in this study. …”

Knockdown of nr2f1a causes defects in zebrafish vascular development. by Bao-Jueng Wu (621818)

“…At the same stage ISVs are stalled at mid-somite in nr2f1a^e2i2 morphants (<b>D, F</b>). (<b>I</b>) Quantification of percentage of completed ISV shows a ∼50% increase compared to <i>nr2f1a</i> morphants (n = 26 in wt and n = 34 in nr2f1aMO) at 30 hpf. …”

Parity and Pancreatic Cancer Risk: A Dose-Response Meta-Analysis of Epidemiologic Studies by Hong-Bo Guan (464993)

“…</p><p>Conclusion</p><p>In summary, these findings suggest that higher parity is associated with a decreased risk of PC. Future large consortia or pooled studies are warranted to fully adjust for potential confounders to confirm this association.…”

The effects of stepwise changes in stimulus intensity on spike timing. by Alejo Rodríguez-Cattáneo (19713314)

Dengue and malaria spatio-temporal patterns in Loreto. by Gabriel Carrasco-Escobar (794055)

The <i>pdcB</i> switch contains an invertible promoter. by Leila M. Reyes Ruiz (6690206)

S2 Data - by Tamara Mogilevski (14239682)

“…</p><p>Methods</p><p>In a single-blinded, cross-over, randomised study, healthy volunteers received on separate days corticotropin-releasing hormone (CRH, 100 μg) or normal saline (as placebo) intravenously in random order, then a HFHC meal. …”

Study protocol. by Tamara Mogilevski (14239682)

“…</p><p>Methods</p><p>In a single-blinded, cross-over, randomised study, healthy volunteers received on separate days corticotropin-releasing hormone (CRH, 100 μg) or normal saline (as placebo) intravenously in random order, then a HFHC meal. …”

S1 Data - by Tamara Mogilevski (14239682)

“…</p><p>Methods</p><p>In a single-blinded, cross-over, randomised study, healthy volunteers received on separate days corticotropin-releasing hormone (CRH, 100 μg) or normal saline (as placebo) intravenously in random order, then a HFHC meal. …”

Comparison of various inducer treatments on physiological and biochemical parameters in plants under drought conditions, relative to both drought-stressed and well-watered control... by Shelina Akter Sheuli (22446598)

Comparison of various inducer treatments on physiological and biochemical parameters in plants under normal conditions, relative to well-watered control plants. by Shelina Akter Sheuli (22446598)

Antioxidant Carbocysteine Treatment in Obstructive Sleep Apnea Syndrome: A Randomized Clinical Trial by Kang Wu (160544)

“…The CPAP group also showed a decreased oxygen desaturation index and a significant increase in the mean oxygen saturation after treatment, but these increases were not observed in the carbocysteine group. …”

Image_2_A comparison of rat models that best mimic immune-driven preeclampsia in humans.jpeg by Fahmida Jahan (17057388)

“…Of the three rodent models tested, we found that Poly I:C and LPS decreased both fetal weight and survival; and correlated with a reduction in region specific placenta growth. …”

Image_1_A comparison of rat models that best mimic immune-driven preeclampsia in humans.jpeg by Fahmida Jahan (17057388)

“…Of the three rodent models tested, we found that Poly I:C and LPS decreased both fetal weight and survival; and correlated with a reduction in region specific placenta growth. …”