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66441
Table_1_Greenhouse Gas Emissions and Health in the Countries of the European Union.docx
Published 2021“…The revealed positive link between CO<sub>2</sub> and DALYs indicated that a decrease in CO<sub>2</sub> may be associated with a decrease in DALYs, but it is also true that this cannot be done without reducing emissions of other combustion products. …”
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66442
Prolonged Ethanol Exposure Increases Nucleoside Uptake Activity of ENT1-216Thr Compared to ENT1-216Ile.
Published 2011“…The substitution of 216Ile to 216Thr showed decreased hydrophobicity by 5.2 using Kyte-Doolittle scale (4.5 vs. −0.7) and increased hydrophilicity by 1.4 using Hopp-Woods scale (−1.8 vs. −0.4). …”
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66443
TRPM8 acting as comparator of temperature.
Published 2013“…When temperature (<i>T</i>) was decreased slowly from 38 to 10°C (B), activities (output, <i>y</i>) of TRPM8 appeared at threshold temperature (28.4±0.5°C, mean ± SEM; n = 5) and increased with a fall in temperature. …”
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66444
Table 1_Biochar of hazelnut shell mitigates cadmium toxicity in forage soybean.xlsx
Published 2025“…Biochar and Cd were applied to mixtures consisting of soil (loamy), sand, and peat (3:1:1, v:v:v). Growth parameters, mineral content, antioxidant enzyme activities (catalase-CAT, peroxidase-POD and superoxide dismutase-SOD), and stress indicators (hydrogen peroxide H<sub>2</sub>O<sub>2</sub>, malondialdehyde-MDA, proline and sucrose) were analyzed. …”
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66445
Time-course of mRNA expression of IGF-system genes and the activation levels of signalling mediators in the E18.8 cochlea.
Published 2010“…<p>(<b>A–D</b>) mRNA expression levels of <i>Igf1</i>, <i>Igf1r</i>, <i>Igfbp2</i> and <i>Igfbp3</i> were analyzed by qRT-PCR in <i>Igf1<sup>+/+</sup></i> (open circles) and <i>Igf1<sup>−/−</sup></i> (closed circles) mice at E15.5 and E18.5 (n = 8), P5, P15, P30, P60 and P90 (n = 6). …”
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66446
CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells.
Published 2025“…<i>n</i> > 600 cells for control and >400 cells for CCDC66 depletion. The mean cilia length in CCDC66-depleted cells decreased to 0.67-fold compared to the mean control length. …”
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66447
Abl kinases are activated in Met-driven mouse mammary tumors and inhibition of Abl kinases suppresses HGF-induced migration and invasion of breast cancer cells.
Published 2015“…***P<0.001; **P<0.01; *P<0.05. Error bars represent mean (n = 3) ± S.E.M. (D-E) HGF-induced breast cancer cell invasion was decreased by Abl kinase inhibitors. …”
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66448
Supplementary Material for: The Cost of Persistent Asthma in Europe: An International Population-Based Study in Adults
Published 2012“…<b><i>Results:</i></b> The mean total cost per patient was EUR 1,583 and was largely driven by indirect costs (i.e. lost working days and days with limited, not work-related activities 62.5%). …”
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66449
Visualization of pathways, interacting network, and validation of selected downstream regulators.
Published 2012“…For CrkL, apoptin induced inhibition of Bcr-Abl phosphorylation lead to the down-regulation of CrkL resulting in lower phosphorytion indicating that apoptin decreases the activation of CrkL, a down-stream substrate of Bcr-Abl. …”
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66450
Observed water repellency in undecomposed and decomposed leaf litter.
Published 2016“…Plant litter species are ranked by decreasing difference between undecomposed and decomposed materials (significantly highest means within each plant litter species: *, <i>P</i> < 0.05, Tukey's HSD post-hoc test from the GLMM in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152565#pone.0152565.s003" target="_blank">S2 Table</a>).…”
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66451
SKF96365 and 2-APB inhibit Src activation.
Published 2015“…<p>Representative immunoblots showing that SKF96365 (A) and 2-APB (B) decreased HMGB1-induced Src phosphorylation. …”
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66452
FHL2 silencing reduces lung metastasis in mice.
Published 2013“…Proposed model in which FHL2 silencing using shFHL2 in murine osteosarcoma cells attenuates Wnt/β-catenin signaling and reduces the expression of Wnt5a and Wnt10b and possibly other FHL2 target genes in the tumors, resulting in decreased osteosarcoma cell growth, invasiveness and tumorigenesis <i>in vivo</i> (D).…”
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66453
Western blot analysis of claudin-1 and occludin expression after apical treatment with TGFβs.
Published 2013“…<p>A: Western blot with lysates of MEPC5 after apical stimulation with TGFβ1, TGFβ2 or TGFβ3 compared to untreated cells. …”
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66454
The Fuglevand model can overestimate the contribution of motor noise to force variability.
Published 2021“…F) CoV of force for the entire population as a function of mean force levels. …”
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66455
Sorafenib enhanced expression of osteopontin, an AP-1 target gene, in human hepatoma cell lines.
Published 2017“…<p>(A, B) Knockdown of c-Jun decreased expression of osteopontin after 48 hours of transfection into PLC/PRF/5 cells with siRNA against c-Jun (si-c-Jun) or si-control (si-C). …”
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66456
High 22G RNA levels are associated with low mRNA expression, compatible with silencing.
Published 2019“…<p>A) Mean normalized mRNA [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007905#pgen.1007905.ref055" target="_blank">55</a>] and 22G RNA reads detected in hermaphrodite and male gonads (data in 20 bins according to 22G RNA level; number of genes per bin: 4–1101 in hermaphrodites, 5–1343 in males; mean: solid line, outliers: circles). mRNA expression is globally decreased for the top 5% of genes (shaded area) with high levels of 22G RNA. …”
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66457
The TrkB was expressed in neurons in the injured brain and treatment with 7,8-dihydroxyflavone attenuated stretch-induced cytotoxicity and apoptosis in primary cultured neurons.
Published 2014“…<b>(E)</b> Western blot analysis of apoptosis-related proteins (cleaved caspase-3, Bcl-2, and Bax) shows that 5 µM DHF significantly decreased the cleaved caspase-3 level and the Bcl2/Bax ratio. …”
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66458
Differential sensitivity to PI3K/AKT pathway regulation is lost in isolated cancer cells.
Published 2013“…Proliferation assay (<sup>3</sup>H-thymidine incorporation) in primary C4-HD (left) or C4-HI (right) cells incubated during the last 48 hrs with 0.01 µM MPA and 5, 10 and 20 µM PD98059 or LY294002. For the combined treatment, the inhibitor was used at a dose of 10 µM. …”
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66459
<i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality...
Published 2020“…One QSAR model with best <math><msubsup><mrow><mi>R</mi></mrow><mrow><mi>calibration</mi></mrow><mrow><mn>2</mn></mrow></msubsup></math> = 0.8638 for split 2 was considered as the leading model. A greater value of cRp<sup>2</sup> <i>i.e.</i> 0.5 for all models in Y-randomization test showed the robustness of developed models. …”
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66460
Genetic analysis of CRISPR-Cas9 mediated re-sensitization of <i>K. michiganensis</i> (KM).
Published 2025“…Fold change <i><i>bla</i></i><sub>KPC</sub> gene expression. A significant reduction was observed in the re-sensitized cells KM<sup>S</sup> likely due to a decrease in <i><i>bla</i></i><sub>KPC</sub> gene copy number, as seen in 3C. 3E. …”