Selective Blockade of Trypanosomatid Protein Synthesis by a Recombinant Antibody Anti-<em>Trypanosoma cruzi</em> P2β Protein by Maximiliano Juri Ayub (166808)

“…<div><p>The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against the C-terminal region of the <em>Trypanosoma cruzi</em> P2β protein (TcP2β) recognizes the conserved C-terminal end of all <em>T. cruzi</em> ribosomal P proteins. …”

Functional E2F sites in the Kpnβ1 (−637 to −271) and Kpnα2 (−180 to −24) promoter regions contribute to high promoter activity in transformed and cancer cells. by Pauline J. van der Watt (339036)

“…Mutation of the three distal E2F sites lead to a significant decrease in Kpnβ1 (−637 to +100) promoter activity, as indicated by luciferase assays. …”

Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations by Yan Xu (14594)

“…In addition to the knotted conformation, dimerization further improves the protein stability by restricting the α1−α5 separation, which is defined as a leading step for protein unfolding. …”

Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations by Yan Xu (14594)

“…In addition to the knotted conformation, dimerization further improves the protein stability by restricting the α1−α5 separation, which is defined as a leading step for protein unfolding. …”

Foot-off times from the 1, 2(an hour later) and 3(a week later) test session for the elderly and younger group of subjects, respectively, across 6 trials and Task conditions: singl... by Itshak Melzer (75733)

<i>klf4</i> is required for the maintenance of the <i>egc</i>^<i>+</i><i>/meg-1</i>^<i>+</i><i>/zfp-1-1</i>^<i>+</i> TRL. by Lu Zhao (296389)

“…(F) FISH depicting a modest decrease in <i>tsp-2</i>⁺ cell number following <i>klf4</i> RNAi. …”

Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR-3 by Aiala Lorente (88690)

“…As the % of methylated DNA increases (0%, 5%, 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90% and 100%) the peak appears higher. Measuring the height of the peak of each sample, and interpolating the data in the graph, we can obtain an approximate % of fully methylated DNA present in each sample.…”

Table_1_Production, Storage Stability, and Susceptibility Testing of Reuterin and Its Impact on the Murine Fecal Microbiome and Volatile Organic Compound Profile.docx by Christoph Castellani (5940710)

“…In the fecal, VOC analysis decreased heptane and increased 3-methylbutanal were encountered. …”

Image_1_Production, Storage Stability, and Susceptibility Testing of Reuterin and Its Impact on the Murine Fecal Microbiome and Volatile Organic Compound Profile.pdf by Christoph Castellani (5940710)

“…In the fecal, VOC analysis decreased heptane and increased 3-methylbutanal were encountered. …”

Table_1_A cost-effectiveness analysis of pre-pregnancy genetic screening for deafness: an empirical study in China.DOCX by Yipeng Lv (2578990)

“…We compared the cost-effectiveness of deafness genetic screening with the status quo. The two-step screening (wife then partner) and following treatments and interventions were included in the decision tree model. …”

Regulation by a shared sRNA synchronizes the temporal induction of mRNA expression. by Jörn Matthias Schmiedel (141779)

“…The heatmaps show simulation results for a regulatory scenario where a coordinate, step-like increase (C) or decrease (panel D) in both mRNA synthesis rates is accompanied by a step-like change in the sRNA synthesis rate in the opposite direction; this counter-regulation assumption was necessary to eliminate delay phases, and to obtain the same steady states in sRNA and sRNA-less systems. …”

HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an study-1 by Ling Bai (82594)

“…However, treatment with 100 nM Tat(■) induced a significant decrease in the TER beginning at 3 hours, with a further decrease at 12 hours and a maximum effect at 24 hours, which was maintained to 72 hours. …”

TnIc G4s unfolding curves and corresponding fitted curves. by Wenhua Zhou (104668)

“…<p>(<b>a</b>) Decrease of Cy5 fluorescence in the process of MNSG4 (formed between oligos <b>Tr_MNS-III</b> and <b>Comp-Cy5</b>) opened by its C-rich complimentary strand (oligo <b>Tr_MNS-II</b>) at different temperature. …”

MUI and TSH relationship in 4 groups of population. by Fangang Meng (144470)

“…The TSH value was spotted to decrease and subsequently increase with an elevation in MUI, and formed a “U curve” relationship in children, adults and pregnant women except in lactating women. …”

Cell loss is further exacerbated in E11.5 <i>Sphk1−/−;Sphk2−/−</i> trigeminal ganglion. by Hui Meng (197494)

“…<b>^††</b> = <i>Sphk1−/−;Sphk2−/−</i> to <i>Sphk1−/−;Sphk2+/−</i> comparison, p<0.01; <b>^##</b> = <i>Sphk1−/−;Sphk2+/−</i> to wild type comparison, p<0.01. <b>Scalebar</b> for A–F = 100 µm.</p>…”

Data Sheet 1_Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.csv by Lihong Huang (1346928)

“…</p>Results<p>Globally, the age-standardized rates of refractive disorders per 100,000 population decreased in all age groups from 1990 to 2021. …”

Table_1_Lipoamide Alleviates Oxidized Fish Oil-Induced Host Inflammatory Response and Oxidative Damage in the Oviduct of Laying Hens.docx by Qingxiu Liu (739695)

“…Therefore, in the current study, to investigate the effects of LAM in alleviating OFO-induced decline in reproductive performance and oxidative damage to the oviduct in laying hens. We constructed a 1% fresh FO model, a 1% OFO model, and a LAM model with 1% OFO (OFO + LAM) added at 100 mg/kg to explore the antioxidant effect of LAM. …”

Table 1_Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.xlsx by Lihong Huang (1346928)

“…</p>Results<p>Globally, the age-standardized rates of refractive disorders per 100,000 population decreased in all age groups from 1990 to 2021. …”

Table 2_Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.xlsx by Lihong Huang (1346928)

“…</p>Results<p>Globally, the age-standardized rates of refractive disorders per 100,000 population decreased in all age groups from 1990 to 2021. …”

Data Sheet 2_Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.csv by Lihong Huang (1346928)

“…</p>Results<p>Globally, the age-standardized rates of refractive disorders per 100,000 population decreased in all age groups from 1990 to 2021. …”