Image_1_Vitamin C Deficiency in Patients With Acute Myeloid Leukemia.jpeg by Tiziana Ottone (10101109)

“…Conversely, vitamin C concentration was significantly lower in AML as compared to HDs (p<0.0001), inversely correlated with peripheral blast‐counts (p=0.029), significantly increased at the time of complete remission (CR) (p=0.04) and further decreased in resistant disease (p=0.002). Expression of the main vitamin C transporters SLC23A2, SLC2A1 and SLC2A3 was also significantly reduced in AML compared to HDs. …”

Hhat KD inhibits Hh-mediated juxtacrine/paracrine signaling. by Antonios D. Konitsiotis (532086)

“…<p>A. Hhat-#2 siRNA KD in A549 cells was assessed by qPCR 24–96 h after siRNA transfection showing 20–60% decrease in Hhat mRNA expression. …”

Fusion-Activated Ca²⁺ Entry: An “Active Zone” of Elevated Ca²⁺ during the Postfusion Stage of Lamellar Body Exocytosis in Rat Type II Pneumocytes by Pika Miklavc (247760)

“…[Ca²⁺]_c increase followed with a delay of ∼0.2–0.5 s (method-dependent) and in the majority of cases this signal propagated throughout the cell (at ∼10 µm/s). …”

Image_3_Vitamin C Deficiency in Patients With Acute Myeloid Leukemia.jpeg by Tiziana Ottone (10101109)

“…Conversely, vitamin C concentration was significantly lower in AML as compared to HDs (p<0.0001), inversely correlated with peripheral blast‐counts (p=0.029), significantly increased at the time of complete remission (CR) (p=0.04) and further decreased in resistant disease (p=0.002). Expression of the main vitamin C transporters SLC23A2, SLC2A1 and SLC2A3 was also significantly reduced in AML compared to HDs. …”

DataSheet1_Preliminary study on mesenchymal stem cells in repairing nerve injury in pelvic floor denervation.DOCX by Guorui Zhang (6819536)

“…</p><p>Methods: MSCs were isolated from human adipose tissue and cultured. A MSCs suspension (40 µL at 5 × 107/mL) was loaded on a gelatin scaffold. …”

Atherosclerosis development is reduced with virgin pumpkin seed oil. by Martine C. Morrison (800552)

“…B: Morphometric analysis of lesion area revealed a significant decrease in atherosclerotic lesion area by REF and VIR. …”

Amphetamine-Induced Displacement of [¹¹C]FLB 457 Binding Potential. by Rajesh Narendran (304516)

“…<p>The bar graph shows [¹¹C]FLB 457 BP_ND under baseline (white bars) and post-amphetamine (black bars) conditions in n = 31 healthy subjects. Amphetamine led to a significant decrease in five of the eight cortical regions of interest (* denotes p < 0.05, paired t-tests) consistent with previous reports [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157867#pone.0157867.ref009" target="_blank">9</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157867#pone.0157867.ref011" target="_blank">11</a>].…”

Pathway analysis of arginine and proline metabolism. by Jie Meng (152665)

“…A red rectangle indicates increased expression genes compared with salt 30, while blue indicates decreased expression of genes, and the gray rectangle indicates no significant changes. …”

Pathway analysis of glycine metabolism. by Jie Meng (152665)

“…A red rectangle indicates increased expression compared with salt 30, and blue indicates decreased expression compared with salt 30. …”

Altered Hematopoiesis in Mice Lacking DNA Polymerase μ Is Due to Inefficient Double-Strand Break Repair by Daniel Lucas (13351)

“…In Polμ^−/− mice, hematopoietic development was defective in several peripheral and bone marrow (BM) cell populations, with about a 40% decrease in BM cell number that affected several hematopoietic lineages. …”

Significance of the Wnt canonical pathway in radiotoxicity <i>via</i> oxidative stress of electron beam radiation and its molecular control in mice by Shashank Kumar (8916584)

“…Post-irradiation likewise influences the morphology of sperm. The decrease in mRNA levels of Lef1, Axin2, Survivin, Ku70, and XRCC6 levels suggests radiation inhibits the Wnt canonical pathway and failure in DNA repair mechanisms in a coupled manner. …”

4-methylthiobutyl isothiocyanate synergize the antiproliferative and pro-apoptotic effects of paclitaxel in human breast cancer cells by Harneetpal Kaur (13973217)

“…In western blot experiment, the combination had a significant decrease in Bcl-xl protein level, whereas a higher level of p53, cleaved caspase-3, and cleaved caspase-9 proteins compared to individual treatment in <i>T</i>-47D cells. …”

The role of TCTP and CSN4 in the control of CULLIN neddylation and cell proliferation is conserved in <i>Drosophila</i>. by Léo Betsch (6273707)

“…<b>(g)</b> Impaired larval development is associated with a decrease of the CUL1^NEDD8 abundance in the <i>tub</i>><i>dTCTPi</i> compared to <i>tub</i>-GAL4. …”

Als acts downstream of GSK3β and upstream of SCF/Slimb/βTRCP E3 Ub ligase. by Gerlinde Reim (654594)

“…Combined <i>als</i> and <i>ter94</i> depletion caused an elevation of <i>wf</i> (lane 2) or a decrease of <i>arr</i> (lane 5). No alteration was observed for the Hh target gene <i>ptc</i> (lanes 7–9). …”

Illustration of the time course of the protocol by Qin Lu (995)

“…The lower panel represents the time course of the protocol for 7 patients for whom a CT scan and P–V curve in ZEEP were acquired after 15 minutes of mechanical ventilation without PEEP. …”

Pantothenate metabolism. by Patricia Kuzaj (635687)

“…<p>(a) Measurements of pantothenate by LC-MS/MS in positive ionization mode (patient/control ratio:0.5, p<0.0003). …”

Computational analysis of cell contact area in IRM images. by Daniel J. Modulevsky (307313)

CTV data with AS-3 buffer pH gradient. by Mitchell R. H. Weigand (11383844)

“…<p>A sample from donor F1 was measured using AS-3 as the RBC storage solution at five different pH values. …”

9.2.27PE in combination with ABT-737 causes synergistic cell cytotoxicity in melanoma cells. by Karianne Risberg (207221)

“…<p>(A) The 9.2.27PE immunotoxin caused a time- and dose dependent decrease of cell viability in melanoma cells. …”

Lipolytic treatment decontaminated the adipocytes, inducing an accumulation of PCB congeners in the extracellular medium. by Caroline Louis (332423)

“…An important drop of cell PCB proportions was observed during the first 6 hours of lipolysis (<i>p</i><0.001) and was followed by a more moderate decrease of the cell PCB percentages during the last 6 hours (<i>p</i><0.001). …”