Effect of SRF on the activity of CArG-containing minimal promoter by Céline René (10829)

“…Densitometric analysis showed a substantial decrease of endogenous SRF. Right panel: the luciferase activity value 100 was assigned to the samples co-transfected with the control siRNA. *, < 0.05 versus WT or 3XSRE.…”

Pcl3 promotes ESC self-renewal. by Julie Hunkapiller (177548)

“…Graph represents average expression from 3–6 different clones. (B) A portion of cells transduced with <i>Pcl3</i> shRNA, but not scramble shRNA, are larger, flatter, and less dense, signifying a decrease in ESC cell morphology. …”

Upper extremity orthopedic softball injuries presenting to the emergency department: epidemiology across the lifespan by David F. Painter (12884672)

“…The average incidence rate of UE injuries from 2012–2021 was 187.9 per 100,000 persons, with a significant decrease in injury incidence across the timespan (<i>p</i> < .001). …”

ErbB signaling is implicated in generation of neurons and mitoses in the sub-ventricular zone. by Tomomi Sato (301255)

“…Impaired neurogenesis and a decrease in pH3-positive mitotic cells in the SVZ of AG1478-treated Tg(<i>pou4f1-hsp70l</i>:<i>GFP;-8</i>.…”

Determination of mitochondrial temperature in intact human cells. by Dominique Chrétien (217681)

“…The MTY fluorescence reached at the end of phase I was significantly different (<i>n</i> = 10; ***) from the starting value of 50%, whilst the final value in phase IV was not. (D) (a) Linear increase of fluorescence of HEK293 cells (preloaded for a minimum of 10 min, with 100 nM MTY), according to cell number (using cell protein concentration as surrogate parameter); (b) Maximal rate of decrease of MTY fluorescence (percentage, blue circles, corresponding with mitochondrial warming) is not significantly affected by cell number, whereas initial fluorescence increase in the presence of cyanide (percentage, green circles, corresponding with initial rate of mitochondrial cooling) is modulated by cell number (values at the three cell concentrations tested were significantly different from each other). …”

Table_2_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Table_1_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Table_6_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Table_4_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Image_1_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.tif by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Table_7_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Table_5_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Table_3_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Supplementary material: Evaluation of emerging NASH therapies: the impact of treatment efficacy profiles on long-term health outcomes by William Herring (18495130)

“…Hypothetical efficacy profiles were defined affecting resolution (100%-increase), fibrosis improvement (100% increase), or fibrosis worsening (50% decrease). …”

Table 1_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…</p>Findings<p>Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367–179,472,942), 305,596 deaths (95% UI: 240,004–365,146), and 28,410,167 DALYs (95% UI: 23,100,433–33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. …”

Table 3_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…</p>Findings<p>Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367–179,472,942), 305,596 deaths (95% UI: 240,004–365,146), and 28,410,167 DALYs (95% UI: 23,100,433–33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. …”

Data_Sheet_1_Mechanism of fungal remediation of wetland water: Stropharia rugosoannulata as promising fungal species for the development of biofilters to remove clinically importan... by Keya Sen (2223421)

“…Percent remediation varied as follows: S. aureus-100%, E. faecium-97%, C. jejuni-59%, P. aeruginosa-54%, E. coli-65% and S. enteritidis-27%. …”

Data_Sheet_1_Mechanism of fungal remediation of wetland water: Stropharia rugosoannulata as promising fungal species for the development of biofilters to remove clinically importan... by Keya Sen (2223421)

“…Percent remediation varied as follows: S. aureus-100%, E. faecium-97%, C. jejuni-59%, P. aeruginosa-54%, E. coli-65% and S. enteritidis-27%. …”

Image 1_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.tif by Wei Wei (21173)

“…</p>Findings<p>Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367–179,472,942), 305,596 deaths (95% UI: 240,004–365,146), and 28,410,167 DALYs (95% UI: 23,100,433–33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. …”

Data_Sheet_1_Mechanism of fungal remediation of wetland water: Stropharia rugosoannulata as promising fungal species for the development of biofilters to remove clinically importan... by Keya Sen (2223421)

“…Percent remediation varied as follows: S. aureus-100%, E. faecium-97%, C. jejuni-59%, P. aeruginosa-54%, E. coli-65% and S. enteritidis-27%. …”