Screening TAS2R5 agonists for the receptor downregulation response to long- term agonist exposure. by Donghwa Kim (252081)

“…<p>HEK-293T cells stably expressing FLAG-tagged TAS2R5 were exposed in culture for 18 hrs to the indicated agonists at a concentration 10-fold greater than their functional EC₅₀ values. …”

Contribution of anti-MPER antibodies to the plasma's cross-neutralizing activities. by Iliyana Mikell (120166)

“…</p>d<p>The neutralizing activities of plasmas collected at the indicated time points following infection were evaluated against the HIV-1 viruses JRFL and TRO.11 in the absence or presence of the MPER peptide (NEQELL<u>ELDKWASLWNWFDITN</u>WLWYIRKKK). The Log10 decrease in IC50 neutralization titers in the presence of the MPER peptide is indicated.…”

Image_3_Plasmodium berghei Kinesin-5 Associates With the Spindle Apparatus During Cell Division and Is Important for Efficient Production of Infectious Sporozoites.tif by Mohammad Zeeshan (9517067)

Current distribution pattern of biopsy-proven glomerular disease in Salvador, Brazil, 40 years after an initial assessment by Washington Luis Conrado dos-Santos (12731231)

Cytotoxicity profiles of multi-walled carbon nanotubes with different physico-chemical properties by Katsuhide Fujita (2902233)

“…Rigid, needle-shaped MWCNTs with a large diameter (>50 µm) penetrated the cytoplasm and decreased cell survival without generating intracellular reactive oxygen species (ROS), significantly up-regulated many genes involved in inflammatory responses, response to oxidative stress and apoptosis, and extracellular matrix degradation. …”

Time Since Deposition Signatures for the Analysis of Canine Body Fluid by Alysia Townsley (20673209)

“…<p dir="ltr">Although dogfighting is a felony in all 50 states, it has grown into a substantial enterprise that is often tied to other organized crime activities including gambling, narcotics, and weapons trafficking. …”

Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study by Daiane Dias Ferreira (6044783)

“…Considering the mammalian cytotoxicity, the drug resulted in a selectivity index of 17.8. Sertraline induced a change in the mitochondrial integrity of T. cruzi, resulting in a decrease in ATP levels, but not affecting reactive oxygen levels or plasma membrane permeability. …”

Under-Dominance Constrains the Evolution of Negative Autoregulation in Diploids by Alexander J. Stewart (392679)

Model for Condensin II–mediated chromosome territory formation. by Christopher R. Bauer (139136)

Exploring <i>in vitro</i> anticancer potential of <i>Ferula gummosa</i> gum on PC-3 cells: insights from cellular and molecular studies by Negar Abdollahzadeh (20507068)

“…Alongside this, we observed a decrease in intracellular ROS levels and a weakening of the mitochondrial membrane potential. …”

TPEN effects on <i>C</i>. <i>elegans</i> metal content and lifespan are zinc-specific. by Jitendra Kumar (144555)

Modeling of <i>In-Utero</i> and <i>Intra-Partum</i> Transmissions to Evaluate the Efficacy of Interventions for the Prevention of Perinatal HIV by Patumrat Sripan (741310)

“…</p><p>Trial Registration</p><p>This analysis is based on secondary data obtained from three clinical trials. ClinicalTrials.gov. <a href="https://clinicaltrials.gov/ct2/show/NCT00386230" target="_blank">NCT00386230</a>, <a href="https://clinicaltrials.gov/ct2/show/NCT00398684" target="_blank">NCT00398684</a>, <a href="https://clinicaltrials.gov/ct2/show/NCT00409591" target="_blank">NCT00409591</a>.…”

Schematic description of integrating a small example metabolic network with gene expression data. by Xin Fang (134979)

“…We then minimized the modifications in the biomass objective function and those in the upper limits of metabolite uptakes (medium priority), and, last, we minimized and maximized each reaction flux (lowest priority). Finally, in Step V, we constructed the new metabolic state by calculating the new average normalized flux for each reaction as the mean of its new minimum and maximum fluxes. …”

Long Coherence Times in Nuclear Spin-Free Vanadyl Qubits by Chung-Jui Yu (3287013)

Induction of <i>ilys-3</i> requires ERK. by Maria João Gravato-Nobre (2941827)

“…Mean values for <i>mpk-1</i> mutants on CBX102 were not significantly different from their sibling controls on OP50 (<i>p</i> = 0.6098). …”

Data_Sheet_1_Spatial Distribution and Abundance of Mesopelagic Fish Biomass in the Mediterranean Sea.DOCX by Morane Clavel-Henry (8374848)

Cytotoxicity of curcubitacin B on cancer and normal human cells. by Kejuan Li (2580184)

Table_6_Dietary Supplementation With Creatine Pyruvate Alters Rumen Microbiota Protein Function in Heat-Stressed Beef Cattle.DOC by Yanjiao Li (763187)

Histologic parameters increase in proportion to podocyte depletion. by Larysa Wickman (3169548)

“…<p><b>Panel A:</b> The proportion of histologically detectable abnormal glomeruli present in a biopsy increases linearly in relation to the decrease in podocyte number per glomerulus after approximately 30% of podocytes have been lost. …”

Table_5_Dietary Supplementation With Creatine Pyruvate Alters Rumen Microbiota Protein Function in Heat-Stressed Beef Cattle.DOC by Yanjiao Li (763187)