Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice by Guillaume P. Dugué (620333)

“…<div><p>The inhibition of sensory responsivity is considered a core serotonin function, yet this hypothesis lacks direct support due to methodological obstacles. We adapted an optogenetic approach to induce acute, robust and specific firing of dorsal raphe serotonergic neurons. …”

(R)-albuterol decreases cytokine mRNA levels in activated T cells by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”

<i>btuE</i> expression results in decreased intracellular ROS. by Felipe A. Arenas (23050)

Fig 11 - by Jianbo Jia (717814)

Fig 17 - by Jianbo Jia (717814)

The image illustrates the five steps of the experiment. by Deborah Ribeiro Frazão (9188152)

PKA signaling stimulated by the combination of isoproterenol and IBMX is decreased by the absence of insulin. by Craig A. Eyster (9262632)

“…Scale bar 10μm. (B) Quantitation of mean fluorescence intensity (MFI) for PKA-substrate are presented as whisker plots that encompass data from at least 18 cells, as detailed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0231806#pone.0231806.g001" target="_blank">Fig 1</a> (n = 3 biological replicates, and at least 6 cells per experiment). (*) Isoproterenol and IBMX treatment caused a significant increase (<i>p</i> < .001) compared to IBMX alone in all conditions. (‡) stimulated Akita and WT–ins conditions are significantly decreased compared to matching WT +ins conditions. …”

Decreased Tks5 expression results in neural crest-derived defects. by Danielle A. Murphy (212554)

Phosphorylation of PFK2 is decreased in cardiomyocytes cultured in the absence of insulin and with diabetes. by Craig A. Eyster (9262632)

“…Scale bar 10μm. (B) Quantitation of mean fluorescence intensity (MFI) for pPFK2 are presented as whisker plots that encompass data from at least 18 cells, as detailed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0231806#pone.0231806.g001" target="_blank">Fig 1</a> (n = 3 biological replicates, and at least 6 cells per experiment). (*) IBMX or Isoproterenol treatment causes a significant increase (<i>p</i> < .001) compared to untreated WT cells; (†) Each WT (-ins) condition is significantly decreased (<i>p</i> < .001) compared to WT (+ins); (‡) all Akita conditions are significantly decreased (<i>p</i> < .001) compared to comparable WT conditions. …”

(A) Monthly averaged mean temperature (°C) and (B) monthly accumulated precipitation (mm) measured in Oulanka research station during the years of the study. by Sandra Varga (405097)

Mean (Standard Deviation) at baseline and follow-up for strength. by Elora C. Brenneman (795723)

Mean TOC concentration and mean bacterioplankton abundance for Sargasso Sea and Santa Barbara Channel CNP- and natural-DOC experiments. by Anna K. James (3812875)

UGGT activity decreases in <i>uggt-1(RNAi)</i> worms but no decrease was observed in <i>uggt-2 (RNAi)</i> worms. by Lucila I. Buzzi (198284)

Decreased brain-derived neurotrophic factor plasma levels in psoriasis patients by A.R. Brunoni (5694239)

Diabetes and TPEN treatment decreased the expression of Nrf2 that was associated with decreased Akt and GSK-3β phosphorylation and nuclear accumulation of Fyn. by Chi Zhang (9857)

The mean accuracy of the BVRT between under control (gray) and rTMS (black), for the design 1–3 (Simple), the designs 4–7 (Medium) and the designs 8–10 (Complex). by Nakako Okamoto (18501452)

NDP-MSH decreases Pam₃CSK₄-induced microglial phagocytosis of latex beads. by Lila Carniglia (348123)

GIRK2^AgRP-KO mice show decreased EE associated with BAT dysfunction and decreased sympathetic activity. by Youjin Oh (3308670)

Mean pace of decrease in mortality rates for White (front row) and Black (back row) women for the thirteen U.S. states from 1975 through 2010. by Mohammad A. Tabatabai (630217)

Sensitivity of the PCR for decreasing concentrations of genomic DNA purified from <i>Veillonella</i> species using species-specific primer sets. by Izumi Mashima (3165120)