Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1 by Lisa M. Ryno (1323840)

Neurodegeneration and Motor Dysfunction in Mice Lacking Cytosolic and Mitochondrial Aldehyde Dehydrogenases: Implications for Parkinson's Disease by Margaret Chia-Ying Wey (181979)

Estimation of actomyosin active force maintained by tropomyosin and troponin complex under vertical forces in the <i>in vitro</i> motility assay system by Shuya Ishii (4840320)

Image_1_Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.tif by Cheng Feng (436816)

“…The proportion of macrophages in the keloid was significantly elevated compared to the surrounding normal tissue, while cDC2 cells significantly decreased. Hotspot and pseudotime trajectory analysis indicated two modules of macrophage cells (Module2: highly expresses RNASE1, C1QA, CD163, CD14, C1QC, FCGRT, MS4A7; Module10: highly expresses APOC1, CTSB, CTSL, TYROBP), which exhibited the characteristics of tumor-associated macrophages, were upregulated in more-advanced keloid cells. …”

Table_2_Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.xlsx by Cheng Feng (436816)

“…The proportion of macrophages in the keloid was significantly elevated compared to the surrounding normal tissue, while cDC2 cells significantly decreased. Hotspot and pseudotime trajectory analysis indicated two modules of macrophage cells (Module2: highly expresses RNASE1, C1QA, CD163, CD14, C1QC, FCGRT, MS4A7; Module10: highly expresses APOC1, CTSB, CTSL, TYROBP), which exhibited the characteristics of tumor-associated macrophages, were upregulated in more-advanced keloid cells. …”

Table_1_Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.docx by Cheng Feng (436816)

“…The proportion of macrophages in the keloid was significantly elevated compared to the surrounding normal tissue, while cDC2 cells significantly decreased. Hotspot and pseudotime trajectory analysis indicated two modules of macrophage cells (Module2: highly expresses RNASE1, C1QA, CD163, CD14, C1QC, FCGRT, MS4A7; Module10: highly expresses APOC1, CTSB, CTSL, TYROBP), which exhibited the characteristics of tumor-associated macrophages, were upregulated in more-advanced keloid cells. …”

Image_4_Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.tif by Cheng Feng (436816)

“…The proportion of macrophages in the keloid was significantly elevated compared to the surrounding normal tissue, while cDC2 cells significantly decreased. Hotspot and pseudotime trajectory analysis indicated two modules of macrophage cells (Module2: highly expresses RNASE1, C1QA, CD163, CD14, C1QC, FCGRT, MS4A7; Module10: highly expresses APOC1, CTSB, CTSL, TYROBP), which exhibited the characteristics of tumor-associated macrophages, were upregulated in more-advanced keloid cells. …”

Image_2_Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.tif by Cheng Feng (436816)

“…The proportion of macrophages in the keloid was significantly elevated compared to the surrounding normal tissue, while cDC2 cells significantly decreased. Hotspot and pseudotime trajectory analysis indicated two modules of macrophage cells (Module2: highly expresses RNASE1, C1QA, CD163, CD14, C1QC, FCGRT, MS4A7; Module10: highly expresses APOC1, CTSB, CTSL, TYROBP), which exhibited the characteristics of tumor-associated macrophages, were upregulated in more-advanced keloid cells. …”

Image_3_Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.jpeg by Cheng Feng (436816)

“…The proportion of macrophages in the keloid was significantly elevated compared to the surrounding normal tissue, while cDC2 cells significantly decreased. Hotspot and pseudotime trajectory analysis indicated two modules of macrophage cells (Module2: highly expresses RNASE1, C1QA, CD163, CD14, C1QC, FCGRT, MS4A7; Module10: highly expresses APOC1, CTSB, CTSL, TYROBP), which exhibited the characteristics of tumor-associated macrophages, were upregulated in more-advanced keloid cells. …”

Depletion of mDia2 in B16F1 Cells by siRNA by Changsong Yang (63501)

“…</p> <p>Scale bars indicate 10 μm in (A); 10 μm in (F); and 25 μm in (H).</p></div>…”

Comparison between PGK:Cre and Triple-Cre driven ablations. by Frédéric Causeret (223085)

“…At 4ss, <i>PGK:Cre;Dbx1^DTA</i> embryos show a strong decrease in the number of <i>sox10</i>⁺ premigratory CNCCs whereas <i>Triple-Cre;Dbx1^DTA</i> are less severely affected. …”

AR-mediated transcriptional regulation of apoptotic genes in HPr-1AR. by Congcong Chen (796149)

“…<p>(A) Cells were treated with 10 nM DHT or vehicle control for 24 hours. …”

PntP1 is maintained by Tll in type II NBs. by Rui Chen (95310)

“…White arrows point to type II NBs. Scale bars equal 10μm. (A-B’”) Wild type type II NB lineages have no Ase expression in the NBs and have higher expression levels of mCD8-GFP driven by <i>pntP1-GAL4</i> (A-A’”), whereas knockdown of Tll in type II NBs leads to ectopic Ase expression in type II NBs and a decrease in mCD8-GFP expression by 75% (B-B’”). mCD8-GFP intensity in the wild type type II NBs is normalized as 1 (A and A’”). …”

Chromatin conformation and bound CTCF sites at the mouse and chick <i>HoxD</i> locus. by Nayuta Yakushiji-Kaminatsui (6008795)

“…<p>(A) Hi-C heat map data adapted from [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000004#pbio.3000004.ref019" target="_blank">19</a>] at a 40-kb resolution. …”

Exploration of muscle loss and metabolic state during prolonged critical illness: Implications for intervention? by Liesl Wandrag (20467)

“…The data are consistent with a conclusion that a time based assumption of a tipping point does not exist.…”

Lig3-deficient mouse cells have fewer chromosomal translocations and reduced microhomology at junctions. by Deniz Simsek (218906)

“…Only junctions with simple deletions (i.e., without an insertion) are included. The probability that a junction will have <i>X</i> nucleotides of microhomology by chance assumes an unbiased base composition and is calculated as previously described <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002080#pgen.1002080-Simsek1" target="_blank">[9]</a>. …”

B*27:05-Y84C is more resistant to thermal denaturation and structurally more ordered in the peptide-receptive state. by Zeynep Hein (5586734)

“…Wild type B*27:05 shows a decrease in thermal stability in the absence of TAP2 (left) whereas B*27:05-Y84C is equally stable in STF1 and STF1-TAP2 cells. …”

Impact of ivermectin administered for scabies treatment on the prevalence of head lice in Atoifi, Solomon Islands by Suny Coscione (5786972)

“…Ivermectin is an effective treatment for both conditions, although the doses used vary. At a community level, mass drug administration (MDA) with ivermectin is an effective strategy to decrease prevalence of scabies. …”

Data_Sheet_1_Enhanced Store-Operated Ca2+ Signal of Small Intestinal Smooth Muscle Cells Accelerates Small Bowel Transit Speed in Type 1 Diabetic Mouse.PDF by Fang Dai (757649)

Drug-induced diabetes type 2: <i>In silico</i> study involving class B GPCRs by Dorota Latek (95762)