Soluble plantain NSP increases the transmucosal short circuit current of <i>ex vivo</i> human ileal follicle-associated epithelium. by Bryony N. Parsons (469436)

“…<p>Plantain NSP (5 mg/mL) significantly increased (<b>A</b>) transmucosal short circuit current (<i>I_sc</i>), with a concomitant decrease in (<b>B</b>) epithelial potential difference (PD, apical-side negative), during pre-treatment of, and blockade of translocation of S. …”

Summary of anxiogenic and anxiolytic modulation of adult zebrafish behavior in standard 6-min novel tank test (see Fig. S1 in Supplementary Materials for raw data from these experi... by Jonathan Cachat (377024)

“…Reference anxiolytic treatments include chronic fluoxetine (100 µg/L for 2 weeks), chronic ethanol (0.3% vol/vol for 1 week), chronic morphine (1.5 mg/L for 2 weeks) and acute nicotine (10 mg/L for 5 min). Statistically significant differences from matched controls (p<0.05, U-test) are represented by solid arrows (empty arrows denote trends; p = 0.05–0.085, U-test): up – increase, down – decrease; empty fields indicate no significant effects, n/a – data not available. …”

Data from: Loss-of-function mutations in the fruit softening gene POLYGALACTURONASE1 doubled fruit firmness in strawberry by Nicolas P. Jimenez (22079510)

cPLA₂α^-/- sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca²⁺ current inhibition by M₁ muscarinic recept... by Liwang Liu (424650)

“…To determine cPLA₂α’s functional importance more globally, we examined action potential firing of cPLA₂α^+/+ and cPLA₂α^-/- SCG neurons, and found decreased latency to first firing and interspike interval resulting in a doubling of firing frequency in cPLA₂α^-/- neurons. …”

Age-specific adult abundance and adult recruitment across temperature. by Lindsay M. Beck-Johnson (485193)

Image_1_Changes in Soil Chemistry After 17 Years in Urban and Rural Forest Patches.pdf by Ian Yesilonis (7482125)

“…Calcium increased by 35% from 622 to 844 mg kg^–1, pH increased from 4.1 to 4.5, and C:N ratios decreased from 17.8 to 16.7. …”

Clinical and biochemical data for Subject 11 (Dose Limiting Toxicity; DLT). by Ryszard M. Pluta (233325)

Case. by Young Hyo Kim (782568)

Survival rate of grafted cells at 3, 7, 14, 28 and 70 days after transplantation of MSCmix/NCSCmix in MPTP and control mice. by PLOS ONE (2189197)

Mini-TyrRS treatment after coronary ligation improves myocardial function <i>in vivo</i>. by Margaret E. McCormick (641390)

KGFR/FGFR2b depletion inhibits early differentiation in keratinocytes. by Francesca Belleudi (233982)

“…The quantitative analysis was assessed as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0024194#pone-0024194-g002" target="_blank">figure 2D</a>. …”

Figure S1 - Interplay between Pleiotropy and Secondary Selection Determines Rise and Fall of Mutators in Stress Response by Muyoung Heo (251767)

“…The green lines at t = 20000 mark the time of stresses, which are (A) temperature increase, (B) 3 fold decrease of the base birth rate (<i>b</i>₀) (stationary phase), and (C) 10 fold drop of the optimal total concentration (<i>C</i>₀) of all proteins (starvation). …”

Regional changes of FA values as revealed by TBSS after HDBR. by Ke Li (106849)

NMDAR-dependent coordination between clusters supports network encoding improvement. by Kaspar Podgorski (110778)

La protein expression promotes proliferation and cell cycle progression of SCC 22B cells. by Gunhild Sommer (13580)

DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε by Celine S. Weiss (453817)

“…</p><p>Results</p><p>(1) Under baseline conditions eIF2Bε transgenic mice showed no difference in cardiac phenotype compared to wild type, whereas in the mutant eIF2Bε-S⁵³⁵A an increase in LV/tibia length (7.5±0.4 mg/mm vs. 6.2±0.2 mg/mm, p<0.001) and cardiomyocyte cross sectional area (13004±570 vs. 10843±347 RU, p<0.01) was observed. (2) Cardiac overexpression of eIF2Bε did not change the response of the heart to pathologic stress induced by chronic isoproterenol treatment. (3) Cardiac overexpression of the eIF2Bε transgene was followed by overexpression of DYRK2 which is known to prime the inhibitory action of GSK-3β on eIF2Bε, while DYRK1A and GSK-3β itself were not increased. (4) In C57BL/6 mice after 48 h of isoproterenol-stimulation or aortic banding, eIF2Bε was increased and DYRK2 was concomitantly decreased. (5) In line with these in vivo findings, siRNA knockdown of DYRK2 in cultured cardiomyocytes resulted in decreased levels of p(S535)- eIF2Bε, (6) whereas adenoviral induced overexpression of DYRK2 was accompanied by clearly increased phosphorylation of eIF2Bε, indicating a coordinated response pattern (7) Adenoviral induced overexpression of DYRK2 leads to significantly reduced cardiomyocyte size and diminishes hypertrophic response to adrenergic stimulation.…”

Wild-caught flies maintain particular <i>Acetobacter</i> species in the gut. by Inês S. Pais (5484470)

“…<p>Total levels of Acetobactereaceae (A, E) and <i>Lactobacillus</i> (C, G) in laboratory <i>w</i>^<i>1118</i> <i>iso</i> (A, C) and in wild-caught flies (E, G) before (Day 0) and after 10 days of the stability protocol (Day 10). …”

Selective Loss of Early Differentiated, Highly Functional PD1^high CD4 T Cells with HIV Progression by Robert M. Paris (237340)

“…In line with an increased susceptibility to HIV infection, PD-1 expression in this CD4 T cell subset was associated with increased activation and expression of the HIV co-receptor, CCR5. Rather than exhaustion, this population produced more IFN-g, MIP1-a, IL-4, IL-10, and IL-17a compared to PD-1^low EI CD4 T cells. …”

Effectiveness of Self-Help plus and problem management plus interventions in providing psychological support to clients of Opioid Agonist treatment programs in Ukraine by Viktoriia Gorbunova (21728671)

Microglial migration increases long after the electrical silence associated with spreading depression. by Yelena Y. Grinberg (223907)