Models spontaneously develop separate modules for ‘vector-‘ and ‘transition’-based strategies. by Denis C. L. Lan (21807775)

“…Lesioning ‘vector’ units leads to a decrease in use of ‘direction’ actions and lesioning ‘transition’ units leads to a decrease in use of ‘state’ actions. …”

Novel Nuclear Factor-KappaB Targeting Peptide Suppresses β-Amyloid Induced Inflammatory and Apoptotic Responses in Neuronal Cells - Fig 6 by Mythily Srinivasan (3233949)

“…<p>Effect of GILZ analog (GA) treatment on human fetal brain cells (HFB): (A,B): Select GA decrease metabolic activity in Aβ_1–42 exposed HFB. …”

Video1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.AVI by Jose M. Ferrero (6705797)

“…Our results indicate that the primary rising phase of [K+]o is mainly due to the imbalance between K⁺ efflux, that increases slightly, and K⁺ influx, that follows a reduction of the NaK pump activity by more than 50%. …”

Seizure changes during study phases. by Mark Bodner (33604)

“…It can be seen from the graphs that while both groups of subjects exhibited a significant reduction in seizures, that subjects with idiopathic seizures exhibited a greater decrease in both treatment and follow-up years than those with symptomatic seizures.…”

WIKI4 inhibits the functional outcomes of Wnt/ß-catenin signaling. by Richard G. James (114424)

“…In <b>B-F</b>, LCM = control L cell CM, WNT3A = Wnt3a CM; both 50% (vol/vol) in KSR medium.…”

DataSheet1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.docx by Jose M. Ferrero (6705797)

“…Our results indicate that the primary rising phase of [K+]o is mainly due to the imbalance between K⁺ efflux, that increases slightly, and K⁺ influx, that follows a reduction of the NaK pump activity by more than 50%. …”

The distribution of Tbr2+ mitoses shifts to the outer subventricular zone (oSVZ) during early stages of cortical development in macaque, but not in ferret or rat. by Verónica Martínez-Cerdeño (155789)

“…There was a steady decrease in the proportion of Tbr2+ divisions occurring in the iSVZ. …”

The Antihelmintic Drug Pyrvinium Pamoate Targets Aggressive Breast Cancer by Wei Xu (28953)

“…A decrease in activity of the TIC surrogate aldehyde dehydrogenase was observed in PP-treated cells, and inhibition of WNT signaling by PP was associated with down-regulation of a panel of markers associated with epithelial-mesenchymal transition. …”

The Cost-Effectiveness of Intermittent Preventive Treatment for Malaria in Infants in Sub-Saharan Africa by Lesong Conteh (231114)

Neonatal Intensive Care in a Karen Refugee Camp: A 4 Year Descriptive Study by Claudia Turner (160713)

“…Early prematurity (<34 weeks) carried the highest risk of mortality (OR 9.5, 95% CI 5.4–16.5, p<0.001). There was a significant decrease in mortality from 19.3% (2008) to 4.8% (2011) among the infants admitted for prematurity (p=0.03). …”

Data_Sheet_1_Short-Chain and Unsaturated Fatty Acids Increase Sequentially From the Lag Phase During Cold Growth of Bacillus cereus.ZIP by Marina Français (11169621)

“…In a second step, an increase in Δ^5,10 di-saturated fatty acids and in monounsaturated fatty acids in Δ⁵ position, at the expense of unsaturation in Δ¹⁰, started during exponential phase and continued until the end of stationary phase, suggesting a role in growth consolidation and survival at cold temperatures. …”

Automation of lettuce seedlings irrigation with sensors deployed in the substrate or at the atmosphere by Ana Carolina Mendes Bezerra (6072065)

“…All biometric and physiological traits evaluated decreased as the SIC tensions increased. Thus, tensions of 4.0 (substrate sensor) and 3.5 kPa (atmospheric sensor) showed greater potential for producing vigorous seedlings, with WUE average values of 1.86 and 1.37 g L−1, respectively. …”

Down-Regulation of Canonical and Up-Regulation of Non-Canonical Wnt Signalling in the Carcinogenic Process of Squamous Cell Lung Carcinoma by Domokos Bartis (364771)

“…Our studies identified Wnt11 and Wnt5a as regulators of cadherin expression and potentiated relocation of β-catenin to the nucleus as an important step in decreased cellular adhesion. …”

Fig 1 - by M. Latorre (8840546)

“…<p>Fully developed, mechanobiologically equilibrated, axisymmetric dilatations of an initially cylindrical aortic segment caused by a mild (first column) or severe (second column) localized (via the respective parameter <i>ϑ</i>_{<i>central</i>} in Eq (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008273#pcbi.1008273.e024" target="_blank">9</a>)) loss of elastic fiber integrity (first row, parameter <i>c</i>^<i>e</i>, mild 32% and severe 62% reduction), decrease in collagen cross-linking (second row, parameter , mild 9%, severe 23% reduction), loss of smooth muscle contractility (third row, parameter <i>T</i>_<i>max</i>, mild 60%, severe 100% reduction), compromised mechanosensing (fourth row, parameter <i>δ</i>, mild 7.5%, severe 18.5%, absolute), or compromised mechanoregulation (fifth row, parameter <i>G</i>^<i>c</i>, mild 0.4%, severe 1.2%, relative change), with the risk factors of hypertension (third column, 50% increase in blood pressure) and aortic aging (fourth column, uniform 30% loss of elastic fiber integrity) superimposed on the mild insults. …”

<i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality... by Ashwani Kumar (55732)

“…The mechanistic interpretation of developed models explains the role of different structural attributes in predicting the pIC₅₀ of pyrazole sulfonamides extracted from the crystal structure of Leishmania major N-myristoyltransferase (NMT) along with co-crystallized myristoyl-CoA and ligands NMT106, NMT157, NMT187 and NMT236 (PDB ID: 4A2Z, 4A30, 4A32, 2WSA). …”

The Protein <i>O</i>-glucosyltransferase Rumi Modifies Eyes Shut to Promote Rhabdomere Separation in <i>Drosophila</i> by Amanda R. Haltom (664189)

“…The intracellular accumulation of Eys and the IRS defect worsen in <i>rumi</i> mutants raised at a higher temperature, and are accompanied by a ∼50% decrease in the total level of Eys. …”

Table_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.docx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

DataSheet_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.xlsx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

Estrogen Receptor inhibition prevents estradiol-17ß-d-glucuronide (E17G)-induced endocytic internalization of Abcb11 and Abcc2 in perfused rat liver. by Ismael R. Barosso (116985)

“…Distribution profiles of livers treated with E17G+ICI was similar to control and indicated a significantly decreased of Abcb11 and Abcc2 internalization (P<0.01 versus E17G). …”

Data_Sheet_1_Antimicrobial Resistance and Livestock Trade for Low and Middle Income Countries: Regional Analysis of Global Coordination Policies.pdf by Charalampos Avraam (10361288)

“…We found that a user fee that increases the price of antimicrobials by 50% globally leads to a 33% reduction in global antimicrobial use. …”