Pyrvinium inhibits Wnt signaling. by Sarika Saraswati (236578)

“…(<b>B</b>) Pyrvinium (100 nM) decreases transcript levels of endogenous Wnt target genes Myc, Dkk-1, and Axin2 as assessed by real-time PCR. …”

Kinetic characterizations of AChR blockade by PQ1–5. by Wan-Chen Lin (658261)

“…<p>(A) Single-channel currents of the AChR in the presence of 100 µM Ach ±5 µM <b>PQ5</b>. …”

Effect of TAK-242 on LPS-induced inhibition of myogenesis. by Yuko Ono (1443175)

“…(B) TAK-242 partially reversed the LPS-induced decrease in myogenic index. Cells were treated as described in (A). …”

Increased susceptibility to H₂O₂ production and cell death in TrxR2 deficient cells. by Pamela Lopert (114596)

“…At 100 µM, 300 µM and 1 mM PQ concentrations there was a significant increase in H₂O₂ released in the deficient cells compared to mock controls (n = 6) * = p<0.05 as determined 2-way ANOVA. …”

Effects of HFD on adipose macrophage infiltration, hypertrophy, and injury in NOX2-FL and mNOX2-KO mice. by Jennifer K. Pepping (4330654)

“…<b>(D)</b> Expression of GADD153/CHOP and GRP78 in tissue homogenates prepared from epididymal adipose depots. Data depict mean ± SEM expression in HFD mice presented as % values in CD mice (100% line on graph). *** indicates significant (p < 0.001) increases in expression in HFD-fed NOX2-FL mice compared to CD-fed NOX2-FL mice, while ### indicates significant (p < 0.001) decreases in expression in HFD-fed mNOX2-KO mice as compared to HFD-fed NOX2-FL mice.…”

Retinal structural changes well correlated with the ERG findings. by Victoria Peshti (3966533)

“…<p>(A) Representative retinal sections stained with hematoxylin and eosin demonstrate marked decrease of retinal thickness in KO eyes by the age of 6 months with further thinning by 10 months. …”

Antibacterial activity of rHPL. by Sim-Kun Ng (495657)

“…Control plate (0 µM) was defined as 100%-viable cells. Cell mortality was calculated as the decrease in the colony number compared with the control plate. …”

Pharmacological Wnt inhibition mimics β-catenin silencing in suppressing regenerative potential. by Chang Chen (30907)

“…<p><b>(A-D)</b> Wnt inhibitory factor-1 (WIF-1) treatment phenocopies β-catenin siRNA effects, including wound closure reduction (AB), invasion capacity decrease (CE), and proliferation decline <b>(D)</b>. …”

Flow cytometry analysis of apoptosis. by Igor Santos Fonte Bôa (838040)

“…<p>A) Dot plots showing the apoptosis ratios of kidney cells from Control (n = 4), CIN (n = 6), NAC (n = 6), V10 (n = 4), V100 (n = 4) and V300 (n = 4) groups subdivided into cortex (left panel) and medulla cells (right panel). …”

Random forest identifies metabolites that significantly distinguishes between WT and dKO group of mice. by Samit Ganguly (1792294)

“…RFA identified two groups (WT and KO) with 100% accuracy in both CSF (A) and plasma (B). Metabolites were plotted against their Mean Decrease in Accuracy, calculated by RFA. …”

<i>γ-Mtb</i>-mediated TF induction and TNF-α secretion is mostly independent of CD14. by Hema Kothari (306093)

“…Data is depicted as fold increase in TF activity over control (<b>B</b>) TNF-α levels as determined in ELISA. ns, not statistically significant; # indicates statistically significant decrease compared to LPS alone (<i>P</i><0.05). Data are mean ± SEM (n = 3–6).…”

Image_4_Ascorbic Acid-Induced Photosynthetic Adaptability of Processing Tomatoes to Salt Stress Probed by Fast OJIP Fluorescence Rise.TIF by Xianjun Chen (5711882)

“…Lower K- and L-bands and higher I-band were detected on the OJIP transient curves compared, respectively, with salt-stressed plants with and without LYC. AsA application also significantly increased the values of normalized total complementary area (S_m), relative variable fluorescence intensity at the I-step (V_I), absorbed light energy (ABS/CS_m), excitation energy (TR_o/CS_m), and reduction energy entering the electron transfer chain beyond Q_A (ET_o/CS_m) per reaction centre (RC) and electron transport flux per active RC (ET_o/RC), while decreasing some others like the approximated initial slope of the fluorescence transient (M_o), relative variable fluorescence intensity at the K-step (V_K), average absorption (ABS/RC), trapping (TR_o/RC), heat dissipation (DI_o/RC) per active RC, and heat dissipation per active RC (DI_o/CS_m) in the presence or absence of LYC. …”

Image_3_Ascorbic Acid-Induced Photosynthetic Adaptability of Processing Tomatoes to Salt Stress Probed by Fast OJIP Fluorescence Rise.TIF by Xianjun Chen (5711882)

“…Lower K- and L-bands and higher I-band were detected on the OJIP transient curves compared, respectively, with salt-stressed plants with and without LYC. AsA application also significantly increased the values of normalized total complementary area (S_m), relative variable fluorescence intensity at the I-step (V_I), absorbed light energy (ABS/CS_m), excitation energy (TR_o/CS_m), and reduction energy entering the electron transfer chain beyond Q_A (ET_o/CS_m) per reaction centre (RC) and electron transport flux per active RC (ET_o/RC), while decreasing some others like the approximated initial slope of the fluorescence transient (M_o), relative variable fluorescence intensity at the K-step (V_K), average absorption (ABS/RC), trapping (TR_o/RC), heat dissipation (DI_o/RC) per active RC, and heat dissipation per active RC (DI_o/CS_m) in the presence or absence of LYC. …”

Image_2_Ascorbic Acid-Induced Photosynthetic Adaptability of Processing Tomatoes to Salt Stress Probed by Fast OJIP Fluorescence Rise.TIF by Xianjun Chen (5711882)

“…Lower K- and L-bands and higher I-band were detected on the OJIP transient curves compared, respectively, with salt-stressed plants with and without LYC. AsA application also significantly increased the values of normalized total complementary area (S_m), relative variable fluorescence intensity at the I-step (V_I), absorbed light energy (ABS/CS_m), excitation energy (TR_o/CS_m), and reduction energy entering the electron transfer chain beyond Q_A (ET_o/CS_m) per reaction centre (RC) and electron transport flux per active RC (ET_o/RC), while decreasing some others like the approximated initial slope of the fluorescence transient (M_o), relative variable fluorescence intensity at the K-step (V_K), average absorption (ABS/RC), trapping (TR_o/RC), heat dissipation (DI_o/RC) per active RC, and heat dissipation per active RC (DI_o/CS_m) in the presence or absence of LYC. …”

Image_1_Ascorbic Acid-Induced Photosynthetic Adaptability of Processing Tomatoes to Salt Stress Probed by Fast OJIP Fluorescence Rise.TIF by Xianjun Chen (5711882)

“…Lower K- and L-bands and higher I-band were detected on the OJIP transient curves compared, respectively, with salt-stressed plants with and without LYC. AsA application also significantly increased the values of normalized total complementary area (S_m), relative variable fluorescence intensity at the I-step (V_I), absorbed light energy (ABS/CS_m), excitation energy (TR_o/CS_m), and reduction energy entering the electron transfer chain beyond Q_A (ET_o/CS_m) per reaction centre (RC) and electron transport flux per active RC (ET_o/RC), while decreasing some others like the approximated initial slope of the fluorescence transient (M_o), relative variable fluorescence intensity at the K-step (V_K), average absorption (ABS/RC), trapping (TR_o/RC), heat dissipation (DI_o/RC) per active RC, and heat dissipation per active RC (DI_o/CS_m) in the presence or absence of LYC. …”

Inhibition of KDM expression <i>in vivo</i>. by Hanitriniaina Rabeony (596171)

“…Skin sections were stained with Hematoxylin and immunodetection of cytokeratin 10, loricrin, filaggrin, involucrin and S100A7 was performed. Scale bar 100 µm. Results are from one experiment representative of three.…”

Specific induction of FABP4 in neovessels during OIR. by Magali Saint-Geniez (269693)

“…(C) Quantification of circulating FABP4 demonstrated a significant decrease of serum FABP4 levels in OIR P17 WT mice compared to control room air (RA). …”

Actin/calmodulin/tubulin, phosphatidylinositol (4,5)-bisphosphate, and ER-Golgi trafficking, are required for asymmetrical inheritance of protein aggregates. by Jia Song (495396)

“…Data are plotted as the mutants' deviation from the wild type in aggregate inheritance (open bars; 100% increase means a two-fold increase in the aggregate inheritance values compared to wild type strains) and removal (black bars; 100% decrease means a two-fold decrease in the inheritance values compared to wild type strains). …”

External bases do not catalyze some McLOV proteins. by Kaley K. El-Arab (733285)

“…In contrast, a Thr27Ile demonstrates spectra consistent with LOV chemistry (E) with a 100-fold decrease in the rate of adduct decay (F). …”

Elevations of HIF-1α mRNA and protein expressions by HMGB1 and their inhibition by cilostazol. by Hye Young Kim (135983)

“…(C) Time (3, 6, 12, and 24 hr)-dependent increases in HIF-1α protein levels in the presence of 100 ng/ml of HMGB1. (D) Concentration-dependent decrease of HMGB1 (100 ng/ml)-induced HIF-1α protein by cilostazol (CSZ; 1, 10 and 30 µM) and resveratrol (RES, 20 µM). …”