Fig 4 - by Melinda Liu Perkins (6116204)

“…The local front velocity calculated from <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008589#pcbi.1008589.e047" target="_blank">Eq (13)</a> rapidly decreases posterior to the critical point but remains strictly positive, indicating that a bistable gene expression boundary will propagate posteriorly. …”

Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6 by André Fischer (5706887)

“…In this study, starting from the crystal structure, we built a full-length membrane-anchored all-atom model of the wild-type CYP2D6 as well as five of its variants differing in the enzymatic activity. …”

Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6 by André Fischer (5706887)

“…In this study, starting from the crystal structure, we built a full-length membrane-anchored all-atom model of the wild-type CYP2D6 as well as five of its variants differing in the enzymatic activity. …”

Molecular Dynamics Simulations Reveal Structural Differences among Allelic Variants of Membrane-Anchored Cytochrome P450 2D6 by André Fischer (5706887)

“…In this study, starting from the crystal structure, we built a full-length membrane-anchored all-atom model of the wild-type CYP2D6 as well as five of its variants differing in the enzymatic activity. …”

DataSheet1_Dose Optimization of Aditoprim-Sulfamethoxazole Combinations Against Trueperella pyogenes From Patients With Clinical Endometritis by Using Semi-mechanistic PK/PD Model.... by Muhammad Kashif Maan (5155973)

“…In the in vitro PK/PD model, the dosage proportion of sulfamethoxazole 4 mg/ml twice a day in combination with steady-state aditoprim 1 mg/ml efficiently repressed the growth of bacteria in 24 h with the ratio of 2-log10 decrease, related to the early inoculum against three T. …”

Table_1_Mushroom Bulgaria inquinans Modulates Host Immunological Response and Gut Microbiota in Mice.DOCX by Hongzhen Sang (9472826)

“…Furthermore, BI inhibited the production of IL-2 in anti-CD3/CD28-stimulated T cells from mLN in a dose-dependent manner. Meanwhile, BI at 2%, not 1% inhibited the production of IL-4, IL-10, and IFN-γ of mLN. …”

Rel-mediated inhibition of the JNK-FAO axis is essential for progenitor maintenance. by Parvathy Ramesh (12571120)

“…<p>(A-B) Increase in <i>whd</i> transcripts level upon progenitor-specific Rel downregulation (A) (N = 3, P-values: = 0.0121, whereas overexpression (B) caused a decrease in <i>whd</i> level (N = 3, P-value: = 0.0101). …”

Human Surfactant Protein D Alters Oxidative Stress and HMGA1 Expression to Induce p53 Apoptotic Pathway in Eosinophil Leukemic Cell Line by Lakshna Mahajan (504239)

“…This approach identified large scale molecular changes initiated by SP-D in a human cell for the first time. Among others, the proteomics analysis highlighted a decreased expression of survival related proteins such as HMGA1, overexpression of proteins to protect the cells from oxidative burst, while a drastic decrease in mitochondrial antioxidant defense system. rhSP-D mediated enhanced oxidative burst in AML14.3D10 cells was confirmed, while antioxidant, N-acetyl-L-cysteine, abrogated the rhSP-D induced apoptosis. …”

Video 1_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”

Video 2_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”

Video 3_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”

Video 4_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”

Data Sheet 1_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.docx by Katrina Knight (17391604)

“…The porosity of all MUSs significantly decreased with loading (p-values < 0.001); except for ArcTV with the stabilizing suture which showed the least amount of deformation (i.e., percent change in porosity decreasing by only 14%, p < 0.001, at 10 N).…”

Image_3_Saracatinib synergizes with enzalutamide to downregulate AR activity in CRPC.jpg by Ralph E. White (8599362)

“…We observed robust synergy between the SRC kinase inhibitor, saracatinib, and enzalutamide, in the AR-FL+/AR-V+ CRPC cell lines, LNCaP95 and 22Rv1. …”

Table 1_Intergenerational education mobility in India: nonlinearity and the Great Gatsby Curve.docx by P. K. V. Kishan (19744606)

Image_1_Saracatinib synergizes with enzalutamide to downregulate AR activity in CRPC.jpg by Ralph E. White (8599362)

“…We observed robust synergy between the SRC kinase inhibitor, saracatinib, and enzalutamide, in the AR-FL+/AR-V+ CRPC cell lines, LNCaP95 and 22Rv1. …”

Image_2_Saracatinib synergizes with enzalutamide to downregulate AR activity in CRPC.jpg by Ralph E. White (8599362)

“…We observed robust synergy between the SRC kinase inhibitor, saracatinib, and enzalutamide, in the AR-FL+/AR-V+ CRPC cell lines, LNCaP95 and 22Rv1. …”

Structure diagram of mobile and hitching base. by Liang Ge (541067)

“…The experimental results show that: (1) The liquid volume in a tank of vacuum degree within 2.0 Pa and 200 mm interlayer reduced no more than 15.5% after 48 days; (2) Taking the pressure in the tank as the power source, because of environmental differences inside and outside the pipe after 100 m pressure holding delivery, the physical form of liquid and gas could be converted instantly; (3) The continuous discharge time without ice blocking for a tank full of 2 m³ liquid was about 10.5 min under 25 L dual mode nitrogen pressurization, which is 1/12 of injection time after ground gasification; (4) Based on the temperature decrease trend measured at different positions, the cooling characteristics on liquid gasification jet path are quantified, and the calculation formula of temperature changing with time on the center line of liquid gasification jet is obtained. …”

Association of insulin receptor substrate 1 (<i>IRS-1</i>) gene polymorphism with growth and litter-related traits in NMER rabbits by Naglaa Fathy Megahed (16323949)

“…Additionally, the genotypic and allelic frequencies, the effective (<i>N_e</i>) and observed (<i>N_A</i>) numbers of alleles, observed (<i>H_o</i>) and expected (<i>H_e</i>) heterozygosity, Hardy-Weinberg equilibrium (HWE), and the decrease in heterozygosity because of inbreeding (<i>F_IS</i>) were calculated. …”

Synthesis of Poly(decahydro-2-naphthyl methacrylate)s with Different Geometric Structures and Effects of Side-Group Dynamics on Polymer Properties Investigated by Thermal and Dynam... by Anri Ozaki (1967302)

“…An increase in the DNMA-II content in the repeating units accelerated a dynamic conformation change, resulting in a decrease in the tan δ peak temperature and the activation energy value, as well as the glass transition temperature of the polymers. …”