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Table1_IgE and IgG4 epitopes of the peanut allergens shift following oral immunotherapy.xlsx
Published 2023“…While PTAH does not seem to alter the actual peptide binding patterns significantly after one year of treatment, the IgE and IgG4 binding ratios and intensity are altered.</p>Conclusion<p>At a population level, the linear IgE and IgG4 epitopes of 10 peanut allergens overlap and that increase in IgG4 with OIT results in displacement of IgE binding to both conformational and linear epitopes. …”
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Table2_IgE and IgG4 epitopes of the peanut allergens shift following oral immunotherapy.xlsx
Published 2023“…While PTAH does not seem to alter the actual peptide binding patterns significantly after one year of treatment, the IgE and IgG4 binding ratios and intensity are altered.</p>Conclusion<p>At a population level, the linear IgE and IgG4 epitopes of 10 peanut allergens overlap and that increase in IgG4 with OIT results in displacement of IgE binding to both conformational and linear epitopes. …”