Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study by Klaus G. Parhofer (12280424)

“…A total of 33.1% achieved the LDL-C goal (<55 mg/dL) according to EAS/ESC dyslipidaemia guidelines, with achievement rates ranging from 16.3% in those without PCSK9-mAb and statins to 50.5% in those on combined PCSK9-mAb, statins, and/or ezetimibe. …”

Table2_Longitudinal evaluation of manufacturer-specific differences for high-sensitive CRP EQA results.XLSX by Nathalie Weiss (17877374)

“…Furthermore, assays are currently traceable to different international standard preparations, which might have a negative impact on future harmonization.</p>…”

Basic information of the participants. by Jincheng Huang (9306806)

“…</p><p>Methods</p><p>This study was a multi-center prospective observational study. …”

Data Sheet 1_Cross-cultural adaptation and validation of the Spanish version of the Prevent for Work questionnaire.csv by Julia Blasco-Abadía (18774070)

“…</p>Methods<p>The first phase consisted of a forward-and-backward translation process and evaluating the face-validity of the questionnaire among 30 Spanish workers. …”

Silica Nanoparticles Synthesized from 3,3,3-Propyl(trifluoro)trimethoxysilane or <i>n</i>‑Propyltrimethoxysilane for Creating Superhydrophobic Surfaces by Abul Bashar Mohammad Giasuddin (6395144)

“…The 3F and <i>n</i>PM precursor silanes were solubilized by acid hydrolysis followed by base condensation to synthesize NPs ranging from 50 to 300 nm, dependent on silane concentration. …”

Autophagy Is Involved in the Cardioprotection Effect of Remote Limb Ischemic Postconditioning on Myocardial Ischemia/Reperfusion Injury in Normal Mice, but Not Diabetic Mice by Zhihua Han (28856)

“…To analyze the role of autophagy, western blot and immunohistochemistry was performed. Our data showed that a decreased sequestosome 1 (SQSTM1/p62) level, an increased Beclin-1 level, and higher ratio of LC3-II/LC3-I were observed in ND RIPostC group, but not DM RIPostC group.…”

Biogeochemical Importance of the Bacterial Community in Uranium Waste Deposited at Key Lake, Northern Saskatchewan by Viorica F. Bondici (2831075)

“…To determine the potential for biologically mediated decreases in redox potential and ferrihydrite reduction, a series of microcosm assays were performed. …”

FGF9 overexpression in Type I PPB phenocopies ectopically expressed FGF9 in mouse lung epithelium. by Yongjun Yin (740151)

“…Scale bars: A and B, 20 μm; C-P, 50 μm. Sample numbers (n) are indicated on the data bars.…”

Silica Nanoparticles Synthesized from 3,3,3-Propyl(trifluoro)trimethoxysilane or <i>n</i>‑Propyltrimethoxysilane for Creating Superhydrophobic Surfaces by Abul Bashar Mohammad Giasuddin (6395144)

“…The 3F and <i>n</i>PM precursor silanes were solubilized by acid hydrolysis followed by base condensation to synthesize NPs ranging from 50 to 300 nm, dependent on silane concentration. …”

Antiviral activity of shikonin ester derivative PMM-034 against enterovirus 71 in vitro by Y. Zhang (67313)

“…This study aimed to examine the antiviral activity of PMM-034, a shikonin ester derivative, against EV71 in rhabdomyosarcoma (RD) cells. …”

Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo‑<i>p</i>‑dioxin by Rance Nault (3847747)

“…Phosphatidylserines, phosphatidylethanolamines, phosphatidic acids, and cardiolipins decreased 4.1-, 5.0-, 5.4- and 7.4-fold, respectively, while ceramides increased 6.6-fold. …”

Tradeoffs in resistance to two antibiotics. by Ellsworth M. Campbell (313943)

“…With the highest tradeoff constraint and <i>ω</i> = 1, <i>MICA</i>₃ and <i>MICB</i>₃ equal zero and are same as the <i>MICA_S</i> and <i>MICB_S</i> values for sensitive <i>S</i> bacteria (○). As <i>ω</i> is decreased from 1.0, 0.75, 0.50, 0.25 to 0, the progression (→) represents the double-resistant <i>R</i>₃ experiencing less and less tradeoff. …”

Genotoxic Mechanisms of Erythrophleum suaveolens Stem Bark Extracts and Fractions in MCF-7 Breast Cancer Cells via Mitochondrial and Non-Mitochondrial Pathways by Lateef Sulaimon (21706283)

“…After 72 hours, ESSB-treated MCF-7 cells showed a significant (p < 0.05) increase in DNA fragmentation and comet tail DNA percentages (flavonoids induced a 1.21-fold increase in comet tail length). …”

DataSheet1_CYP2D6 gene polymorphism and apatinib affect the metabolic profile of fluvoxamine.docx by Zhize Ye (13583515)

“…Meanwhile, the produce of desmethyl fluvoxamine was dramatically inhibited, both AUC and C_max decreased significantly. Mechanistically, apatinib inhibit the generation of fluvoxamine metabolite with a mixed manner both in RLM and HLM. …”

Data_Sheet_1_Selenium Effect Threshold for Soil Nematodes Under Rice Biofortification.xlsx by Jiaping Song (317369)

“…In this study, a rice pot experiment was carried out to test how selenite supply (untreated control (0), 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 100, or 200 mg Se kg⁻¹) in soil affected rice growth, rice Se accumulation, and soil nematode abundance and composition. …”

Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo‑<i>p</i>‑dioxin by Rance Nault (3847747)

“…Phosphatidylserines, phosphatidylethanolamines, phosphatidic acids, and cardiolipins decreased 4.1-, 5.0-, 5.4- and 7.4-fold, respectively, while ceramides increased 6.6-fold. …”

Clock function in EO neurons is not required for synchronization to temperature cycles in constant darkness. by Clara Lorber (14106749)

“…C) Percentage of flies decreasing their locomotion with a slope steeper (blue), or lower (orange) than 50% of the theoretical slope after the morning peak at DD2 following DDTC. …”

Table 1_Screening and identification of the H1R antagonists from natural products by BODIPY FL histamine recognition and DPHD-anchored bombardment coupled with target cell extracti... by Xinqi Li (14029494)

“…The BODIPY FL histamine recognition results revealed the significant blocking effects on H1R binding by pseudoephedrine (50 μM) and dictamnine (100 μM). Pseudoephedrine (200 μM) and dictamnine (100 μM) markedly decreased the histamine-induced increase in intracellular calcium ion (Ca²⁺) concentration. …”

Table 1_Mechanism of action of Butein in cutaneous squamous cell carcinoma through regulation of the TWEAK-FN14 signaling pathway.docx by Qinyi Dong (22824800)

“…</p>Results<p>Molecular docking predicted that Butein exhibits strong binding affinity with TWEAK, FN14, cIAP1, and TRAF1/2 proteins, with binding energies ranging from −5.8 to −6.9 kcal/mol.In vitro experiments demonstrated that Butein inhibited the proliferation and migration of human cSCC cell line A431 with an IC₅₀ of 43 μM and induced dose-dependent apoptosis. …”

Effect of nitrogen levels and nitrogen ratios on lodging resistance and yield potential of winter wheat (<i>Triticum aestivum</i> L.) by Mingwei Zhang (661218)

“…A field experiment with Yangmai 20 as research material (a widely-used variety) was conducted to study the effects of different nitrogen levels and ratios on culm morphological, anatomical characters and chemical components and to explore the nitrogen application techniques for lodging tolerance and high yield. …”