Image1_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.JPEG by Roberto Martin-Hernandez (3661549)

“…The discriminative power of the multi-omics signature and their regulators was delineated by training a random forest classifier using 55 samples, by employing a 10-fold cross validation with five iterations. …”

Mislocalized ADCY in rod outer segments induces photoreceptor cell death. by Takeshi Nakao (173997)

“…<p>(A) Expression analysis of adenylyl cyclases in wild-type retina by RT-PCR. …”

Electrical impedance cole parameters. by W. David Arnold (3373874)

Surface roughness and mechanical testing of sintered nylon and PCL. by Ian S. Kinstlinger (2164438)

“…<p>a) Surface roughness (R_a) of PCL decreases nearly 30-fold as a result of vapor-smoothing. …”

Med promotes bone regeneration at the drill hole site in Ovx osteopenic rats. by Manisha Dixit (777718)

“…^c<i>P</i>< 0.001 compjared with Sham + vehicle group; ^b<i>P</i>< 0.01compared with Sham + vehicle group; ^a<i>P</i>< 0.05compared with Sham + vehicle group; ^z<i>P</i>< 0.001 compared with Ovx + vehicle group; ^y<i>P</i>< 0.01 compared with Ovx + vehicle group; ^x<i>P</i>< 0.05 compared with Ovx + vehicle group; ^r<i>P</i>< 0.001 compared with Ovx + 0.5mg/kg med group; ^p<i>P</i>< 0.05 compared with Ovx + 0.5mg/kg med group; ^l<i>P</i>< 0.001 compared with Ovx + 1.0mg/kg med group; ^k<i>P</i>< 0.01 compared with Ovx + 1.0mg/kg med group; ^j<i>P</i>< 0.05 compared with Ovx + 1.0mg/kg med group; ^o<i>P</i>< 0.001 compared with Ovx + 5.0mg/kg med group; ^m<i>P</i>< 0.05 compared with Ovx + 5.0mg/kg med group.…”

JSI-124 inhibits cell viability and induces apoptosis in HUVECs. by Guang Yuan (706248)

“…(D) and (E) JSI-124 downregulated the level of p-STAT3, decreased the expression of Bcl-2 and Bcl-xL, and induced cleavage of caspase-3 and PARP in HUVECs in a dose-dependent manner by western blot analysis. …”

Inhibition of AKR1B1 substrate oxidation by β-glucogallin. by Muthenna Puppala (175119)

“…<p>A) Data were nonlinearly fit to the Michaelis-Menten model in the absence and presence of 0, 10, 20, and 40 µM β-glucogallin. …”

Neurotrophic factor gene profile of E14 spinal cord derived-progenitor cells during differentiation <i>in vitro.</i> by Masaya Nakamura (121832)

“…<p>After 2–4 passages, cells were seeded on the PEI-coated culture flasks at a density of 2×10⁵ cells/ml in the differentiation medium (no EGF/FGF2, 1% FBS). …”

miR-105 levels are reduced in prostate tumour cells compared to normal prostate epithelial cells. by D. Rice Honeywell (442714)

<i>rhlAB</i> promoter activity during different phases of growth in nutrient limitation batch culture. by Kerry E. Boyle (759216)

“…<p>GFP and promoter activity data are from the same growth curves shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004279#pcbi.1004279.g002" target="_blank">Fig 2</a>. …”

Data_Sheet_1_Microbial Degradation of Citric Acid in Low Level Radioactive Waste Disposal: Impact on Biomineralization Reactions.docx by Natalie Byrd (10715205)

“…Sulfate reduction only occurred in a single microcosm at pH 10. Here, citrate was fully removed from solution, alongside ingrowth of acetate and formate, likely fermentation products. …”

Data_Sheet_1_Insightful Backbone Modifications Preventing Proteolytic Degradation of Neurotensin Analogs Improve NTS1-Induced Protective Hypothermia.docx by Santo Previti (4350607)

“…Neurotensin (NT), which exerts its effects through activation of two G protein-coupled receptors, namely NTS1 and NTS2, induces a strong and long-lasting decrease in core body temperature after its central administration. …”

Data_Sheet_1_Assessing the in vivo ameliorative effects of Lactobacillus acidophilus KLDS1.0901 for induced non-alcoholic fatty liver disease treatment.docx by Yanbo Wang (618744)

“…A conspicuous decrease of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum was observed after L. acidophilus KLDS1.0901 administration. …”

SCI alters the mRNA expression of canonical Wnt signalling components. by Carmen María Fernández-Martos (5649061)

“…<p>Expression of the canonical co-receptor <i>LRP5/6</i>, the downstream intracellular inhibitory transducer <i>GSK3-ß</i> and the <i>ß-catenin</i> transcription factor were quantified by qRT-PCR as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027000#pone-0027000-g001" target="_blank">Figure1</a>. …”

Vsp1 associates with brain endothelium. by Gaurav Gandhi (239145)

“…Notice that Eu-LVsp1 associated with HBMEC in a time-dependent manner (panels A–C); also notice that the association of LVsp1 with HBMEC was saturable (panel A), did not occur with non-lipidated rVsp1 or albumin (panel B), and decreased by incubation at lower temperature (panel C).…”

Induction of experimental dry eye. by Susan R. Heimer (418710)

“…(A) EDE resulted in significant decreases in tear volume after 2 days. …”

There was no difference in AAR between the different groups by Matthias Götberg (43623)

“…(b) Infarct size (IS) measured by ex-vivo MRI as a percentage of area at risk (AAR) by SPECT in the two groups. …”

Sizes and lifetimes of clathrin-coated structures forming at the cell surfaces. by Saveez Saffarian (249084)

“…The data derive from time series (100-ms exposures) of at least 15-min duration recorded every 5 s (full circles) or 60-min duration recorded every 10 s (empty circles) using a spinning disk confocal fluorescence microscope. …”

CUSPER-based demonstration of detachment and re-attachment of bacterial cells at the agarose-water interface. by Annemieke van der Wal (195948)

Wnt signalling in normal breast cell lines (N), ER-ve (T−) and ER+ve (T+) breast cancer cell lines. by Rebecca Lamb (105412)