Data_Sheet_1_Integrated Metabolome and Transcriptome Analysis of Fruit Flavor and Carotenoids Biosynthesis Differences Between Mature-Green and Tree-Ripe of cv. “Golden Phoenix” Ma... by Lei Peng (260321)

“…The analysis of carotenoid contents identified 68 carotenoids and we report for the first-time significant contents of zeaxanthin palmitate and (E/Z)-phytoene in mango fruits. α-carotene was a further major contributor to carotene contents with lesser contributions from 5,6epoxy-lutein-caprate-palmitate, β-carotene, lutein oleate, and β-cryptoxanthin. …”

Image_2_Residual OXPHOS is required to drive primary and metastatic lung tumours in an orthotopic breast cancer model.tif by Patries Herst (18472197)

“…</p>Results<p>OXPHOS-deficient ATP5B-KO3.1 cells did not generate primary tumours. …”

DataSheet_1_Current Guideline Risk Stratification and Cardiovascular Outcomes in Chinese Patients Suffered From Atherosclerotic Cardiovascular Disease.docx by Sha Li (145229)

“…The survival rate was decreased by 6.2% between none- and ≥2 mASCVD events or by 3.5% between 0-1 and ≥3 high-risk conditions. …”

Table 6_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Table_1_Extracellular ATP Increases Glucose Metabolism in Skeletal Muscle Cells in a P2 Receptor Dependent Manner but Does Not Contribute to Palmitate-Induced Insulin Resistance.do... by Ana Miguel Cruz (9418637)

“…The increases in PKB and S6K1 phosphorylation were completely prevented by pre-incubation with broad spectrum purinergic receptor (P2R) blockers PPADs and suramin but not by P2 × 4 or P2 × 7 blockers 5-BDBD or A-438079, respectively. Moreover, ATPγS increased IL-6 yet decreased MIF release, similar to the cytokine profile produced by exercise. …”

Image 7_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Table 7_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Image 10_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Image_1_Significance and Determinants of Plasma Apelin in Patients With Obstructive Hypertrophic Cardiomyopathy.TIF by Chengzhi Yang (2585791)

“…</p>Results<p>Plasma apelin levels were significantly lower in patients with OHCM than those in control subjects (96.6 ± 34.3 vs. 169.4 ± 62.5 μg/L, p < 0.001). When patients with OHCM were divided into two groups according to the mean value of plasma apelin, patients with lower apelin levels (plasma apelin ≤ 96.6 μg/L) had greater septal wall thickness (SWT; 25.6 ± 5.5 vs. 23.2 ± 4.3 mm, p = 0.035) and less right ventricular end-diastolic diameter (RVEDD; 20.4 ± 3.3 vs. 23.0 ± 3.6 mm, p = 0.001). …”

Data_Sheet_1_Plasma Exosomal MiRNAs Expression Profile in Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis: Case-Control Study and Analysis of Potential Functions.ZIP by Li-Gang Huang (3405095)

“…Among them, 25 were increased and 17 decreased. After validation, hsa-miR-129-5p, -214-3p, -219a-5p, and -34c-5p were confirmed as being upregulated, while hsa-miR-421 and -184 were significantly downregulated in mTLE + HS. …”

DataSheet_1_PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome.zip by Sharmilee Vetrivel (10176326)

“…Quantitative PCR (QPCR) confirmed that PPARG (l2fc<-1.5) and related genes – FABP4 (l2fc<-5.5), PLIN1 (l2fc<-4.1) and ADIPOQ (l2fc<-3.3) – were significantly downregulated (p<0.005) in PBMAH. …”

Data_Sheet_1_Novel Compound Missense and Intronic Splicing Mutation in ALDH18A1 Causes Autosomal Recessive Spastic Paraplegia.docx by Yi-Jun Chen (444508)

“…ELISA assays revealed significantly decreased P5CS concentration in the proband's plasma compared with that in the healthy controls. …”

Data Sheet 1_The impact of environmental contaminants, air pollution, and social deprivation on childhood leukemia survival in California.docx by Fernando Hernandez (22801319)

“…</p>Results<p>124 out of 1,210 children with acute lymphoblastic leukemia (ALL) died within 5 years of diagnosis. Living in an area with a medium/high CES composite score for both pollution and population/social burdens was associated with decreased ALL survival, compared to a low CES score (HR = 2.19; 95% CI: 1.19-3.91), with population/social burden driving this observation (HR = 1.85; 95% CI: 1.06-3.21). …”

Data Sheet 1_Global assessment of terrestrial precipitation and evapotranspiration in CMIP6 simulations using observation-based estimates.docx by Shanshan Sun (275585)

“…</p>Methods<p>This study evaluates historical simulations from Phase Six of the Coupled Model Intercomparison Project (CMIP6) for precipitation (Pr), evapotranspiration (ET), and its components—soil evaporation (Es), transpiration (Et), and interception loss (Ei)—from 1981 to 2014, focusing on the temporal agreement of the mean seasonal cycle and interannual variability. We assess these variables using observation-based estimates from three Pr datasets (CRU4.0, GPCP v2.3, ERA5) and four land surface flux datasets (GLEAM v3.3a, GLDAS v2.0, ERA5-Land, MERRA-Land). …”

Evolutionary and Biotechnological Implications of Robust Hydrogenase Activity in Halophilic Strains of Tetraselmis by Sarah D'Adamo (511712)

“…The influence of salinity (3.5%, 5.5% and 7.0% w/v NaCl) on H₂ production was examined during anoxic acclimation, with the greatest in vivo H₂-production rates observed at 7.0% NaCl. …”

Image 9_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

ORCID uptake in pharma-sponsored research by Caitlin Edgell (10571574)

“…The proportion of ORCID iDs belonging to authors who are pharma employees decreased (11.5% vs 17.5% previously).</p> <p><strong>Conclusions</strong></p> <p>ORCID iD registration by pharma employees and use by authors in pharma-sponsored publications are increasing. …”

datasheet1_Air Pollution in a Low-Industry City in China’s Silk Road Economic Belt: Characteristics and Potential Sources.pdf by Fanglong Wang (10222724)

“…The results show that SO₂ and CO had a decreasing trend and NO₂, O₃, PM_2.5, and PM₁₀ had an increasing trend during the study period. …”

Data Sheet 2_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.csv by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Table_1_Cardiorespiratory fitness attenuates the association between fatness and cardiometabolic risk in Chinese children.docx by Ping-Ping Zhang (5014139)

“…Specifically, CRF mediated 6.5%, 7.7%, 5.3%, and 12.5% of the association between BMI, BMI z score, BFMI, WHtR and CMR-score (all P < 0.001). …”