Effects of plant diversity on productivity strengthen over time due to trait-dependent shifts in species overyielding by Liting Zheng (17905028)

“…<p dir="ltr">Using data from 65 grassland and forest biodiversity experiments, we show that the temporal strength of diversity effects at the community scale is underpinned by temporal changes in the species that yield. …”

Table_1_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.docx by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Image_3_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.tif by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Image_4_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.tif by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Image_2_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.tif by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Image_1_Attenuated T Cell Responses Are Associated With the Blockade of Cerebral Malaria Development by YOP1-Deficient Plasmodium berghei ANKA.tif by Lei Hai (10754010)

“…Here, we show that protection from ECM in Pbyop1Δ-infected mice is associated with reduced intracerebral Th1 accumulation, decreased expression of pro-inflammatory cytokines and chemokines, and attenuated pathologies in the brainstem, though the total number of CD4⁺ and CD8⁺ T cells sequestered in the brain are not reduced. …”

Investigation of the radiosensitization effect of DNA polymerase theta inhibition in homologous recombination proficient and deficient human breast cancer and fibrosarcoma cells by Natalie West (16549035)

“…While the dose required to reach 10% cell survival was unchanged in the wild type cells, the dose decreased by 2 Gy for the HR-deficient cells treated with the Polθ inhibitor. …”

Investigation of the radiosensitization effect of DNA polymerase theta inhibition in homologous recombination proficient and deficient human breast cancer and fibrosarcoma cells by Natalie West (16549035)

“…While the dose required to reach 10% cell survival was unchanged in the wild type cells, the dose decreased by 2 Gy for the HR-deficient cells treated with the Polθ inhibitor. …”

IDE-KO mice show age-dependent reductions in IR levels and insulin-stimulated glucose uptake that correlate with the onset of the diabetic phenotype. by Samer O. Abdul-Hay (249249)

“…Graphs show mean ± SEM of IR levels quantified by luminescent imaging (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020818#s4" target="_blank"><i>Materials and Methods</i></a>) and normalized to IR levels in 2-mo-old WT mice. …”

Comparison of average virus neutralization in adapted plaque reduction neutralization tests using liver homogenates of YFV-, MAYV-, and CHIKV-infected mice. by Thaís Alkifeles Costa (16024584)

“…Pairwise analyses indicated differences between all serial dilutions, with the decrease of average neutralization values with increasing dilutions (p< 1.0−6, A and B). …”

Avoided recurrences and costs with adjuvant atezolizumab for patients with early non-small cell lung cancer in Europe by Alastair Greystoke (9562178)

“…Immunotherapies such as atezolizumab may delay or prevent recurrence if given after surgery (known as “adjuvant” treatment) to appropriate patients, but the benefits for all suitable patients remain unclear. We developed a mathematical model based on clinical trials and real-world data that estimated ~5000 recurrences avoided over a 10-year period when adjuvant atezolizumab was available for eligible patients in 5 European countries. …”

Deletion of p38α ameliorates tubular but not glomerular damage during anti-GBM nephritis. by Ralf Müller (118397)

Divergent mtDNA suppresses type I interferon activation <i>in vivo</i>. by M. Isabel G. Lopez Sanchez (9499553)

“…Data are presented as mean ± SD, n = 12 mice (control) and n = 10 mice (xeno); <i>p</i> = 0.045 by unpaired, two tailed, Student’s <i>t</i>-test. …”

Diabetes increases vascular remodeling. by Roshini Prakash (282722)

Seizure changes during study phases. by Mark Bodner (33604)

“…Posterior density was obtained using Markov Chain Monte Carlo methods and implemented using the rjags package <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045303#pone.0045303-Plummer1" target="_blank">[45]</a> within the R computing environment <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045303#pone.0045303-R1" target="_blank">[46]</a>. …”

Effects of the activation and inhibition of NOTCH signalling on spinal cord progenitor cell proliferation and neuronal generation. by Barbara Hämmerle (36261)

“…<p>A–A′. Confocal projection over 50 µm at the level of the 12^th and 13^th somites of an HH13 embryo that was electroporated with NICD at stage HH10. …”

Dietary intake is associated with risk of multiple myeloma and its precursor disease by Marianna Thordardottir (5318183)

“…We additionally found that intake of fruit at least three times per week during the late life period was associated with decreased risk of progressing from MGUS to MM (HR = 0.34, 95% CI 0.13–0.89) when compared to lower intake. …”

Metabolic and Behavioral Compensations in Response to Caloric Restriction: Implications for the Maintenance of Weight Loss by Leanne M. Redman (170737)

“…</p><h3>Conclusions</h3><p>For the first time we show that in free-living conditions, CR results in a metabolic adaptation and a behavioral adaptation with decreased physical activity levels. …”

TGP treatment reduced the inhibitory neurotransmitter. by Feiye Zhu (2901245)

“…<p>The levels of NO (A), NOS (B) and VIP (C) in the MC group increased compared with that in the NC group, while they decreased after TGP treatment. …”

OPC-derived TGF-β1 and BBB integrity in vitro. by Ji Hae Seo (554736)

“…</b> OPC-CM increased in vitro BBB tightness (i.e. decreased permeability of endothelial monolayer), and the TGF-β-receptor signaling inhibitor SB431542 (10 µM) cancelled the effects of OPC-CM. …”