Combined Delivery of Paclitaxel and Tanespimycin via Micellar Nanocarriers: Pharmacokinetics, Efficacy and Metabolomic Analysis by Usha Katragadda (386668)

“…The goal of this study was to evaluate a micellar formulation for the concurrent delivery of paclitaxel and 17-AAG <i>in vivo</i>.…”

Azocyclotin Binds CDK4 to Disrupt DNA Methylation in Zebrafish Epigenetic Transgenerational Inheritance by Aoxue Wang (275954)

“…Using zebrafish ZF4 cells as an <i>in vitro</i> model, we elucidated the mechanism by which ACT modulates DNA methylation. ACT exposure induced a 38.03% decrease in global DNA methylation, as determined by 5-mC quantification. …”

Image_1_SIRT6 Inhibitor, OSS_128167 Restricts Hepatitis B Virus Transcription and Replication Through Targeting Transcription Factor Peroxisome Proliferator-Activated Receptors α.t... by Hui Jiang (102809)

“…Firstly, we found that OSS_128167 could decrease the level of HBV core deoxyribonucleic acid (DNA) and 3.5-Kb ribonucleic acid (RNA) in vitro. …”

Effect of bone morphogenetic protein-2 (BMP-2) overexpression on mRNA levels of extracellular matrix molecules and proteoglycan (PG) synthesis by Esmeralda N Blaney Davidson (39198)

“…<p><b>Copyright information:</b></p><p>Taken from "Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling"</p><p>http://arthritis-research.com/content/9/5/R102</p><p>Arthritis Research & Therapy 2007;9(5):R102-R102.…”

Interactions between Silicon Oxide Nanoparticles (SONPs) and U(VI) Contaminations: Effects of pH, Temperature and Natural Organic Matters by Hanyu Wu (694635)

“…However, an irreversible interaction of U(VI) was observed in the presence of HA (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0149632#pone.0149632.g001" target="_blank">Fig 1</a>). …”

Image_4_Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea.jpeg by Andrea Pagano (7845914)

“…</p>Results and discussion<p>After 3 weeks of recovery from zebularine treatment, a decrease of 5-mC levels was observed in different genomic contexts in the roots of explants that were exposed to zebularine, whereas a functionally heterogeneous subset of protein entries was differentially accumulated in stem samples, including entries related to cell wall biosynthesis, tissue morphogenesis, and hormonal regulation. …”

Effect of different concentrations of dietary safflower seed on milk yield and some rumen and blood parameters at the end stage of lactation in dairy cows by Mustafa Numan Oguz (12800989)

“…Cows were fed 8 kg concentrate, 2 kg wheat straw, and corn silage ad libitum(approximately 20 kg). Diet S-III caused a decrease in efficiency of milk production and diet S-II provided a much further efficiency in milk production (C = 13.39±0.23, S-I = 12.94±0.26, S-II = 13.46±0.24 and S-III = 11.83±0.52 kg). …”

Image_6_Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea.png by Andrea Pagano (7845914)

“…</p>Results and discussion<p>After 3 weeks of recovery from zebularine treatment, a decrease of 5-mC levels was observed in different genomic contexts in the roots of explants that were exposed to zebularine, whereas a functionally heterogeneous subset of protein entries was differentially accumulated in stem samples, including entries related to cell wall biosynthesis, tissue morphogenesis, and hormonal regulation. …”

Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane by Vasavi, Boggarapu

“…In addition, Differential scanning calorimetry (DSC)exhibited a decrease in glass transition temperature (Tg) from S1 to S10, resulting in a corresponding reduction in the rate of shape restoration. …”
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Deficiencies of TWEAK attenuate NF-ĸB2 activation in the RNA toxicity mice. by Ramesh S. Yadava (2268922)

“…<p>(A) Immunofluorescence shows decreased NF-ĸB2 in skeletal muscle from DM5/<i>Tweak</i>^<i>-/-</i> D+ mice as compared to DM5/<i>Tweak</i>^<i>-+/+</i> D+ mice. …”

Suppression of GLIPR-2 expression attenuates ERK1/2 activation, EMT-like phenotype following by migration and invasion in response to hypoxia. by Shao-guang Huang (477673)

“…<p>(A) GLIPR-2, p-ERK1/2 and EMT markers expression in HepG2 and <i>PLC</i>/PRF/5 cells after suppression of GLIPR-2 after hypoxia 48 h. …”

Activity profiles of regions involved in 3D SfT. by Koen Nelissen (256126)

“…<p>Percent signal change from fixation baselines is plotted as a function of condition for left and right V2/V3, (ventral) TEO, CIP, anterior LIP, and AIP. …”

S1 Raw image - by Darshika Udari Hettiarachchi (18784440)

“…Thereafter, fluorescent cell and cluster area in the host declined with no further decrease after 10 DPH. At 45 DPH, the highest percentage of xenogens were detected when fry were injected with BSCs between 4.0 to 5.0 and CSCs between 3.0 to 5.0 DPH. …”

Phase decomposition of the re-exposure behaviours. by Pengxing Cao (615266)

“…Phase 4 (blue) is the final period where both viruses are neutralised by their specific antibodies. A scale bar of 5 days indicates the length of time.…”

The experimental schedules. by Hiroharu Maegawa (8087543)

“…At 7 days post-ligation, a nerve-ligated rat with a decrease in the head-withdrawal threshold (a rat with chronic constriction injury of the ION: ION-CCI rat) underwent a metal cannula implantation. …”

Igf signaling is required for cardiomyocyte proliferation during zebrafish heart regeneration. by Ying Huang (53474)

“…<i>Tg(hsp70:gal4)</i> control (n = 5) (A, A’, A’’) and <i>Tg(hsp70:dnigf1ra-GFP)</i> transgenic zebrafish (n = 7) (B, B’,B’’) zebrafish were heat shocked for 1 h at 38°C after amputation from 2–10 dpa. …”

Data_Sheet_1_Air pollution exposure and pregnancy outcomes among women with polycystic ovary syndrome.docx by Qianqian Zhu (48100)

“…Each IQR increase in SO₂ among patients without PCOS during periods 1 (start of gonadotropin medication to oocyte retrieval), 2, 5, and 6 (start of gonadotropin medication to serum HCG test) was related to a decrease in clinical pregnancy rate. …”

CV1720 cells show impaired ATR–dependent DNA damage responses. by Tomoo Ogi (122258)

“…<p>A) WT, DK0064 (ATR–SS), CV1720 (patient), CV1780 (patient's mother) and CV1783 (patient's father) cells were exposed to 5 Jm⁻² UV and the mitotic index (MI) assessed 2 h post exposure. …”

Electromyographic analysis of postural overload caused by bulletproof vests on public security professionals by Michele Caroline dos Santos (5609945)

“…Conclusion The used protocol highlighted a decrease in the amplitude of the electromyographic signal, as well as possible muscle fatigue on the right side where officers usually carry their weapons.…”

Loss of <i>bmm</i> in the neurons with an independent RNAi line has no effect on triglyceride storage or breakdown in females. by Lianna W. Wat (8339454)

“…(F) Triglyceride breakdown post-starvation was modestly decreased by a similar magnitude among genotypes in 5-day-old virgin <i>nSyb>UAS-bmm-RNAi</i> females and control females (<i>nSyb>+</i> and <i>+>UAS-bmm-RNAi</i>) between 0 and 12 hours STV (<i>p</i> = 0.21, 0.017, and 0.43, respectively; one-way ANOVA followed by Tukey HSD test). …”