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RASSF3-induced apoptosis is p53 dependent.
Published 2013“…Absorbance was read at 570 nm and the average was calculated for 3 wells. p53 suppression blocked the effect of RASSF3 on cell proliferation, and p53 overexpression showed a similar effect to RASSF3. (D) Apoptosis in GH3 cells was measured by Annexin V/PI staining following Lenti-p53 shRNA transfection of Lenti-RASSF3-transfected GH3 cells, and Lenti-p53 transfection of Lenti-RASSF3 shRNA-transfected GH3 cells. …”