The Effect of Intravenous Immunoglobulin Combined with Corticosteroid on the Progression of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Meta-Analysis by Liang-ping Ye (3370709)

“…<div><p>Background</p><p>Intravenous immunoglobulin (IVIG) treatment is commonly used to treat Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) with controversial therapeutic effect.</p><p>Methods</p><p>We conducted a comprehensive meta-analysis through combining the published eligible studies to evaluate the effectiveness of IVIG on SJS and TEN treatment.…”

Purified recombinant WT-C100Flag dimer and trimer showed reduced Aβ production. by Joo In Jung (650746)

“…Aβ38, Aβ40 and Aβ42 levels decreased in dimer compared to monomer, and the Aβ levels for trimer were under detection limits. …”

Accessibility of HSV DNA during infection as determined by ATAC-seq. by Joseph M. Cabral (10719500)

“…Data are reported as the average of 2 independent experiments, except for the 4hpi data in (A) in which 4 replicates were included, ± standard error of the mean; p < 0.05 (*). (C) ATAC- seq reads that align to the HSV genome in samples from proteinase K treated HSV (KOS) genomes, Control cells and ATRX-KO cells infected with 7134 at MOI 5 and harvested at 4 and 8 hpi. …”

<i>Hbp1</i> expression in <i>Rb</i>^<i>+/+</i> and <i>Rb</i>^<i>-/-</i> mutant XY gonads. by Cassy M. Spiller (3687520)

“…When gene expression was normalized to germ cell marker <i>Mvh</i>, both <i>Fl-Hbp1</i> <b>(D)</b> and <i>ΔHbp1</i> <b>(E)</b> gene expression was significantly decreased in 16.5 dpc <i>Rb</i>^<i>-/-</i> cultured XY gonads. …”

Demonstration of a Direct Interaction between β₂-Adrenergic Receptor and Insulin Receptor by BRET and Bioinformatics by Maja Mandić (662591)

“…In heterologous competition assays, a transient increase in the BRET² signal with a subsequent hyperbolical decrease was observed, suggesting higher-order heteromer formation. …”

Phenoxodiol protects against Cisplatin induced neurite toxicity in a PC-12 cell model-2 by Reuben Klein (78663)

“…</p><p></p>XD for 24 hrs then fixed and immunostained for the neuronal marker βIII-tubulin. A) Control cultures showed a large percentage of cells with long neurites, which were also present in B) 100 nM PXD and C) 1 μM PXD. …”

NOS inhibition with LNNA enhances tone in response to intramural pressure changes but not in the presence of a constant pressure. by Katrin Reimann (290872)

“…Note that the vascular diameter at 60 cmH₂O decreased in vessel segments that were exposed to pressure variations but not in vessel segments that were exposed to a constant pressure and that the diameter in Ca²⁺ free solution was similar in both groups. …”

Far-UV CD spectra of pEAβ(3–40) and Aβ(1–40). by Christina Dammers (803567)

“…(a) CD spectra of 25 μM pEAβ(3–40) in 25%, 23%, 22%, 21% and 20% TFE showed a shift from α-helical structure towards β-sheets with decreasing TFE concentrations. …”

Image_4_Efficacy of topical and systemic treatments for atopic dermatitis on pruritus: A systematic literature review and meta-analysis.tif by Youna Rodriguez-Le Roy (14292449)

“…In the meta-analysis without TCS, the overall decrease was 3.07/10, 95% IC [2.58–3.56]. The molecules with the highest efficacy on pruritus were upadacitinib 30 mg (mean: 4.90) and nemolizumab (mean: 4.81).…”

Image_2_Efficacy of topical and systemic treatments for atopic dermatitis on pruritus: A systematic literature review and meta-analysis.tif by Youna Rodriguez-Le Roy (14292449)

“…In the meta-analysis without TCS, the overall decrease was 3.07/10, 95% IC [2.58–3.56]. The molecules with the highest efficacy on pruritus were upadacitinib 30 mg (mean: 4.90) and nemolizumab (mean: 4.81).…”

Image_1_Efficacy of topical and systemic treatments for atopic dermatitis on pruritus: A systematic literature review and meta-analysis.tif by Youna Rodriguez-Le Roy (14292449)

“…In the meta-analysis without TCS, the overall decrease was 3.07/10, 95% IC [2.58–3.56]. The molecules with the highest efficacy on pruritus were upadacitinib 30 mg (mean: 4.90) and nemolizumab (mean: 4.81).…”

Image_3_Efficacy of topical and systemic treatments for atopic dermatitis on pruritus: A systematic literature review and meta-analysis.tif by Youna Rodriguez-Le Roy (14292449)

“…In the meta-analysis without TCS, the overall decrease was 3.07/10, 95% IC [2.58–3.56]. The molecules with the highest efficacy on pruritus were upadacitinib 30 mg (mean: 4.90) and nemolizumab (mean: 4.81).…”

Structural and Functional Effect of an Oscillating Electric Field on the Dopamine-D3 Receptor: A Molecular Dynamics Simulation Study by Zohreh Fallah (3342287)

“…Computing the correlation coefficient parameter showed that increasing the field frequency can weaken the interaction between dopamine and D3R and may decrease the Arg128{3.50}-Glu324{6.30} distance. Because of high stability of α helices along the z-direction, applying an oscillating electric field in this direction with an amplitude 10-time higher did not have a considerable effect. …”

Image_1_Molecular mechanisms regulating natural menopause in the female ovary: a study based on transcriptomic data.jpeg by Quan Liu (486219)

“…Increased contents of terminally differentiated HMGB1+ Granulosa and GSTA1+ Granulosa were observed in the ovaries of individuals aged 50-69. Signaling pathway activity analysis indicated a gradual decrease in TGFb and MAPK pathway activity with menopause progression, while p53 pathway activity increased. …”

Post-Exercise Hypotension and Its Mechanisms Differ after Morning and Evening Exercise: A Randomized Crossover Study by Leandro C. de Brito (771988)

“…Sixteen pre-hypertensive men underwent four sessions (random order): two conducted in the morning (7:30am) and two in the evening (5pm). At each time of day, subjects underwent an exercise (cycling, 45 min, 50%VO₂peak) and a control (sitting rest) session. …”

Fig 4 - by Sunggyun Park (11978733)

Effects of supplemental light on tomato rapid chlorophyll fluorescence induction kinetic curves. by Xiaoling Yang (27940)

Western blot analyses of pull-down assays for the whole Rac protein and a Rac effector domain. by Yudai Matsuoka (9986881)

“…<p>The extent of decreased Rac activity in OSC-19 and HOC313 cells was more significant than that in OSC-20 cells and fibroblasts. …”

NeoA inhibits cellular adhesion and causes the disassembly of focal adhesions in MDA-MB-231 cells. by Pamela Austin (248283)

“…(C) Cells pre-attached on fibronectin begin to lose adherence between 10 to 25 min after the start of treatment with 6.5 µM NeoA. Scale bar, 50 µm.</p>…”

Datasheet1_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.pdf by Elena Chiappini (304802)