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146641
Channelrhodopsin (ChR2)-mediated optic stimulation robustly activated the MRR and altered behavior.
Published 2017“…Red and blue lines show iso-intensity lines of light penetration at 10% and 1% of release intensity, respectively (based on [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0181264#pone.0181264.ref018" target="_blank">18</a>]). …”
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146642
Table_6_Correlation between the intestinal microflora and peripheral blood Th1/Th2 balance in hypothyroidism during the first half of pregnancy.xlsx
Published 2023“…In contrast to the control group, the hypothyroidism group showed an increase in Th1 cells and the Th1/Th2 ratio, and a decrease in Th2 cells. The hypothyroidism group had higher serum IL-2, TNF-α, and IFN-γ levels, and lower IL-10 levels, than the control group. …”
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146643
Table_5_Correlation between the intestinal microflora and peripheral blood Th1/Th2 balance in hypothyroidism during the first half of pregnancy.xlsx
Published 2023“…In contrast to the control group, the hypothyroidism group showed an increase in Th1 cells and the Th1/Th2 ratio, and a decrease in Th2 cells. The hypothyroidism group had higher serum IL-2, TNF-α, and IFN-γ levels, and lower IL-10 levels, than the control group. …”
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146644
Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories
Published 2016“…Our results suggest that erosion of gene regulation by mutation load significantly contributes to observed heritable phenotypes that manifest in the medical history. The test we developed exposes a hitherto hidden layer of personal variants that promise to shed new light on human disease penetrance, expressivity and the sensitivity with which we can detect them.…”
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146645
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146646
Table2_Pan-cancer analysis identifies proteasome 26S subunit, ATPase (PSMC) family genes, and related signatures associated with prognosis, immune profile, and therapeutic response...
Published 2023“…Notably, they all shared a positive association with increased TMB, TIDE score, expression of immune checkpoints (CD276 and PVR), and more M1 macrophages but decreased B-cell abundance. A PSMC-based prognostic signature was established based on five hub genes derived from the differential expression clusters of PSMC genes, and it was used to dichotomize LUAD patients into high- and low-risk groups according to the median risk score. …”
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146647
Table4_Pan-cancer analysis identifies proteasome 26S subunit, ATPase (PSMC) family genes, and related signatures associated with prognosis, immune profile, and therapeutic response...
Published 2023“…Notably, they all shared a positive association with increased TMB, TIDE score, expression of immune checkpoints (CD276 and PVR), and more M1 macrophages but decreased B-cell abundance. A PSMC-based prognostic signature was established based on five hub genes derived from the differential expression clusters of PSMC genes, and it was used to dichotomize LUAD patients into high- and low-risk groups according to the median risk score. …”
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146648
Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary...
Published 2018“…Furthermore, panobinostat-treatment enhanced α-tubulin-acetylation, decreased the expression of survival-related genes Bcl-XL and <i>BIRC5</i>/survivin, and was associated with induction of ER stress and apoptosis in IPF-fibroblasts. …”
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146649
Table1_Pan-cancer analysis identifies proteasome 26S subunit, ATPase (PSMC) family genes, and related signatures associated with prognosis, immune profile, and therapeutic response...
Published 2023“…Notably, they all shared a positive association with increased TMB, TIDE score, expression of immune checkpoints (CD276 and PVR), and more M1 macrophages but decreased B-cell abundance. A PSMC-based prognostic signature was established based on five hub genes derived from the differential expression clusters of PSMC genes, and it was used to dichotomize LUAD patients into high- and low-risk groups according to the median risk score. …”
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146650
Table3_Pan-cancer analysis identifies proteasome 26S subunit, ATPase (PSMC) family genes, and related signatures associated with prognosis, immune profile, and therapeutic response...
Published 2023“…Notably, they all shared a positive association with increased TMB, TIDE score, expression of immune checkpoints (CD276 and PVR), and more M1 macrophages but decreased B-cell abundance. A PSMC-based prognostic signature was established based on five hub genes derived from the differential expression clusters of PSMC genes, and it was used to dichotomize LUAD patients into high- and low-risk groups according to the median risk score. …”
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146651
The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice
Published 2020“…Anti-PD-1 mAb treatment decreased PD-1+ CD8+ cell population by 32.3% after interruption of four weeks treatment, and D1143 co-treatment further reduced it from 32.3 to 73%. …”
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146652
Filamentous calcareous alga provides substrate for coral-competitive macroalgae in the degraded lagoon of Dongsha Atoll, Taiwan
Published 2019“…<i>divaricata</i> can persist for 3.5 years. Yet, <i>G</i>. <i>divaricata</i> provides substrate to other macroalgae (e.g., <i>Lobophora</i> sp.) that also limit the growth of corals.…”
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146653
Modulation of Brain Resting-State Networks by Sad Mood Induction
Published 2008“…Between the two states, we observed apparent increases and decreases in the overall functional connectivity of these networks. …”
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146654
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146655
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146656
Evaluation of platelet dense granules by transmission electron microscopy in healthy pediatric donors and pediatric patients with suspected platelet disorders
Published 2025“…</p> <p>Healthy donors (<i>n</i> = 77, 41.6% female), ages 3–18 years, had a mean of 2.7 DG/platelet (±0.5), ranging from 1.9 to 3.8 per platelet. The mean DG/platelet did not correlate with age or gender. …”
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146657
Table_1_The Effect of Kyolic Aged Garlic Extract on Gut Microbiota, Inflammation, and Cardiovascular Markers in Hypertensives: The GarGIC Trial.pdf
Published 2018“…High blood pressure has been linked to gut dysbiosis, with a significant decrease in microbial richness and diversity in hypertensives compared to normotensives. …”
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146658
Data_Sheet_1_Artemin Is Upregulated by TrkB Agonist and Protects the Immature Retina Against Hypoxic-Ischemic Injury by Suppressing Neuroinflammation and Astrogliosis.PDF
Published 2021“…The neuroprotective effects of ARTN were related to a decrease in microglial activation at P17 and attenuation of astrogliosis at P29. …”
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146659
Dynamic chloride accumulation compromises the effectiveness of inhibition during balanced distal synaptic input.
Published 2020“…Each pair resulted in a 5 Hz output following 5 Hz balanced input (as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007932#pcbi.1007932.g002" target="_blank">Fig 2</a>). …”
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146660
Temperature dramatically modulates the expression of the pigmentation gene <i>tan</i> in posterior abdominal epidermes of females.
Published 2016“…<p>(A) Cuticle pigment synthesis pathway [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006218#pgen.1006218.ref028" target="_blank">28</a>]. …”