Showing 1,841 - 1,860 results of 226,433 for search '(( 5 ((step decrease) OR (nn decrease)) ) OR ( 10 ((teer decrease) OR (a decrease)) ))', query time: 1.43s Refine Results
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    CHIP Regulates AKT/FoxO/Bim Signaling in MCF7 and MCF10A Cells by Yanrong Lv (500561)

    Published 2013
    “…In the present study, we demonstrated that the abnormal overexpression of the C terminus of Hsc70-interacting protein (CHIP) induced apoptosis resistance by regulating the AKT/FoxO/Bim signaling pathway in the breast cancer cell MCF7 and the human non-tumorigenic cell MCF10A. We found that CHIP overexpression in MCF7 and MCF10A cells activated AKT and inhibited the Forkhead box O (FoxO) transcription factors FoxO1, FoxO3, and FoxO4, thereby inhibiting transcription of the target genes <i>bim</i> and <i>pten</i>. …”
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    Model. by Anne-Laure Pauleau (7430555)

    Published 2019
    “…This hypothesis is supported by our finding that the CENP-A loading factor CAL1 directly interact with the SAC component and RZZ subunit Zw10. …”
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