Enhanced intrinsic excitability of spinal Calcrl⁺ neurons in chronic itch. by Huifeng Jiao (11537806)

“…Unchanged maximal rise slope <b>(G)</b>; Reduced half-width <b>(H)</b>; Decreased AHP amplitude <b>(I)</b>; Increased number of spikes upon 100 pA depolarization <b>(J)</b>. …”

Penile cancer trends and economic burden in the Brazilian public health system by Fernando Korkes (5910167)

“…Conclusion: Despite the decrease in admissions, penile cancer still imposes a significant economic and social burden to the Brazilian population and the Public Health System.…”

cAMP dynamics in adult mouse ventricular Epac1-camps expressing cardiomyocytes upon treatment with cAMP elevating agents and PDE4 inhibition. by Julia U. Sprenger (3387719)

“…<b>(C)</b> Representative FRET traces from Epac1-camps cardiomyocytes stimulated with the β-AR agonist isoproterenol (ISO, 100 nM) or <b>(E)</b> with the direct AC activator forskolin (10 μM) leading to an increase of cAMP visualized as a decrease in the FRET ratio. …”

Astrocytic volume changes in the cortex of GFAP/EGFP and GFAP/EGFP/α-Syn^−/− mice during hypoosmotic stress. by Miroslava Anderova (155561)

“…The changes of astrocytic volume during washout were evaluated in each individual cell and expressed as an average percent of cell volume increase/decrease related to the maximal volume after 30 minutes of aCSF_H-50 (<b>C right</b>) or aCSF_H-100 (<b>D right</b>) exposure; these values were set as 0%. …”

Validation of the primary screen hits with secondary luciferase-based invasion and red-green invasion assays. by Rajshekhar Y. Gaji (417441)

“…The values obtained with non-targeting siRNA controls were set at 100% invasion. A total of 81 genes (red asterisks) showed significant decrease (<i>p</i><0.05, one sample <i>t</i>-test) in parasite invasion compared to NTsiRNA controls. …”

Expression of MMP7 and TIMP1 in wounds. by Katharina Sommer (463202)

“…Septic animals show a significant decrease in MMP7 expression on day 2 and 6 compared to control mice. …”

Ca²⁺ sparklets in DSM are affected by, but not dependent upon, signals from the SR. by Peter Sidaway (190696)

“…In the presence of the VGCC antagonist R-(+)-Bay K 8644 (1 μM) and CPA (10 μM), there was a significant decrease in the frequency (D) but not amplitude (E) of Ca²⁺ sparklets. …”

Glycosylation inhibitors block thrombin-induced sRBC adhesion to HUVECs. by Pushpankur Ghoshal (580530)

“…The level of sRBC adhesion to untreated HUVECs was set to 100%. **, p<0.0001 <b>B</b>. Glycosylation inhibitors decrease thrombin-induced sRBC adhesion to HUVECs. …”

Transcripts differentially expressed in response to overexpression of and in response to overexpression of human , grouped according to functional classes by Haiqiong Montalta-He (54730)

“…Positive values indicate that the relative expression level of a gene is increased (upregulated) following overexpression and negative values indicate a decrease (downregulated). …”

Anti-HBV activity of CDM-3008 in primary cultured human hepatocytes. by Yutaka Furutani (5620139)

“…(C) Measurement of HBV DNA copies in PXB cells after 7 days of CDM-3008 treatment. HBV DNA was decreased with 0.1–100 μM CDM-3008 in a dose-dependent manner. …”

Histology of islet allografts at day 10, 17, 24, and 31 after transplantation in non-diabetic mice. by Jyuhn-Huarng Juang (407970)

“…There was profound immune cell infiltration at day 10 and 17, and a decrease in graft size at day 24 and 31 in the CSPIO-labeled islet graft. …”

Gene expression in primary human skeletal muscle cells after treatment with acylcarnitines. by Rainer Lehmann (141280)

“…<p>mRNA expression of PGC-1α (A), CPT1b (B), CD36 (C), COX1 (D) and AngPL-4 (E) related to β-actin mRNA levels after incubation with 100 µM L-carnitine (L-C), an equimolar mixture of C8:0-, C10:0- and C12:0-acylcarnitine (total 100 µM; AC), 60 µM palmitate (p), or p and AC as indicated. …”

Effect of galactose treatment on oleic acid metabolism. by Eili Tranheim Kase (177084)

“…Suppressibility, defined as the ability of the cells to decrease oleic acid oxidation by acutely added glucose, was calculated as: [(1-(oxidation of oleic acid at 5 mM glucose/oxidation of oleic acid at no glucose added))×100%]. …”

Hormone addition results in chromatin changes at individual GR-regulated genes. by Chuong D. Pham (111374)

“…We calculate that a nucleosome/bare ratio of 1.0 corresponds to ∼50% nucleosome occupancy, while a value of 2.1 corresponds to 100% occupancy (e.g. a nucleosome covering a given location on all gene copies). …”

The effect of ribavirin (Rib) and guanosine (Gua) on HCV infectious progeny production and intracellular viral RNA and nucleotide pools. by Ana M. Ortega-Prieto (446894)

“…(c) Left: intracellular amount of the four nucleoside-triphosphates, following 72 h of exposure to either Rib or Gua, as indicated at the bottom. Right: decrease or increase of nucleotide concentration as a result of exposure to Gua or Rib; note that the maximum decrease possible is 100%. …”

K_v4 is Required for Maintaining Excitability in <i>Drosophila</i> Neurons. by Yong Ping (233004)

“…<p><i>A</i>, Representative firing patterns recorded with current injections of 40, 60, and 100 pA from wild-type (wt) and DNK_v4 (DN) neurons. …”

Metabolic profiling by tandem mass spectrometry reveals distinct metabolite signatures of cells exposed to pro-inflammatory cytokines vs. the apoptotic inducer camptothecin. by J. Jason Collier (130356)

“…<p><i>A</i>. 832/13 cells were exposed to 1 ng/mL IL-1β+100 U/mL γ-IFN or 2 µM camptothecin for 6 h. …”

Fasting Conceals Rapid Diet-Induced Inhibition of PDH. by Clair Crewe (467358)

“…Mitochondria were incubated with 100 µM pyruvate and 1.0 mM malate. State 3 respiration was initiated by addition of 0.25 mM ADP. …”

Ketamine reduces cell adhesion. by Claire E. Hills (452020)

“…<p>AFM-single-cell force spectroscopy was used to measure the detachment energy (fJoules) and maximum unbinding force (nN) required to uncouple two HK2 cells. The energy required to separate the cells; grey area in panel A (control cells), panel B (0.1 mg/mL Ketamine treated cells), panel C (0.5 mg/mL Ketamine treated cells), and panel D (1 mg/mL Ketamine treated cells), and maximum force of detachment (red circle) was measured. …”

Supplemental Figure 1 by Wolfgang Stein (11859731)

“…(i) The LG membrane potential was hyperpolarized from -50 mV to -80 mV. (ii) The LG membrane potential was depolarized from -80 mV to -50 mV. …”