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19501
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19502
GWAS analysis identifies several single nucleotide polymorphisms (SNPs) that are associated with the changes in viral copies.
Published 2024“…(C) The corresponding synonymous (triangles) and non-synonymous (circles) amino acid changes that associate with increased or decreased viral copies. Data is shown as means with 95% confidence intervals. …”
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19503
Inhibition of Enterovirus 71 (EV-71) Infections by a Novel Antiviral Peptide Derived from EV-71 Capsid Protein VP1
Published 2012“…The <em>in vitro</em> inhibitory effect of SP40 exhibited a dose dependent concentration corresponding to a decrease in infectious viral particles, total viral RNA and the levels of VP1 protein. …”
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19504
Table_1_The Groove Enhancement Machine (GEM): A Multi-Person Adaptive Metronome to Manipulate Sensorimotor Synchronization and Subjective Enjoyment.DOCX
Published 2022“…In predicting enjoyment, we found an interaction between auditory feedback and metronome adaptivity, with increased enjoyment at optimal levels of adaptivity only with auditory feedback and a severe decrease in enjoyment at higher levels of adaptivity, especially without feedback. …”
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19505
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19506
A role for <i>bmm</i> function in the somatic cells of the gonad in the regulation of whole-body triglyceride storage and breakdown in males.
Published 2020“…(I–K) Using an LD-GFP, we found that a subset of the LipidTOX-positive lipid droplets in the testis (arrowheads) represent droplets in the somatic cells of the gonad. …”
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19507
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19508
Table_1_The responses of soil microbial characteristics to nitrogen addition and biochar amendment in a Larix kaempferi plantation.docx
Published 2023“…However, the impacts of biochar on the microbial characteristics of soil after short-term N deposition in subtropical plantations remain poorly understood. Here, we investigated the effects of biochar application (0, 5, 10 t ha<sup>−1</sup>) on soil chemical traits and microbial characteristics (extracellular enzyme activities, microbial community and microbial biomass) in a Larix kaempferi plantation in Shennongjia, China, under N addition (0, 50, 100 kg N ha<sup>−1</sup> yr<sup>−1</sup>) during two growing seasons. …”
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19509
Identification of Chalcones as <i>Fasciola hepatica</i> Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach
Published 2016“…One of the compounds, <b>C34</b>, tightly bounds to juvenile specific <i>Fh</i>CL3 with an IC<sub>50</sub> of 5.6 μM. We demonstrated that <b>C34</b> is a slow-reversible inhibitor that interacts with the Cys-His catalytic dyad and key S<sub>2</sub> and S<sub>3</sub> pocket residues, determinants of the substrate specificity of this family of cysteine proteases. …”
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19510
Interventions to improve antiretroviral therapy adherence among adolescents in low- and middle-income countries: A systematic review of the literature
Published 2018“…Moreover, HIV-related mortality increased by 50% between 2005 and 2012 for adolescents 10–19 years while it decreased by 30% for all other age groups. …”
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19511
Motivation to participate in high-intensity functional exercise compared with a social activity in older people with dementia in nursing homes
Published 2018“…</p><p>Methods</p><p>The Umeå Dementia and Exercise Study (UMDEX) was a cluster-randomized controlled intervention trial including 186 people (mean age; 85, 75% female) with dementia in nursing homes. …”
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19512
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19513
The effectiveness of an on-line training program for improving knowledge of fire prevention and evacuation of healthcare workers: A randomized controlled trial
Published 2018“…However, face-to-face fire prevention and evacuation training may take healthcare workers’ time away from patient care; therefore, effective on-line training may be warranted. We carried out and examined the effectiveness of an on-line education and training of fire prevention and evacuation training for healthcare workers in China by a randomized controlled trial using convenience sampling from five public hospitals in China.…”
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19514
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19515
Data Sheet 2_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx
Published 2024“…</p>Result<p>MR analysis indicated that glucosamine was associated with increased cognitive performance (p = 8.46E-04), FIS (p = 7.50E-04), ALM (p = 6.45E-08), WBFM (p = 1.97E-03), usual walking pace (p = 2.55E-07), and moderate to vigorous physical activity levels (p = 3.29E-03), but associated with decreased FA risk (p = 3.77E-05) and DNA methylation GrimAge acceleration (p = 0.001). …”
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19516
DataSheet_1_Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis.docx
Published 2024“…Reverse MR analysis was used to detect reverse causal relationships.</p>Results<p>We identified 23 causal links between specific gut microbiota taxa and SpA levels. …”
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19517
Table_1_Gut microbiota and type 1 diabetes: a two-sample bidirectional Mendelian randomization study.xlsx
Published 2023“…Objective<p>The real causal relationship between human gut microbiota and T1D remains unclear and difficult to establish. Herein, we adopted a two-sample bidirectional mendelian randomization (MR) study to evaluate the causality between gut microbiota and T1D.…”
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19518
Interplay between fungicides and parasites: Tebuconazole, but not copper, suppresses infection in a <i>Daphnia-Metschnikowia</i> experimental model
Published 2017“…Most importantly, while copper and parasite effects were mostly independent, tebuconazole suppressed infection. In a follow-up experiment, we tested the effect of a lower range of tebuconazole concentrations (0.00, 6.25, 12.5, 25.0, 50.0 and 100 μg L<sup>-1</sup>) crossed with increasing parasite challenge (2 <i>Daphnia</i> clones × 6 contaminant concentrations × 2 parasite levels × 20 replicates = 480 experimental units). …”
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19519
Data Sheet 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx
Published 2024“…</p>Result<p>MR analysis indicated that glucosamine was associated with increased cognitive performance (p = 8.46E-04), FIS (p = 7.50E-04), ALM (p = 6.45E-08), WBFM (p = 1.97E-03), usual walking pace (p = 2.55E-07), and moderate to vigorous physical activity levels (p = 3.29E-03), but associated with decreased FA risk (p = 3.77E-05) and DNA methylation GrimAge acceleration (p = 0.001). …”
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19520
A Meta-Analysis of Anti-Vascular Endothelial Growth Factor Remedy for Macular Edema Secondary to Central Retinal Vein Occlusion
Published 2013“…</p><p>Methods</p><p>Data were collected and analyzed by Review Manager 5.2.1. We employed a random-effects model to eliminate between-study heterogeneity. …”