DataSheet_1_Effects of diet and temperature on the fatty acid composition of the gammarid Gammarus locusta fed alternative terrestrial feeds.docx by Alberto Ribes-Navarro (9973753)

“…The temperature had no effect on biomass, although high temperature (20°C) resulted in a decrease in survival. The effects of temperature on the gammarid fatty acids were not evident, with diet being the main modulator of the profiles. …”

Protein population variation with reversible chaperone binding. by Aidan I. Brown (10063385)

“…Two regimes are shown, corresponding to two curves shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008654#pcbi.1008654.g003" target="_blank">Fig 3B</a>. …”

Autocrine Production of β-Chemokines Protects CMV-Specific CD4⁺ T Cells from HIV Infection by Joseph P. Casazza (257693)

“…<div><p>Induction of a functional subset of HIV-specific CD4⁺ T cells that is resistant to HIV infection could enhance immune protection and decrease the rate of HIV disease progression. …”

Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Image_1_Piperine Attenuates TBI-Induced Seizures via Inhibiting Cytokine-Activated Reactive Astrogliosis.pdf by Yabei Song (8931530)

“…Specific-pathogen-free-grade mice were randomly divided into six dietary groups for a week: control group, TBI group, three piperine groups (low PPR group with 10 mg/kg PPR, medium PPR group with 20 mg/kg PPR, and high PPR group with 40 mg/kg PPR), and a positive control group (200 mg/kg valproate). …”

Inclusion of evolutionary information greatly increases the specificity and selectivity of CRM searches based on binding-site clustering by Benjamin P Berman (1456)

“…The number of false positives is not strictly monotonically decreasing with an increasing binding site cutoff. This stems from the cluster merging behavior of CIS-ANALYST - sometimes a decrease in the minimum number of sites leads CIS-ANALYST to tack on a lower-density cluster that is adjacent to a higher-density one, resulting in a single cluster with more sites but lower site density. …”

Data Sheet 1_Propionic acid supplementation promotes the expansion of regulatory T cells in patients with end-stage renal disease but not in renal transplant patients.pdf by Moritz Anft (11995520)

“…Our data suggest that dietary supplements containing propionate might have a beneficial effect decreasing systemic inflammation in dialysis patients through Treg expansion. …”

Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Deciphering the Developmental Dynamics of the Mouse Liver Transcriptome by Sumedha S. Gunewardena (817801)

“…The average expression of growth factors peak between Day-3 and Day-10, and decrease thereafter. We identified critical biological functions, upstream regulators, and putative transcription modules that seem to govern age-specific gene expression. …”

Impacts of <i>Metarhizium brunneum</i> F52 infection on the flight performance of Asian longhorned beetles, <i>Anoplophora glabripennis</i> by Eric H. Clifton (7354049)

“…The maximum observation for total flight distance was a healthy male that flew 10.9 km in 24 hours on a flight mill. …”

Data Sheet 1_Stellate ganglion blockade under ultrasound-guidance and the physiological responses in the rat.pdf by Robert M. N. Tran (20539130)

“…Heart rate variability analysis showed that SGB with lidocaine on the right or left side caused a decrease in the ratio of the power of low-frequency over high-frequency. …”

Image_1_Cyclophilin Inhibitor NV556 Reduces Fibrosis and Hepatocellular Carcinoma Development in Mice With Non-Alcoholic Steatohepatitis.tiff by Joseph Kuo (244331)

“…Here, we investigated whether NV556, a cyclophilin inhibitor derived from sanglifehrins, would decrease the development of NASH and HCC in a preclinical mouse model. …”

CXCR4 homodimerization vs. CXCR4 heterodimerization. by Elisabeth Steel (545397)

“…(n = 8, mean ± S.E.) When homogeneity of variance was not met, a Kruskal Wallis test was performed according to the method described by Zar <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0093646#pone.0093646-Vischer1" target="_blank">[6]</a>, in which a significant effect of receptor pair on biotinylation signal was found (Hc = 19.84) considered for the critical value X²(2) = 14.067 (p<0.05, ν = 7). …”

Avoided recurrences and costs with adjuvant atezolizumab for patients with early non-small cell lung cancer in Europe by Alastair Greystoke (9562178)

“…Immunotherapies such as atezolizumab may delay or prevent recurrence if given after surgery (known as “adjuvant” treatment) to appropriate patients, but the benefits for all suitable patients remain unclear. We developed a mathematical model based on clinical trials and real-world data that estimated ~5000 recurrences avoided over a 10-year period when adjuvant atezolizumab was available for eligible patients in 5 European countries. …”

Pharmacological blockade of K_ATP channels negates the hippocampal synaptic and neuronal protection afforded by ketones. by Do Young Kim (131974)

“…Asterisks denote significant differences between experimental groups and the control at a specific time-point (*** <i>p</i> < 0.001). The dotted line indicates the mean PS amplitude of the control group. …”

Dose-dependent Inhibition of SNAT4 Transport Activity by DTT and TCEP. by Rugmani Padmanabhan Iyer (381482)

“…<p>Xenopus oocytes expressing wild type SNAT4 were preincubated with DTT (0–10 mM) (A) or TCEP (0–10 mM) (B) for 30 min. [³H] L-alanine uptake assay was then performed in the presence of DTT or TCEP. …”

Metabolic and Behavioral Compensations in Response to Caloric Restriction: Implications for the Maintenance of Weight Loss by Leanne M. Redman (170737)

“…</p><h3>Conclusions</h3><p>For the first time we show that in free-living conditions, CR results in a metabolic adaptation and a behavioral adaptation with decreased physical activity levels. …”

SAP inhibits HMWHA-induced fibrocyte differentiation and potentiates LMWHA-induced fibrocyte inhibition. by Anu S. Maharjan (342245)

“…After 5 days, the cells were air dried, fixed, stained, and the number of fibrocytes was counted. The results are mean ± SEM of fibrocytes per 2.5×10⁵ PBMC (n = 5 separate experiments, except n = 11 separate experiments for HMWHA with no SAP). …”

Effects on increment and decrement bars are consistent with effects on gratings. by Markku Kilpeläinen (356137)

Comparison of average virus neutralization in adapted plaque reduction neutralization tests using liver homogenates of YFV-, MAYV-, and CHIKV-infected mice. by Thaís Alkifeles Costa (16024584)

“…Pairwise analyses indicated differences between all serial dilutions, with the decrease of average neutralization values with increasing dilutions (p< 1.0−6, A and B). …”