Image 4_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.tif by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Image 2_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.tif by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Table 3_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.docx by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Table 1_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.docx by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

DataSheet_2_Circulating Brain-Derived Neurotrophic Factor, Antioxidant Enzymes Activities, and Mitochondrial DNA in Bipolar Disorder: An Exploratory Report.docx by Dong Wang (73290)

“…Unexpectedly, we observed no significant correlation between mtDNA content and BDNF in BD patients (p > 0.05).…”

Image 1_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.tif by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Table 4_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.docx by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Table_1_Physiological and transcriptome analysis of Candida albicans in response to X33 antimicrobial oligopeptide treatment.doc by Qunlin Lu (11788121)

“…The evolution of its drug-resistant mutants necessitate an urgent development of novel antimicrobial agents.</p>Results<p>Here, we explored the antimicrobial activity and inhibitory mechanisms of X33 antimicrobial oligopeptide (X33 AMOP) against C. albicans. …”

Image 3_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.tif by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Table 2_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.docx by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

S6 Fig - by Nikhita Pasnuri (14559917)

“…In GMR-Gal4 driving <i>spitz</i> dsRNA, patterned Elav and dpERK staining is lost. (B) Mean Intensities of dpERK in a fixed ROI is plotted here clearly showing the decreased dpERK staining when Elav or GMR-Gal4 drives <i>spitz</i> dsRNA. (*** indicates p-values < 0.001 in a Student’s t-test). …”

<i>nhr-62</i> modulates DR-induced fat metabolism. by Bree N. Heestand (437346)

“…See <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003651#pgen.1003651.s003" target="_blank">Figure S3</a> for physiologic traits of <i>nhr-62</i> mutation. …”

Image_2_Systemic Oxidative Stress, Aging and the Risk of Cardiovascular Events in the General Female Population.TIFF by Martin F. Bourgonje (10115305)

“…<p>Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free thiols (R-SH, sulfhydryl groups), which are key components of the extracellular antioxidant machinery. …”

Image_3_Systemic Oxidative Stress, Aging and the Risk of Cardiovascular Events in the General Female Population.TIFF by Martin F. Bourgonje (10115305)

“…<p>Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free thiols (R-SH, sulfhydryl groups), which are key components of the extracellular antioxidant machinery. …”

Data_Sheet_1_Systemic Oxidative Stress, Aging and the Risk of Cardiovascular Events in the General Female Population.docx by Martin F. Bourgonje (10115305)

“…<p>Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free thiols (R-SH, sulfhydryl groups), which are key components of the extracellular antioxidant machinery. …”

Image_1_Systemic Oxidative Stress, Aging and the Risk of Cardiovascular Events in the General Female Population.TIFF by Martin F. Bourgonje (10115305)

“…<p>Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free thiols (R-SH, sulfhydryl groups), which are key components of the extracellular antioxidant machinery. …”

Focused operations to improve the patient flow in full-service healthcare organisations by Philip Åhlin (15257749)

Supplementary Material for: Retinocytoma: clinical and genetic characteristics in 16 pediatric and adult cases by figshare admin karger (2628495)

Pedogenesis of high-mountain soils from Serra da Mantiqueira, Brazil by Rafael Cipriano da Silva (4617679)

“…Isotopic analyses of 13C were performed in soil samples collected at depths of 10, 20, 30, 40, 50, 60, 80 and 100 cm; except in P2, which was collected up to 60 cm deep. …”

Supplementary file 1_The relationship between frailty in older adults and anxiety and depression in china: propensity score matching and network analysis.docx by Yinglin Li (9699235)

“…</p>Conclusion<p>NCT results showed no significant difference in the network structure of anxiety and depression between frail elderly and control groups. A slight decrease in network strength was observed in non-frail elderly but was not statistically significant. …”