Video_6_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…<p>Women acquire HIV through sexual transmission, with increasing incidence in women >50 years old. Identifying protective mechanisms in the female genital tract (FGT) is important to prevent HIV-acquisition in women as they age. …”

Image_3_Alterations of Gut Microbiome and Metabolite Profiles Associated With Anabatic Lipid Dysmetabolism in Thyroid Cancer.tif by Ganghua Lu (12750878)

“…</p>Methods<p>16S rRNA gene sequencing and an integrated LC–MS-based metabolomics approach were performed to obtain the components and characteristics of fecal microbiota and metabolites from 50 patients with TC and 58 healthy controls (HCs).…”

Image_2_Altered Intra- and Inter-Network Connectivity in Drug-Naïve Patients With Early Parkinson’s Disease.TIF by Weiqi Zeng (4386472)

“…Additionally, our results support PD as a disconnection syndrome.</p>…”

The Effect of Garlic and Voluntary Exercise on Cardiac Angiogenesis in Diabetes: The Role of MiR-126 and MiR-210 by Roya Naderi (6098570)

“…On the other hand, there was a miR-210 expression increase in the myocardium of diabetic animals (p < 0.001). …”

Early CD8⁺-recovery independently predicts low probability of disease relapse but also associates with severe GVHD after allogeneic HSCT by Juha Ranti (5774918)

“…We found that CD8⁺ T-cell counts exceeding 50x10⁶/l as early as on day 28 post-transplantation correlated significantly with decreased relapse risk, with three-year relapse rates of 17.0% and 55.6% (P = 0.002), but were also associated with severe acute and chronic GVHD. …”

The NAD⁺ that is spontaneously released from M-MSNs@NAD⁺ can not increase the intracellular NAD⁺ and ATP levels in H₂O₂-treat... by Heyu Chen (456225)

“…<p>(A) The concentration of NAD⁺ that was spontaneously released from the 50 µg/mL M-MSNs@NAD⁺ into the media. …”

Image_3_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

Image_1_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

Table_7_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Table_1_Clinical study on endovascular recanalization of non-acute symptomatic middle cerebral artery occlusion.XLSX by Jinchao Xia (14211707)

“…From the low- to high-risk groups, the recanalization rate gradually decreased (100.0, 91.7, and 16.7%, respectively, P = 0.020), the perioperative complication rate gradually increased (0, 13.9, and 83.3%, respectively, P < 0.001), the proportion of the modified Rankin scale scores >2 at 90 days increased (0, 11.7, and 50.0%, P < 0.001), and the restenosis/reocclusion rates in the 73 cases of successful recanalization increased (0, 16.1, and 100%, P = 0.012) during follow-up.…”

DataSheet_1_The Hypoglycemic and Renal Protection Properties of Crocin via Oxidative Stress-Regulated NF-κB Signaling in db/db Mice.docx by Ye Qiu (363315)

“…</p>Methods<p>Eight-week-old db/db mice were treated with metformin (Met) (100 mg/kg) and CR (50 mg/kg) for eight weeks.</p>Results<p>CR treatment showed hypoglycemic functions indicated by reduced bodyweight, food and water intake, plasma glucose, and serum levels of glycated hemoglobin A1c. …”

Video_3_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…<p>Women acquire HIV through sexual transmission, with increasing incidence in women >50 years old. Identifying protective mechanisms in the female genital tract (FGT) is important to prevent HIV-acquisition in women as they age. …”

Table_1_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.docx by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

DataSheet_1_Changing trends in the disease burden of uterine cancer globally from 1990 to 2019 and its predicted level in 25 years.docx by Shuang Song (457799)

“…</p>Conclusions<p>UC has significantly impacted global health negatively, with its influence stemming from a range of factors including geographical location, age-related and racial disparities, and SDI.…”

Table_2_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Table_4_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Image_1_Alterations of Gut Microbiome and Metabolite Profiles Associated With Anabatic Lipid Dysmetabolism in Thyroid Cancer.tif by Ganghua Lu (12750878)

“…</p>Methods<p>16S rRNA gene sequencing and an integrated LC–MS-based metabolomics approach were performed to obtain the components and characteristics of fecal microbiota and metabolites from 50 patients with TC and 58 healthy controls (HCs).…”

Data Sheet 1_Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats.docx by Baocang Yin (20689031)

“…Ethnopharmacological relevance<p>Eucommia ulmoides, recognized as a traditional Chinese medicinal herb, can tonify liver and kidney and strengthen bones and muscles. …”

Chlorogenic Acid Combined with <i>Lactobacillus plantarum</i> 2142 Reduced LPS-Induced Intestinal Inflammation and Oxidative Stress in IPEC-J2 Cells by Orsolya Palócz (3353603)

“…Treatment with chlorogenic acid (25–50 μM) significantly decreased gene expression and concentration of proinflammatory cytokines IL-6 and IL-8 compared to LPS-treated cells. …”

Functional and Structural Succession of Soil Microbial Communities below Decomposing Human Cadavers by Kelly L. Cobaugh (753944)

“…During active decay (7 - 12 days postmortem), respiration and biomass production rates were high: the community was dominated by Proteobacteria (increased from 15.0 to 26.1% relative abundance) and Firmicutes (increased from 1.0 to 29.0%), with reduced Acidobacteria abundances (decreased from 30.4 to 9.8%). Once decay rates slowed (10 - 23 d postmortem), respiration was elevated, but biomass production rates dropped dramatically; this community with low growth efficiency was dominated by Firmicutes (increased to 50.9%) and other anaerobic taxa. …”