Image_4_Transcriptome Analysis of Endogenous Hormone Response Mechanism in Roots of Styrax tonkinensis Under Waterlogging.TIF by Hong Chen (108084)

“…To explore endogenous hormones and phytohormone-related molecular response mechanism of S. tonkinensis under waterlogging, we determined 1-aminocyclopropane-1-carboxylic acid (ACC) and three phytohormone content (ABA, abscisic acid; SA, salicylic acid; IAA, indole-3-acetic acid) and analyzed the transcriptome of its seedlings under waterlogged condition of 3–5 cm. …”

Data_Sheet_1_Stroke care during the COVID-19 pandemic: Case numbers, treatments, and mortality in two large German stroke registries.PDF by Alicia Brunssen (13136349)

“…</p>Results<p>Hospitalization numbers decreased in the two stroke registries by 8% and 10% in Q2 of 2020 and by 5% and 15% in Q4 of 2020 compared to the same quarters in 2019, respectively. …”

Video_1_Local Delivery of Taxol From FGL-Functionalized Self-Assembling Peptide Nanofiber Scaffold Promotes Recovery After Spinal Cord Injury.MP4 by Zhiyong Xiao (2521051)

“…The local delivery of Taxol from FGLmx/Taxol significantly decreased glial scarring and increased the number of nerve fibers compared with the use of FGLmx and 5% glucose. …”

Data_Sheet_1_Local Delivery of Taxol From FGL-Functionalized Self-Assembling Peptide Nanofiber Scaffold Promotes Recovery After Spinal Cord Injury.pdf by Zhiyong Xiao (2521051)

“…The local delivery of Taxol from FGLmx/Taxol significantly decreased glial scarring and increased the number of nerve fibers compared with the use of FGLmx and 5% glucose. …”

Video_2_Local Delivery of Taxol From FGL-Functionalized Self-Assembling Peptide Nanofiber Scaffold Promotes Recovery After Spinal Cord Injury.MP4 by Zhiyong Xiao (2521051)

“…The local delivery of Taxol from FGLmx/Taxol significantly decreased glial scarring and increased the number of nerve fibers compared with the use of FGLmx and 5% glucose. …”

<i>Staphylococcus epidermidis</i> Isolated in 1965 Are More Susceptible to Triclosan than Current Isolates by Sissel Skovgaard (403044)

“…<div><p>Since its introduction to the market in the 1970s, the synthetic biocide triclosan has had widespread use in household and medical products. Although decreased triclosan susceptibility has been observed for several bacterial species, when exposed under laboratory settings, no <i>in vivo</i> studies have associated triclosan use with decreased triclosan susceptibility or cross-resistance to antibiotics. …”

Image_7_Transcriptome Analysis of Endogenous Hormone Response Mechanism in Roots of Styrax tonkinensis Under Waterlogging.TIF by Hong Chen (108084)

“…To explore endogenous hormones and phytohormone-related molecular response mechanism of S. tonkinensis under waterlogging, we determined 1-aminocyclopropane-1-carboxylic acid (ACC) and three phytohormone content (ABA, abscisic acid; SA, salicylic acid; IAA, indole-3-acetic acid) and analyzed the transcriptome of its seedlings under waterlogged condition of 3–5 cm. …”

Protein Tyrosine Phosphatase PTP1B Is Involved in Hippocampal Synapse Formation and Learning by Federico Fuentes (149005)

“…PTP1B dephosphorylates ß-catenin in N-cadherin complexes ensuring cell-cell adhesion. Here we show that endogenous PTP1B, as well as expressed GFP-PTP1B, are present in dendritic spines of hippocampal neurons in culture. …”

Video_7_Local Delivery of Taxol From FGL-Functionalized Self-Assembling Peptide Nanofiber Scaffold Promotes Recovery After Spinal Cord Injury.MP4 by Zhiyong Xiao (2521051)

“…The local delivery of Taxol from FGLmx/Taxol significantly decreased glial scarring and increased the number of nerve fibers compared with the use of FGLmx and 5% glucose. …”

R code containing functions for data analysis from An evolutionary model to predict the frequency of antibiotic resistance under seasonal antibiotic use, and an application to <i>S... by François Blanquart (3191950)

“…One extra monthly prescription of cephalosporins per 1000 children decreased the frequency of penicillin-resistant strains by 1.7%. …”

Supplementary Material for: Protective Effects of Vitamin E on Chemotherapy-Induced Peripheral Neuropathy: A Meta-Analysis of Randomized Controlled Trials by Miao H. (10991571)

“…Moreover, vitamin E supplementation significantly decreased patients’ sural amplitude after 3 rounds of chemotherapy (RR −2.66; 95% CI −5.09 to −0.24; <i>p</i> = 0.03) in contrast with that of placebo supplementation, while no significant difference was observed when patients were treated with vitamin E after 6 rounds of chemotherapy. …”

Table_2_Age-Dependent Changes in Transcription Factor FOXO Targeting in Female Drosophila.pdf by Allison Birnbaum (6669461)

“…Although the transcriptional regulation of FOXO have been previously characterized (especially in long-lived insulin mutants and under stress conditions), how normal aging impacts the transcriptional activity of FOXO is poorly understood. Here, we conducted a chromatin immunoprecipitation sequencing (ChIP-Seq) analysis in both young (2-week-old) and aged (5-week-old) wild-type female fruit flies, Drosophila melanogaster, to evaluate the dynamics of FOXO gene targeting during aging. …”

Table_1_Lacticaseibacillus rhamnosus Hao9 exerts antidiabetic effects by regulating gut microbiome, glucagon metabolism, and insulin levels in type 2 diabetic mice.XLSX by Mei Han (127139)

“…The composition of the gut microbiome was modulated by Hao9, with an increased abundance of Roseburia, Eubacterium, and Lacticaseibacillus, and decreased abundance of Escherichia/Shigella. Notably, Lacticaseibacillus was detected at both weeks 5 and 12 post-treatment, suggesting sustained colonization of the gut by Hao9.…”

A Structural Mechanism for Calcium Transporter Headpiece Closure by Nikolai Smolin (1371696)

“…We quantified differences in structural disorder and dynamics for an open conformation of SERCA versus closed structures and observed that dynamic motions of SERCA cytoplasmic domains decreased with decreasing domain–domain separation distance. …”

Image_10_Canonical and Non-canonical TGFβ Signaling Activate Autophagy in an ULK1-Dependent Manner.TIF by Charles B. Trelford (11601802)

“…We demonstrated that TGFβ1 increases Unc 51-like kinase 1 (ULK1) protein levels, 5′ adenosine monophosphate-activated protein kinase (AMPK)-dependent ULK1 phosphorylation at serine (S) 555 and ULK1 complex formation but decreases mechanistic target of rapamycin (mTOR) activity on ULK1. …”

Image_2_Neuroimmune pathways involvement in neurodegeneration of R6/2 mouse model of Huntington’s disease.tif by Emanuela Paldino (499905)

“…Such activity is mediated by the inhibition (dephosphorylation) of the proteins signal transducer and activator of transcription (STAT). We found that activated SHP-1 was present in microglia and neurons of WT mice at 5 and 13 weeks, increasing with time; while in R6/2 it was not localized in neurons but only in microglia, where it decreases with time. …”

Trends of cause-specific cardiovascular disease mortality in China, 2009-2019: a nationwide longitudinal study by Lu Wang (45927)

“…The CMR of all CVD increased [the annual average percentage change (AAPC) = 3.4%, 95% confidence interval (CI) 2.6% to 4.1%] while the ASMR decreased (AAPC = −2.0%, 95% CI −3.5% to −0.6%). Cerebrovascular disease is predicted to be the leading cause of CVD death in men and IHD will be the top cause of CVD death in women over the period 2025-2029.…”

Image_7_Canonical and Non-canonical TGFβ Signaling Activate Autophagy in an ULK1-Dependent Manner.TIF by Charles B. Trelford (11601802)

“…We demonstrated that TGFβ1 increases Unc 51-like kinase 1 (ULK1) protein levels, 5′ adenosine monophosphate-activated protein kinase (AMPK)-dependent ULK1 phosphorylation at serine (S) 555 and ULK1 complex formation but decreases mechanistic target of rapamycin (mTOR) activity on ULK1. …”

Supplementary Material for: Cancer associated fibroblasts induce proliferation and therapeutic resistance to everolimus in neuroendocrine tumors through STAT3 activation by Amin T. (14226773)

“…STAT3 activation in NET tissue was associated with de-creased chromogranin A expression, increased Ki-67 index and decreased 5-year overall and progression free survival. …”

Image_1_Saccharomyces Boulardii Ameliorates Non-alcoholic Steatohepatitis in Mice Induced by a Methionine-Choline-Deficient Diet Through Gut-Liver Axis.TIF by An-Ming Yang (12436298)

“…For this study, we fed eight-week-old C57/BL6 male mice either a methionine-choline deficient (MCD) diet or a normal chow diet (NCD) for eight weeks. …”