Data_Sheet_1_The change of plasma metabolic profile and gut microbiome dysbiosis in patients with rheumatoid arthritis.PDF by Jing Zhu (27724)

“…Objective<p>Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, which is associated with progressive disability, systemic complications, and early death. …”

Image_2_Gonadotropin-Releasing Hormone Receptor-Targeted Near-Infrared Fluorescence Probe for Specific Recognition and Localization of Peritoneal Metastases of Ovarian Cancer.JPEG by Qiyu Liu (3961796)

“…The fluorescence signal of peritoneal metastases peaked in intensity at 2 h and maintained for up to 48 h. ICG also showed a weak signal in the tumor lesions due to the enhanced permeability and retention effect, but the intensity decreased quickly within 48 h.…”

Low Resolution Data-Independent Acquisition in an LTQ-Orbitrap Allows for Simplified and Fully Untargeted Analysis of Histone Modifications by Simone Sidoli (167157)

“…By exploiting an LTQ-Orbitrap mass spectrometer, we parallelized MS and MS/MS scan events using the Orbitrap and the linear ion trap, respectively, decreasing the total scan time. This, in combination with large windows for MS/MS fragmentation (50 <i>m</i>/<i>z</i>) and multiple full scan events within a DIA duty cycle, led to a MS scan cycle speed of ∼45 full MS per minute, improving the definition of extracted LC–MS chromatogram profiles. …”

Image_1_Cardiac Involvement in Human Immunodeficiency Virus Infected Patients: An Observational Cardiac Magnetic Resonance Study.TIFF by Chengxi Yan (9602174)

“…</p><p>Results: HIV-infected patients had lower left (55.3 ± 6.5 vs. 63.0 ± 7.9%, P < 0.001) and right ventricular systolic function (35.9 ± 15.7 vs. 50.8 ± 9.3%, P < 0.001). Radial systolic strain (30.7 ± 9.3 vs. 39.3 ± 9.4%, P = 0.001), circumferential systolic strain (−17.5 ± 2.6 vs. −19.4 ± 2.7%, P = 0.008), and longitudinal systolic strain (−9.4 ± 5.7 vs. −12.8 ± 3.1%, P = 0.012) were also decreased in HIV. …”

<b>The burden of diabetes mortality by county, race, and ethnicity in the USA, 2000–2019</b> by Hasan Nassereldine (14605604)

“…<p dir="ltr">Objective</p><p dir="ltr">Diabetes is a leading cause of death in the USA. Previous studies have found substantial racial and ethnic and geographical disparities in diabetes mortality, however research considering racial and ethnic and geographical disparities simultaneously has been limited. …”

Lhx1 controls the differential expression of Dab1 in LMC neurons. by Elena Palmesino (179868)

“…<p>(A–N) e12.5 lumbar spinal cord Dab1 protein (A–H) and mRNA (I–N) expression in LMCl (Isl1⁻ Foxp1⁺) is decreased in <i>Lhx1^COND</i> mutants (E–H, L–N) compared to control embryos (A–D, I–K). …”

Muscle fiber hypertrophy in response to 6 weeks of high-volume resistance training in trained young men is largely attributed to sarcoplasmic hypertrophy by Cody T. Haun (4183900)

“…The 15 fCSA hypertrophic responders experienced a +23% increase in mean fCSA from PRE to W6 (p<0.001) and, while muscle glycogen concentrations remained unaltered, citrate synthase activity levels decreased by 24% (p<0.001) suggesting mitochondrial volume decreased. …”

Clinical Connections KG version 20240501 by Jennifer Hadlock (20465732)

“…<p dir="ltr">The <a href="https://github.com/NCATSTranslator/Translator-All/wiki/Multiomics-Clinical-Connections-KP" rel="noreferrer" target="_blank">Clinical Connections KG</a> is created and maintained by the <a href="https://github.com/NCATSTranslator/Translator-All/wiki/Multiomics-Provider" target="_blank">Multiomics Provider</a> team from the Institute for Systems Biology in Seattle, WA. …”

Mass spectrometry-based determination of APLP2 α- and β-shedding sites. by Sebastian Hogl (349573)

“…This peptide was analyzed in a mass spectrometer. (<b>B</b>) HEK293 cells were transiently transfected with the APLP2TF construct and either treated with TAPI-1 (50 µM) or DMSO as a solvent control. …”

Increasing branch occupancy with inhibitory synapses enhances Inhibitory Level at the junction but saturates relative inhibitory accumulation. by Christopher Brian Currin (7064300)

“…<p><b>(A)</b> The percentage of dendritic branches which have inhibitory synapses, “effective number of synapses”, indicates the diminishing return in additional IL when adding more synapses. …”

Effect of inhibitors of caveolae- and clathrin-dependent endocytosis on TGFBIp internalization. by Seung-il Choi (50895)

“…<p><b>A</b>. Inhibitors of endocytosis decreased TGFBIp levels in corneal fibroblasts. …”

Xenobiotic response regulatory factors are specific to one or more cytoprotective pathways. by David E. Shore (123998)

“…Representative images of conditions with decreased cytoprotective gene expression are outlined in red, and the fold reduction in GFP expression, quantified in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002792#pgen-1002792-t001" target="_blank">Table 1</a>, is shown in the lower right. …”

DataSheet_1_Impacts of coral bleaching on reef fish abundance, biomass and assemblage structure at remote Aldabra Atoll, Seychelles: insights from two survey methods.zip by Anna Koester (11805572)

“…In contrast, extended fish surveys in 2015 and 2020 showed a 55–60% reduction in overall abundance on shallow and deep reefs, and a 69% reduction in biomass on shallow reefs, with decreases in biomass occurring in all functional groups. …”

Table_2_Associations between repetitive head impact exposure and midlife mental health wellbeing in former amateur athletes.docx by Claire V. Buddenbaum (18622372)

“…While not statistically significant, the contact group showed increased depressive [2.37 (0.05, 4.79), p=0.07] and ADHD symptoms [4.53 (0.51, 9.57), p=0.08] compared to controls. In a secondary analysis, a distinct trend emerged within the contact group, revealing pronounced elevations in mental health symptoms among individuals with lower socioeconomic status (<$50,000/year) compared to higher income subgroups, and these symptoms decreased as income levels rose [depression: -3.08 (-4.47, -1.7), p<0.001; anxiety: -1.95 (-3.15, -0.76), p=0.002; ADHD: -4.99 (-8.28, -1.69), p=0.004; PTSD: -4.42 (-7.28, -1.57), p=0.003; aggression: -6.19 (-11.02, -1.36), p=0.01]. …”

Low doses of IL-4 and IL-13 enhance cellular proliferation. by Quentin D’Arcy (13919516)

“…<p><b>A, B.</b> N1 and SFT1 prostate fibroblasts and HLF primary lung fibroblasts were cultured in serum-free defined media supplemented with vehicle or increasing doses (1–100 ng) of human recombinant IL-4 (<b>A</b>) or IL-13 (<b>B</b>) for 24 hours. …”

<i>cic</i> inactivation promotes ISC proliferation and hyper-activation inhibits ISC proliferation. by Yinhua Jin (838896)

“…Scale bars represent 20 μm in A-B and 50 μm in E-G.</p>…”

Table_1_Anaplasma phagocytophilum Activates NF-κB Signaling via Redundant Pathways.XLSX by J. Stephen Dumler (7274654)

“…Among A. phagocytophilum-infected HL-60 cells, nuclear NF-κB p50, p65, and p52 were detected by immunoblots or iTRAQ proteomics. …”

Image_1_Epidemiological and Clinical Characteristics of Five Rare Pathological Subtypes of Hepatocellular Carcinoma.pdf by Xiaoyuan Chen (322516)

“…</p>Results<p>Despite scirrhous carcinoma, which showed a decreasing trend (APC = -6.8%, P = 0.025), the morbidity of other rare subtypes remained stable from 2004 to 2018. …”

Image_1_Associations between repetitive head impact exposure and midlife mental health wellbeing in former amateur athletes.tiff by Claire V. Buddenbaum (18622372)

“…While not statistically significant, the contact group showed increased depressive [2.37 (0.05, 4.79), p=0.07] and ADHD symptoms [4.53 (0.51, 9.57), p=0.08] compared to controls. In a secondary analysis, a distinct trend emerged within the contact group, revealing pronounced elevations in mental health symptoms among individuals with lower socioeconomic status (<$50,000/year) compared to higher income subgroups, and these symptoms decreased as income levels rose [depression: -3.08 (-4.47, -1.7), p<0.001; anxiety: -1.95 (-3.15, -0.76), p=0.002; ADHD: -4.99 (-8.28, -1.69), p=0.004; PTSD: -4.42 (-7.28, -1.57), p=0.003; aggression: -6.19 (-11.02, -1.36), p=0.01]. …”

Data_Sheet_1_Total yeast and mold levels in high THC-containing cannabis (Cannabis sativa L.) inflorescences are influenced by genotype, environment, and pre-and post-harvest handl... by Zamir K. Punja (9025130)

“…The variables which significantly (p < 0.05) decreased TYM in samples were: genotypes with lower numbers of inflorescence leaves, air circulation achieved by fans during inflorescence maturation, harvesting during November–April, hang-drying of entire inflorescence stems, and drying to a moisture content of 12–14% (water activity of 0.65–0.7) or lower which was inversely correlated with cfu levels. …”