M002 treatment of malignant rhabdoid kidney tumor xenografts. by Michael L. Megison (469463)

“…In the M002 treated G401 xenografts, there was a significant decrease in tumor growth that began at day 7 following treatment that continued to the end of the study. …”

table_1_The Severe Deficiency of the Somatotrope GH-Releasing Hormone/Growth Hormone/Insulin-Like Growth Factor 1 Axis of Ghrh−/− Mice Is Associated With an Important Splenic Atrop... by Gwennaelle Bodart (5343917)

Image texture parameter “granularity” for analysis of early mHTT aggregation. by Nikisha Carty (395638)

Transgenerational phenotypes. by Michael J. Carvan III (591743)

Functional <i>in vitro</i> study on hsa-miR-9*. by Anna Onnis (361465)

“…The level of hsa-mir-9* increased in a dose-dependent manner. <b>(B) Relative expression by qRT-PCR of hsa-mir-9* in LCL transfected with an hsa-miR-9* inhibitor</b>, at the concentration of 50 nM, compared to non-treated LCL and LCL trasfected with a negative control (I NC). …”

Effects of the activation and inhibition of NOTCH signalling on spinal cord progenitor cell proliferation and neuronal generation. by Barbara Hämmerle (36261)

“…<p>A–A′. Confocal projection over 50 µm at the level of the 12^th and 13^th somites of an HH13 embryo that was electroporated with NICD at stage HH10. …”

The Gc fusion loops. by Pablo Guardado-Calvo (2325709)

“…VLPs were incubated with liposomes labeled with a fluorescent dye (DPH, see <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005813#sec013" target="_blank">Materials and Methods</a>) at pH 7.4 or 5.5. Fractions of the step gradient sedimentation were examined for the presence of Gc by western blot and liposomes by fluorescence. …”

mast cell quantification raw data.xlsx by Soumya Gupta (14513114)

“…</p> <p><br></p> <p>1.jpg : apalstic anemia, magnification 4X, hematoxylin and eosin staining</p> <p>2.jpg: metachromatically stained mast cells, magnification 10X, Toluidine Blue staining</p> <p>3.jpg: metachromatically stained mast cells, magnification 20X, Toluidine Blue staining</p> <p>4.jpg: metachromatically stained mast cells, magnification 40X, Toluidine Blue staining</p> <p>5.jpg : MDS-h, hypoplastic marrow, magnification 4X, hematoxylin and eosin staining</p> <p>6.jpg: metachromatically stained mast cells, magnification 40X, Toluidine Blue staining</p> <p><br></p> <p>File: procedure of CD34 IHC staining</p> <p>this file provides the step by step procedure for CD34 IHC satining including te reagents used and time frames.…”

Supplementary files by Ali nasith (20645786)

“…Forest plot was made using Review manager v5.4 with Odds ratio as measure effect. The inclusion study characteristics and findings from each study were summarised in an extraction table and then synthesised qualitatively. …”

Quantitative PCR validation of mitochondrial genes. by Kwang H. Choi (121395)

“…<p>A scatter plot with a line of best fit demonstrates that each gene in the PFC shows either increase or decrease in expression across age (qv <0.05). …”

Inhibitors of 5-LOX block TRPM7-mediated cell rounding. by Hsiang-Chin Chen (247146)

“…An asterisk indicates treatments that produced a decrease in cell rounding that was significantly different from 293-TRPM7 cells grown in tetracycline.…”

MCCD ventilation - Case-Figure 7 by Stefan Schaller (4976000)

“…The drop in the ventilation rate between 18:50 and 19:10 minutes was due to a leak in the airway circuit. …”

Sensitivity Analysis of Increasing Baseline Effectiveness of Self-Administered Antiretroviral Therapy. by Caitlin J. McCabe (365598)

“…As the proportion of women who have a full response to self-administered HAART increases, there is a decrease in the proportion of women for whom DOT is cost-effective. …”

Sensitivity analysis. by Billy J. Gardner (10988034)

“…<p>The plot shows how much R_t changes from a 10% increase (red) or 10% decrease (blue) in that model parameter relative to values in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009122#pcbi.1009122.t001" target="_blank">Table 1</a> (with τ_Is = 0.2 and κ = 1). …”

Total fluorescence of Z-RR-AMC and Z-FR-AMC cleavage by planaria lysate is reduced by inhibition of cathepsin activity. by Louise S. Goupil (2922159)

“…<p><b>(A)</b> Whole worm lysate was pre-incubated with 50μM E-64, a pan-cysteine protease inhibitor, before assaying with the fluorescent probe Z-RR-AMC. …”

Regulation of nestin expression by thrombin and cell density in cultures of bone mesenchymal stem cells and radial glial cells-3 by Franz Wautier (86113)

“…Protein extracts were separated and revealed with anti-nestin and anti-actin antibodies. A decrease of nestin expression is apparent from an initial density of 50·10cells/cm(G). …”

Real-Time Cytotoxicity Assay for Rapid and Sensitive Detection of Ricin from Complex Matrices by Diana Pauly (170378)

“…Upon incubation with toxin the cell status and the cytotoxic effect were visualized using a characteristic cell index–time profile. For ricin, tested in concentrations of 0.06 ng/mL or above, a concentration-dependent decrease of cell index correlating with cytotoxicity was recorded between 3.5 h and 60 h. …”

Data_Sheet_3_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…Two 6-h polysomnographic recordings were performed on two consecutive days on eight full-term lambs: the first after an IV saline injection (control condition, CTRL); the second, after an IV injection of 2.5 μg/kg Escherichia coli LPS 0127:B8 (LPS condition). …”

Data_Sheet_1_The timelines for the price and reimbursement authorization in Italy 2018–2020.pdf by Valentina Gallo (95843)

“…In 2020, the overall process duration for Off-patent pharmaceuticals procedures was equal to 129.8 average days [95% CI: (122.3–137.2)], with a median value of 108.0, whereas for In-patent pharmaceuticals procedures, it was equal to 283.1 average days [95% CI: (267.8–298.5)], with a median value of 284.0. Over time, the trend of the entire duration of the P&R process tended to decrease. …”

An <em>IL28B</em> Genotype-Based Clinical Prediction Model for Treatment of Chronic Hepatitis C by Thomas R. O'Brien (214533)

“…Subjects were re-treated with pegylated-interferon/ribavirin during trial lead-in. We used step-wise logistic regression to calculate adjusted odds ratios (aOR) and create the predictive model. …”