Table 3_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.xlsx by Hongyu Zhou (352858)

“…Introduction<p>Age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, with limited effective treatments available. …”

Proliferation and demyelination in the early stages after crush injury. by Anna Henzi (9635793)

“…Scale bar: 50 μM. (b) Ki67-proliferation index (% ki67-positive nuclei) as quantified from IF images was highest at 5 d.p.c. and decreased at later stages post crush injury. …”

Study design. by Eun Sol Kang (18309844)

“…The study population comprised patients with at least one record of a principal diagnosis of breast cancer (ICD-10 code: C50) from the national health insurance claim database between 2010 and 2019. …”

Data Sheet 4_Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.xlsx by Nana Wang (533812)

“…The expressions of TCF3, E2F1, E2F3, and LRFN4 were correlated with the IC50 of multiple drugs.</p>Conclusion<p>LRFN4 may serve as a novel prognostic biomarker for LUAD, shows specific overexpression in LUAD and may be a potential therapeutic target for LUAD patients.…”

Data Sheet 2_Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.xlsx by Nana Wang (533812)

“…The expressions of TCF3, E2F1, E2F3, and LRFN4 were correlated with the IC50 of multiple drugs.</p>Conclusion<p>LRFN4 may serve as a novel prognostic biomarker for LUAD, shows specific overexpression in LUAD and may be a potential therapeutic target for LUAD patients.…”

DataSheet2_Safflower Polysaccharide Inhibits AOM/DSS-Induced Mice Colorectal Cancer Through the Regulation of Macrophage Polarization.doc by Qun Wang (102815)

“…Taken together, all results suggested that SPS-1 could be a therapeutic option for the prevention and treatment of CRC.…”

Serotonin and dopamine prevent hypotherma/rewarming cell death via increased H₂S production through upregulation and allosteric activation of cystathionine-β-synthase (C... by Fatemeh Talaei (189998)

“…<p>(<b>A</b> and <b>B</b>) Immunostaining demonstrating the expression of CBS in DDT-1 (A) and SMAC (B). …”

Effect of CSE Gene Deletion on Liver and Lung MPO Activity and Organ Injury in Mice Following CLP Induced Sepsis. by Ravinder Reddy Gaddam (2939934)

“…<p>(A) Liver MPO activity and (B) Lung MPO activity. …”

Treatment with TrkB agonists reduces food intake and weight in mice. by John C. Lin (43821)

“…<p>a, Daily IV injection of 0.6, 2 or 4 mg/kg of NT4 (n = 6 per group) resulted in dose dependent reduction in average daily food intake over 5 days in adult male DIO mice (One way ANOVA, P = 0.0098, F = 4.967 with Dunnett's posttest, P<0.01 for 4 mg/kg group compared to the vehicle group, while no statistically significant effects were observed at 0.6 or 2 mg/kg). b, Daily IV injection of 0.6, 2 or 4 mg/kg of NT4 (n = 6 per group) resulted in dose dependent reduction in body weight in adult male DIO mice (Two way ANOVA, P<0.0001 with Bonferroni's posttests, data are presented as % change relative to baseline body weight). c, Weekly IV injection of 2 mg/kg BDNF (n = 7) or NT4 (n = 7) led to significant weight loss compared to the vehicle treatment (n = 8) in adult male DIO mice at 10 days after the first dose (One way ANOVA, P = 0.002, F = 9.08 with Dunnett's posttest). d, Single IV injection of 3 mg/kg TrkB agonist monoclonal antibody (n = 7) significantly reduced body weight relative to control IgG treatment (n = 7) in adult male DIO mice 10 days after dosing (Student's t test, 2 tailed, P = 0.04). e–f, Daily treatment of Leptin receptor-deficient, 12 week old female <i>db/db</i> mice for 30 days with IV-delivered 20 mg/kg of NT4 (n = 7) decreased daily food intake by 50–80% (e), and body weight by 40% (f) relative to the vehicle treated mice (n = 8).…”

Exercise-Induced Splanchnic Hypoperfusion Results in Gut Dysfunction in Healthy Men by Kim van Wijck (212826)

“…Splanchnic perfusion rapidly decreased during exercise, reflected by increased gap_g-apCO₂ from −0.85±0.15 to 0.85±0.42 kPa (p<0.001). …”

Table_1_High clinical diagnostic accuracy of combined salivary gland and myocardial metaiodobenzylguanidine scintigraphy in the diagnosis of Parkinson’s disease.DOCX by Shuangfang Li (13202799)

“…</p>Results<p>The combination of left parotid and left submandibular gland early images had a good performance in distinguishing PD from NPD, with sensitivity, specificity, and accuracy of 50.00, 94.74, and 72.37%, respectively. …”

Differences in H3K4Me3 enrichment between WT and <i>Mist1^−/−</i> pancreatic tissue are targeted. by Rashid Mehmood (336455)

“…(<b>B, C</b>) Schematic representation of ChIP-seq data showing H3K4Me3 enrichment for genes previously published with (<b>B</b>) decreased expression (<i>Cdkn1a</i>, <i>Rab26</i>) or (<b>C</b>) increased expression (<i>Cckar</i>) in <i>Mist1^−/−</i> (M1-) pancreatic tissue. …”

<i>M</i>. <i>bovis</i> encodes an anti-apoptotic protein GcvH. by Qiao Pan (18611470)

“…<p>(A) The group-D MAPs decreased cleaved Caspase-3 levels by Western blotting analysis. …”

Image 1_Application and validation of the machine learning-based multimodal radiomics model for preoperative prediction of lateral lymph node metastasis in papillary thyroid carcin... by Jia-Wei Feng (10754067)

“…A total of 874 ultrasound radiomics features and 1433 CT radiomics features were extracted and selected using LASSO regression. …”

Ser1179D mutation enhanced both eNOS and reductase domain O₂^.- generation capacity. by Hu Peng (396074)

“…Data shown are means from three experiments. (A) Wild type eNOS produced a strong DEPMPO-OOH adduct signal in the Tris HCl buffer in the presence of 0.5 mM Ca²⁺, 10 μg/ml CaM (left up-trace). …”

MEK kinase positively and transcriptionally controls CD70 membrane and global expression. by Christine Pich (367328)

“…<p>LB1319-MEL and WM-266-4 cells were treated with 5 μM of U0126 for 72 h then analyzed by Western Blot for CD70, phospho-MEK and MEK expression. Actin was used as a loading control <b>(A)</b>. LB39-MEL CD70+ cells were treated with 5 μM of U0126 for 72 h then fixed and processed for immunofluorescence directed against CD70. …”

<i>In-vitro</i> antioxidant and <i>in-vivo</i> anti-aging with stress resistance on <i>Caenorhabditis elegans</i> of herbaceous peony stamen tea by Jiasong Meng (775090)

“…Moreover, PLS extracted at the same concentrations had no toxic effects on <i>C. elegans</i>, and the treatment with 1.2 mg·mL⁻¹ PLS extract significantly extended <i>C. elegans</i> lifespan that was not at the expense of reducing its reproduction and <i>Escherichia coli</i> OP50 growth. Furthermore, the same treatment extract enhanced their locomotion behavior and decreased their intestinal autofluorescence during the aging process. …”

DataSheet_1_The Application Value of Metagenomic and Whole-Genome Capture Next-Generation Sequencing in the Diagnosis and Epidemiological Analysis of Psittacosis.zip by Zhimei Duan (10656014)

“…</p>Results<p>mNGS successfully detected the pathogen in all 16 cases (100%), while qPCR was positive only in 5 out of 10 cases (50%), indicating a significantly higher sensitivity of mNGS than qPCR (p < 0.01). …”

Data Sheet 3_Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.xlsx by Nana Wang (533812)

“…The expressions of TCF3, E2F1, E2F3, and LRFN4 were correlated with the IC50 of multiple drugs.</p>Conclusion<p>LRFN4 may serve as a novel prognostic biomarker for LUAD, shows specific overexpression in LUAD and may be a potential therapeutic target for LUAD patients.…”

Data Sheet 1_Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma.xlsx by Nana Wang (533812)

“…The expressions of TCF3, E2F1, E2F3, and LRFN4 were correlated with the IC50 of multiple drugs.</p>Conclusion<p>LRFN4 may serve as a novel prognostic biomarker for LUAD, shows specific overexpression in LUAD and may be a potential therapeutic target for LUAD patients.…”