Calcium indicator intensity in native smooth muscle stripped from day 5 rat pup. by Christopher M. Walthers (304197)

“…Regions of black indicate depolarization, while regions of white are decreases in calcium intensity as an artifact of the smooth muscle movement during contraction. 100x magnification, 200-µm scale bar. …”

<b>A Social Force Model for Companion Groups Considering Relative-Weight </b><b>Attraction</b> by yingshuang he (22678907)

Characterization of human neural progenitor cell (hNPC) derived neurons during neuronal differentiation. by Xuan Yuan (225365)

“…Representative confocal images showing the density of VGAT (vesicular GABA transporter, green) and Synapsin (red) in hNPC-derived neurons from <i>PIGA</i>wt and <i>PIGA</i>c.1234C>T cell lines. There was decreased density of VGAT and synapse formation in the hNPC-derived neurons from <i>PIGA</i>c.1234C>T cells compared to the control cell line (<i>PIGA</i>wt) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0174074#pone.0174074.s003" target="_blank">S3 Fig</a>). …”

Image_1_Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.TIF by Yao Huang (216100)

“…Conversely, after alleviating hypoxia-induced autophagic flux impairment with LC3 or ATG5 knockdown adenovirus, the effects of hypoxia on RIPK1 and RIPK3 levels were reduced, which resulted in decreased p-RIPK3 and p-MLKL. …”

Image_2_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.jpeg by Hongwei Wang (151141)

“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”

DataSheet_4_Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma.pdf by Esther C. Broner (11145870)

“…<p>Despite recent advancements, the 5 year survival of head and neck squamous cell carcinoma (HNSCC) hovers at 60%. …”

DataSheet1_Thermo-Reversible Persistent Phosphorescence Modulation Reveals the Large Contribution Made by Rigidity to the Suppression of Endothermic Intermolecular Triplet Quenchin... by Tomoya Kusama (11711552)

“…(S)-(−)-2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl ((S)-BINAP) was doped as a guest into a highly purified (S)-bis(diphenylphosphino)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl ((S)-H₈-BINAP) host. …”

Genomics of Post-Prandial Lipidomic Phenotypes in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study by Marguerite R. Irvin (102149)

“…</p><p>Methods and Results</p><p>We used gas chromatography mass spectrometry to quantify the change in plasma concentration of 35 fatty acids and 11 sterols between fasting and 3.5 hours after the consumption of a high-fat meal (PPL challenge) among 40 participants from the GOLDN study. …”

Distinct TCR repertoire in PIMS-TS/MIS-C patients: evidence for thymus involvement by Diana Yanez Marcayata (6785048)

“…We confirmed that human thymus explants can be infected with SARS-CoV-2 in vitro. …”

Image_1_Reassessing Particulate Organic Carbon Dynamics in the Highly Disturbed San Francisco Bay Estuary.TIF by Peter J. Hernes (8640351)

“…Across the ∼20-year span, we detected (1) decreasing C:N_a ratios (averages ± SD of 12.5 ± 2.5 vs. 8.8 ± 1.4, significant t-test with p < 0.0001); (2) distinct shifts in chlorophyll vs. salinity, with higher chlorophyll concentrations shifting toward freshwater; and (3) greater relative proportions of vascular plant carbon that also appears less degraded (as indicated by lignin measurements) shifting from freshwater toward higher salinities. …”

Table_2_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.xlsx by Hongwei Wang (151141)

“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”

<i>Porphyromonas gingivalis</i> Evasion of Autophagy and Intracellular Killing by Human Myeloid Dendritic Cells Involves DC-SIGN-TLR2 Crosstalk by Ahmed R. El-Awady (697683)

“…Moreover, Mfa1+<i>P. gingivalis</i> was mostly contained within single membrane vesicles, where it survived intracellularly. Survival was decreased by activation of TLR2 and/or autophagy. Mfa1+<i>P. gingivalis</i> strain did not induce significant levels of Rab5, LC3-II, and LAMP1. …”

Image_4_A Potential Mechanism of Sodium Channel Mediating the General Anesthesia Induced by Propofol.tif by Jinglei Xiao (1422004)

“…Left shift of Na_V activation around a value of 5.5 mV in the thalamocortical models suppressed normal bursting of thalamocortical (TC) cells by triggering its chaotic oscillations. …”

Image_4_Transcriptomic and Epigenomic Dynamics of Honey Bees in Response to Lethal Viral Infection.tif by Hongmei Li-Byarlay (5227208)

“…Contrasts of gene expression and 5 mC DNA methylation profiles between IAPV-infected and control individuals at these time points – corresponding to the pre-replicative (5 h), replicative (20 h), and terminal (48 h) phase of infection – indicate that profound immune responses and distinct manipulation of host molecular processes accompany the lethal progression of this virus. …”

Fenofibrate Use Is Associated With Lower Mortality and Fewer Cardiovascular Events in Patients With Diabetes: Results of 10,114 Patients From the Korean National Health Insurance S... by Sang-Ho Jo (654344)

“…<b>Objective:</b> We investigate long term clinical efficacy of fenofibrate use on mortality and cardiovascular outcomes in patients with type 2 diabetes. …”

Table_1_Outer membrane vesicles of Porphyromonas gingivalis trigger NLRP3 inflammasome and induce neuroinflammation, tau phosphorylation, and memory dysfunction in mice.xlsx by Ting Gong (195911)

“…</p>Results<p>Pg OMVs impaired memory and learning ability of mice and decreased tight junction–related gene expression ZO-1, occludin, claudin-5, and occludin protein expression in the hippocampus. …”

DataSheet_1_Depressive and anxiety symptoms, and neural correlates of reward and punishment anticipation in female athletes with amenorrhea.docx by Charumathi Baskaran (15599336)

“…</p>Results<p>Median (IQR) age and BMI of AA and EM groups were 20.6 (19.0-22.6) vs. 20.6 (19.2-23.7) years, p=0.6 and v 20.3 (18.8-21.5) vs. 21.9 (19.6-23.5) kg/m2, p=0.005, respectively. …”

Image_3_Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.TIF by Yao Huang (216100)

“…Conversely, after alleviating hypoxia-induced autophagic flux impairment with LC3 or ATG5 knockdown adenovirus, the effects of hypoxia on RIPK1 and RIPK3 levels were reduced, which resulted in decreased p-RIPK3 and p-MLKL. …”

Image_4_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.jpeg by Hongwei Wang (151141)

“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”

Image_2_Reassessing Particulate Organic Carbon Dynamics in the Highly Disturbed San Francisco Bay Estuary.TIF by Peter J. Hernes (8640351)

“…Across the ∼20-year span, we detected (1) decreasing C:N_a ratios (averages ± SD of 12.5 ± 2.5 vs. 8.8 ± 1.4, significant t-test with p < 0.0001); (2) distinct shifts in chlorophyll vs. salinity, with higher chlorophyll concentrations shifting toward freshwater; and (3) greater relative proportions of vascular plant carbon that also appears less degraded (as indicated by lignin measurements) shifting from freshwater toward higher salinities. …”