Cholinergic Modulation of Narcoleptic Attacks in Double Orexin Receptor Knockout Mice by Mike Kalogiannis (224818)

“…The muscarinic antagonist atropine (0.5 mg/kg, IP) decreased the number of arrests, also without altering arrest lifetimes. …”

DataSheet_1_Circulating microRNA responses to acute whole-body vibration and resistance exercise in postmenopausal women.docx by Samuel R. Buchanan (12253793)

“…There was a significant modality × time interaction for c-miR-21-5p expression (p=0.019), which decreased from 60P to 24H after WBV only. …”

Data_Sheet_1_miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients.PDF by Diana J. Cha (8041226)

“…ROC analysis indicated that measurement of miR-132-3p in neurally-derived plasma EVs showed good sensitivity and specificity to diagnose AD, but did not effectively separate individuals with AD-MCI from controls. Moreover, when we measured the levels of a related miRNA, miR-212, we found that this miRNA was also decreased in neural EVs from AD patients compared to controls. …”

Figure CSA-2 4.15 by CIMR project (7352015)

Image_1_Significance and Determinants of Plasma Apelin in Patients With Obstructive Hypertrophic Cardiomyopathy.TIF by Chengzhi Yang (2585791)

“…</p>Results<p>Plasma apelin levels were significantly lower in patients with OHCM than those in control subjects (96.6 ± 34.3 vs. 169.4 ± 62.5 μg/L, p < 0.001). When patients with OHCM were divided into two groups according to the mean value of plasma apelin, patients with lower apelin levels (plasma apelin ≤ 96.6 μg/L) had greater septal wall thickness (SWT; 25.6 ± 5.5 vs. 23.2 ± 4.3 mm, p = 0.035) and less right ventricular end-diastolic diameter (RVEDD; 20.4 ± 3.3 vs. 23.0 ± 3.6 mm, p = 0.001). …”

Table_1_Significance and Determinants of Plasma Apelin in Patients With Obstructive Hypertrophic Cardiomyopathy.DOCX by Chengzhi Yang (2585791)

“…</p>Results<p>Plasma apelin levels were significantly lower in patients with OHCM than those in control subjects (96.6 ± 34.3 vs. 169.4 ± 62.5 μg/L, p < 0.001). When patients with OHCM were divided into two groups according to the mean value of plasma apelin, patients with lower apelin levels (plasma apelin ≤ 96.6 μg/L) had greater septal wall thickness (SWT; 25.6 ± 5.5 vs. 23.2 ± 4.3 mm, p = 0.035) and less right ventricular end-diastolic diameter (RVEDD; 20.4 ± 3.3 vs. 23.0 ± 3.6 mm, p = 0.001). …”

Pace Versus Prediction: Is the Experience of the Runner Associated With Marathon Success? by Dan Gordon (2110918)

“…Significant differences observed between PT and FT for all EXP groups apart from EXP-5 (P= 0.0001). EXP-0 showed significant difference across all split times apart from 35-40 km (P=0.0001) with a decrease in normalised speed from 5km (109.0 ±7.6) –40km (89.9 ±7.4%). …”

All-atom molecular dynamics simulation of peptides by Ning Zhu (10901010)

MPA gap analysis results based upon alternate choices of datasets. by Casey C. O'Hara (3997529)

“…Scenario 2 updates the results using AquaMaps version 08/2015, showing very small changes despite the inclusion of an additional 5,545 species. Scenario 3, still using 2015 AquaMaps data, drops the presence threshold to zero, showing an expected decrease in gap species, but also a decrease in species with 5% or greater protected range. …”

Example simulation of the 2D Ising model. by Manfred Füllsack (4691716)

“…<p>Simulation of the 2D-Ising model with an external magnetic field H taken as critical parameter (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0259177#pone.0259177.e001" target="_blank">Eq 1</a>), on the x-axis, first increasing (H = -0.5 to 0.6, left half) and then decreasing (H = 0.6 to -0.5, right half). …”

Development of an <i>in vitro</i> media perfusion model of <i>Leishmania major</i> macrophage infection by Alec O’Keeffe (7037294)

“…Media perfusion also decreased amastigote replication and both macrophage phagocytosis (by 44±4% under slow flow and 57±5% under fast flow compared with the static condition) and macropinocytosis (by 40±4% under slow flow and 62±5% under fast flow compared with the static condition) as measured by uptake of latex beads and pHrodo Red dextran.…”

Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia by April C.E. van Gennip (10993229)

“…</p> <p><b>Results </b>After a mean follow-up of 9.0 years, 147(1.4%) individuals with diabetes and 412(0.5%) controls had incident dementia. …”

12-HETE induces phosphorylation of VEGF-R2 and dephosphorylation of protein tyrosine phosphatase (PTP) SHP1 in REC. by Amira Othman (380131)

“…<p>Western blotting analysis (A) demonstrated significant increase in the level of pVEGF-R2 after 5 and 60 minutes from the beginning of treatment with 12-HETE. …”

Stronger evidentiary standards do not reduce the need to publish negative outcomes by Silas Boye Nissen (6815351)

“…Figure 6 Strengthening evidentiary requirements does not necessarily decrease canonization of false facts. In panel A, the false positive rate is α=0.05, the false negative rate is β=0.2, the original belief in the claim is q_0=0.5, and the evidentiary standards are symmetric τ_1=1-τ_0. …”

Halo assay performed in MCF7 cells. by Siddharth Manvati (391250)

“…<p>(a) NDF-nuclear diffusion factor-values showing the extent of DNA damage with increasing concentrations of etoposide (p Value <0.001), (b) Percentage of senescent cell population (using β-gal assay) and Annexin-V positive-apoptotic-cell population (through FACS analysis): showing decrease in senescence and increase in Apoptosis (*p Value <0.05), (c) miR-101 expression (using Real-Time PCR): showing decrease with increasing concentration of etoposide (1 µM, 5 µM and 10 µM) for 12 hrs (**p Value <0.005).…”

Table_1_Gestational Low Protein Diet Modulation on miRNA Transcriptome and Its Target During Fetal and Breastfeeding Nephrogenesis.XLSX by Letícia de Barros Sene (447783)

“…The miRNA 181c-3p modulated SIX2 and Notch1 reduction in 7-DL but not in terms of the enhanced expression of both in the 21-GD, suggesting the participation of an additional regulator. We found enhanced Bax in 21-GD; it was regulated by miRNA 298-5p, and Bcl2 and Caspase-3 were controlled by miRNA (by 7a-5p and not by the predicted 181a-5p). …”

Simultaneous measurements of cytosolic and mitochondrial Mg²⁺ concentration changes. by Yutaka Shindo (209437)

“…Administration of 5 µM FCCP induced a rapid increase in [Mg²⁺]_cyto and a gradual decrease in [Mg²⁺]_mito. …”

Measurements of time in acupuncture manipulation techniques. by In-Seon Lee (483585)

“…<p>(a) Rotation; (+): Thumb forward (TF); (-): Thumb backward (TB); TF time error = |0.5 s—TF time|, mean ± SE; TB time error = |0.5 s—TB time|, mean ± SE; Target ratio of time = TF time/TB time = 1:1. …”

Table_4_RNA-Seq and 16S rRNA Analysis Revealed the Effect of Deltamethrin on Channel Catfish in the Early Stage of Acute Exposure.xlsx by Yibin Yang (262311)

“…However, the toxicological mechanisms of Del on channel catfish remain unclear. In the present study, we exposed channel catfish to 0, 0.5, and 5 μg/L Del for 6 h, and analyzed the changes in histopathology, trunk kidney transcriptome, and intestinal microbiota composition. …”

Table_9_RNA-Seq and 16S rRNA Analysis Revealed the Effect of Deltamethrin on Channel Catfish in the Early Stage of Acute Exposure.xls by Yibin Yang (262311)

“…However, the toxicological mechanisms of Del on channel catfish remain unclear. In the present study, we exposed channel catfish to 0, 0.5, and 5 μg/L Del for 6 h, and analyzed the changes in histopathology, trunk kidney transcriptome, and intestinal microbiota composition. …”