QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS by MARCELO PARENTE OLIVEIRA (12679956)

“…Methods: In two groups with OA, one of cadavers and another of individuals, the area of neural elements identified in histological sections of PCL with anti-S100 immunohistochemistry was quantified. Results: The overall mean area of the neural elements was 0.96% ± 0.67%, with the value in the cadaver group of 1.02% ± 0.67% and in the OA group of 0.80% ± 0.64%, with a significant statistically difference (p = 0.001). …”

EPB-113 binds to hexameric nsp15 protein. by Benjamin Van Loy (9496075)

“…<p>(A) Thermal shift assay showing the decrease in T_m when 6 µM of nsp15 protein was incubated with 100 µM EPB-113. …”

SF-E inhibits NMDA-induced ROS production without altering cell viability of primary cortical neurons. by Jinghua Jiang (527159)

“…<p>(A) Exposure of SF-E (0–7.5 µg/mL) to primary cortical neurons for 24 h did not alter neuronal viability as assayed by MTT. …”

Light-induced upregulation associates with H2Bub enrichment over transcribed regions. by Clara Bourbousse (150199)

“…(C) Time-series distribution of H2Bub levels over genes that are upregulated by light and marked at 6 h (n = 189). Mean H2Bub levels from all tiles for genes in each category were plotted on a schematized gene scaled to accommodate different transcribed region lengths (represented from 0 to 100%). …”

Comparison between α1β2γ2 and α3β2γ2 GABA-channel currents elicited by brief GABA applications by Andrea Barberis (74413)

“…Journal Compilation © Federation of European Neuroscience Societies and Blackwell Publishing Ltd</p> (A) Multiple records of 1 s illustrating channel activity evoked by 2 ms applications of GABA to outside-out patches in two patches excised from human embryonic kidney (HEK) cells expressing single α1β2γ2 (left, 10 m GABA) and α3β2γ2 (right, 50 m GABA) channels (holding potential, −100 mV). …”

HIV-1 inhibits autophagy in bystander macrophages/monocytic cells. by Jennifer Van Grol (233759)

“…HIV-1⁺ patients were classified as non-responder when their macrophages exhibited a percentage decrease in parasite load that was less than the 10^th percentile of the percentage decrease in parasite load observed in macrophages from healthy controls. …”

Disruption of EAE pathogenesis by B cell depletion. by Nancy L. Monson (121113)

“…Results shown are the mean IgG concentration +/− SEM. Asterix indicates significant decrease as compared to Rituximab-treated WTLM mice. …”

DataSheet_1_Effects of replacing fishmeal with cottonseed protein concentrate on growth performance, blood metabolites, and the intestinal health of juvenile rainbow trout (Oncorhy... by Yang Liu (4829)

“…However, reduced growth and feed intake were observed in rainbow trout fed a fishmeal-free diet based on CPC (CPC100%). Changes in serum metabolites were also observed in CPC100% compared with the control group, including an increase in alanine aminotransferase (ALT), a decrease in alkaline phosphatase (ALP), alterations in free amino acids, and reductions in cholesterol metabolism. …”

Co-immunoprecipitation of CFTR, HSPs, VCP, and HDAC6 in the N1303K and S1235R cell lines treated or untreated with the compounds. by Daniele Rapino (506785)

“…(<b>B)</b> Graphs were adjusted for the total amount of CFTR detected in the immunoprecipitated samples (the y axis shows the ratio between each sample and the total amount of CFTR in that sample. Controls are set as 100% binding). The data show that treatment with compounds C3+C4 at 5 μM is able to significantly decrease the amount of the HSPs VCP and HDAC6 that bind to the mutants. …”

Retinoic acid attenuates reductions of phospho-Akt and phospho-Bad expression due to MCAO damage. by Ju-Bin Kang (16021324)

“…Scale bar = 100 μm.</p>…”

Aortic expression of MMP-2, -3, -8 and -13 mRNA after 6 or 9 months exposure to ¹³⁷Cs. by Clélia Le Gallic (750269)

“…C and D: concerning MMP8 and MMP13, we noticed a significant decrease for ApoE^<b>-/-</b> Cs100 after 6 months exposure. …”

Effect of exercise and PCB on levels of IL-6 in wound tissue at day 3 and day 5 post-wounding. by Mahesh R. Pillai (9292269)

“…<p>In not exercised animals, on Day 3, there appears to be no difference in the means of IL-6 concentrations across PCB doses. However, Day 3, exercised animals demonstrate a pattern of reduced IL-6 concentrations with PCB 500 and PCB 1000, but increased with PCB 100 administration as compared to PCB 0. …”

Spinal cord staining with GFAP. by Dalal G. Al-Adwani (8190696)

“…<p><b>A:</b> Representative photomicrographs (100x objective) of the ipsilateral ventral grey horn of L3-L6 spinal cords sections from all groups immunostained for GFAP (GFAP (GA-5): sc-58766, Mouse Monoclonal–Santa Cruz Biotechnology) at week 3 <b>(A1, A3, A5, A7 and A9)</b> and week 6 <b>(A2, A4, A6, A8 and A10)</b> following nerve crush injury. …”

DataSheet_1_Response of harbor porpoises (Phocoena phocoena) to different types of acoustic harassment devices and subsequent piling during the construction of offshore wind farms.... by Julika Voß (14825551)

“…Depending on the wind farm, detection rates during APD operation decreased by 30 to 100% at 750 m distance compared to 6 hours before APD operation. …”

Technical and economic viability of rendering mortar produced with incorporation of ornamental rocks residue by Luís Gustavo Fiorese Vinco (4653883)

“…In this research, the mixtures that showed the best results were those with an addition of 100% of ORRC. Regarding production costs, there was a decrease in all the mixtures with the addition of ORRC. …”

The ROP2-RIC4 pathway inhibits PIN1 endocytosis through the promotion of the accumulation of cortical actin filaments. by Shingo Nagawa (173932)

“…Compared to WT cells, formation of vesicles (arrowheads) and decrease of PM signal were accelerated in <i>ric4-1</i> cells as in <i>rop4 R2i</i> cells (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001299#pbio-1001299-g001" target="_blank">Figure 1D</a>). …”

Investigating the expression of several bone markers in mineralizing 4T1 cells using real-time RT-PCR. by Rachel F. Cox (148193)

“…<p>(A) Alizarin red S and von Kossa staining of 4T1 cells after 28 days as viewed under a light microscope at 100× magnification (n = 3). …”

PGRN knockdown results in reduced motor axon outgrowth. by Angela S. Laird (360986)

“…<p>A) Knockdown of <i>grna</i>, by morpholino targeted to both the start codon (ATG) and 5′UTR region of zebrafish PGRN sequence, produced a dose dependent decrease in axonal length compared to mismatch Control MO injected embryos.…”

Statistical comparisons for the joint entropy measurements obtained from individual subjectspresented in Tables 1–3. by Vladímir de Aquino Silveira (513285)

“…In all frequencies there was a trend for joint entropy to decrease when contrast was increased, but this reached the level of statistical significance only for the comparison between 5% and 100% contrasts (p<0.05; One-Way ANOVA, Tukey Multiple Comparison Test). …”

Propagation of GABA-induced hyperpolarization at the axon regulates AP generation. by Yang Xia (104600)

“…Right, group data showing a decrease in the mean frequency of APs after GABA iontophoresis at the axon trunk. **, P<0.01, paired t-test. …”