DataSheet_2_Unveiling drug-tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis.xlsx by Marlene Jara (774474)

“…</p>Results and discussion<p>We demonstrated in vitro that a variable proportion of cells remained viable, showing all the criteria of DT and not of DR: i) signatures of quiescence, under drug pressure: reduced proliferation and significant decrease of rDNA transcription; ii) reversibility of the phenotype: return to low IC₅₀ after removal of drug pressure; and iii) absence of significant genetic differences between exposed and unexposed lineages of each strain and absence of reported markers of DR. …”

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx by Bhavana Bhatnagar (11016429)

“…Three heavily treated relapsed/refractory AML patients with FLT3-ITD were treated with TP-0903 50 mg daily, on a phase 1b/2 clinical trial, for as long as disease response or clinical benefit was observed. …”

Effect of rotenone on the striatum, VTA, and SNc TH immunoreactivity. by Nian Xiong (218611)

“…The TH immunoreactivity on the ipsilateral side of the striatum was decreased by 66.4% (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007878#pone-0007878-g004" target="_blank">Figure 4I–J</a>; *P<0.05, as compared to the contralateral side). …”

Image_1_Habenular Involvement in Response to Subcallosal Cingulate Deep Brain Stimulation for Depression.TIF by Gavin J. B. Elias (12044813)

“…Clinical response to treatment (≥50% decrease in HAMD-17 from baseline to 12 months post-operation) was significantly associated with longitudinal Hb volume change: responders tended to have increased Hb volume over time, while non-responders showed decreased Hb volume (t = 2.4, p = 0.021). …”

Data_Sheet_1_Cu5FeS4 Nanoparticles With Tunable Plasmon Resonances for Efficient Photothermal Therapy of Cancers.docx by Lei Yuan (713591)

“…After surface modification with polyethylene glycol (PEG), the CFS nanoparticles with a plasmon resonance absorption peak at 764 nm can serve as promising photothermal agents, showing good biocompatibility and excellent photothermal performance with a photothermal conversion efficiency of up to 50.5%, and are thus used for photothermal therapy of cancers under the irradiation of an 808-nm laser. …”

Glycine negatively influences THN migration. by Ulrike Theisen (4734555)

“…Means ± SEM are plotted per 10% MHB bin. (D) Statistic analysis confirms that the effects on THN migration speeds induced by glycine occur in the central region of the MHB and depend on the glycine receptor; control values from experiment shown in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2002226#pbio.2002226.g004" target="_blank">Fig 4D</a>. …”

Schematic representation of the TRA/TRD locus use. by Florence Thuderoz (366862)

“…<p>The scheme shows the rearrangement distribution of 4 V genes with all J genes. The dashed red arrow indicates the decreasing frequency of rearrangements which correlates with the associations of distal V and J genes. …”

Mutation of the hydrophobic tip residues disrupts evoked transmitter release. by Matthew R. Bowers (8423115)

“…<p>The single hydrophobic mutation decreased neurotransmitter release by 50% while the double mutation inhibited release to a greater extent than that seen in <i>syt^null</i> mutants. …”

Comparison of whole genome prediction accuracy across generations using parametric and semi parametric methods by Abbas Atefi (10414497)

“…The genome comprised one chromosome of 100 cM length carrying 50 QTLs. There was no significant difference between accuracy of investigated methods (p > 0.05) but among three methods, the highest mean accuracy (0.659) was observed for BayesA. …”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

Effect of hydrogen on CS-induced <i>muc5ac</i> expression in rat lung tissues. by Yunye Ning (500228)

“…<p>(a) Effect of hydrogen on CS-induced <i>muc5ac</i> transcription analyzed by realtime RT-PCR. …”

Effects of age of exercise onset on body composition across the lifespan. by Agnieszka Mika (306138)

TLR4 and NF-κB signaling pathway is required for the reduction of let-7b expression in response to <i>H.pylori</i> infection. by Gui-gen Teng (380044)

“…<p>(A) TKA-242 (1 uM) decreased the expression of TLR4 protein in AGS and GES-1 cells with <i>H.pylori</i>-infection. …”

SOCS3 regulated the fate of HSCs. by Yu-xiao Liu (146872)

“…Bar = 50 μm. (B) BFU-E and CFU-E derived from shSOCS3-1 CD34⁺ cells. …”

Mechanism of SFK phosphorylation and negative regulation of PKA in chicken sperm. by Chathura Priyadarshana (9635328)

“…<p>Sperm were incubated with 0–50 μM H-89 (PKA inhibitor), 25 μM KH7 (sAC inhibitor), 50 μM MDL (tmAC inhibitor), 0–250 μM PTP inhibitor, or EGTA-AM in the presence or absence of SKI606 and SU6656 and then subjected to immunodetection for p-SFK-Y416 or p-PKAs. …”

<i>In vitro</i> fluorescence imaging and physicochemical characterization of the 3WJ-n × Bro fluorescent aptamer. by Sha Liu (80416)

“…T_m represents the temperature at which fluorescence intensity decreases to 50% of the initial value. Error bars represent mean ± SD (n = 5). …”

Gap detection with the AT1 model. by Javier Estrada (243042)

“…<p><b>(A)</b> Plots of cytoplasmic Ca²⁺ for three representative cells in three experiments in which a step increase in histamine was interrupted by two (expt. 21 & 23) or five (expt. 22) gaps, with the size of the gap changing between experiments as shown. …”

Metabolic parameters and beta activity during infusion of human insulin, insulin detemir and saline in 10 overweight individuals. by Otto Tschritter (36354)

“…Blood glucose was measured twice at baseline and every 5–10 minutes during the infusion of human insulin, insulin detemir or saline. …”