Image_3_Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.jpeg by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

Image_1_RETRACTED: Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy.JPEG by Jia Zheng (140297)

“…Opa1 overexpression reversed this effect by increasing endothelial cell viability and decreasing apoptosis. Interestingly, inhibition of mitophagy or mitochondrial fusion through transfection of siRNAs against Atg5 or Mfn2, respectively, abolished the protective effects of Opa1. …”

DataSheet_1_Strategies for Accurate Cell Type Identification in CODEX Multiplexed Imaging Data.pdf by John W. Hickey (4497922)

“…First, increasing cell-type granularity led to decreased labeling accuracy; therefore, subtle phenotype annotations should be avoided at the clustering step. …”

Table_1_Strategies for Accurate Cell Type Identification in CODEX Multiplexed Imaging Data.xlsx by John W. Hickey (4497922)

“…First, increasing cell-type granularity led to decreased labeling accuracy; therefore, subtle phenotype annotations should be avoided at the clustering step. …”

Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport by Shanthie Thamotharan (3992894)

“…In a larger cohort of samples (AGA, n = 21; SGA, n = 11; IUGR subset, n = 5), we validated by qRT-PCR differential expression of three specific microRNAs (<i>miR-10b</i>, <i>-363 and -149</i>) that target genes mediating angiogenesis and nutrient transfer. …”

The Rab11 Effector Protein FIP1 Regulates Adiponectin Trafficking and Secretion by Brian P. Carson (187501)

“…Furthermore shRNA-mediated depletion of FIP1 enhanced adiponectin release whereas knock down of FIP5 decreased adiponectin secretion. Knock down of FIP3 had no effect. …”

Metabolic and hemodynamic evaluation of two long term sedation protocols in dogs by D. Regalin (8143476)

“…CaO2, CmvO2, DO2 and VO2 decreased in GCM (5%, 16%, 31% and 7% respectively) and GMF (4%, 19%, 26% and 15% respectively). …”

Image_3_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_4_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIFF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_3_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

DataSheet_1_Clinical evaluation of bacterial DNA using an improved droplet digital PCR for spontaneous bacterial peritonitis diagnosis.docx by Hao-Xin Wu (13263747)

“…</p>Results<p>After the removal of free DNA, the bactDNA detected by ddPCR was generally decreased (1.75 vs. 1.5 log copies/µl, P < 0.001). …”

High-resolution SEM analysis of tip links. by Kateri J. Spinelli (293686)

“…(e, f) Bundles treated with 5 mM EGTA for 5 min showed a marked decrease in bundle Fluo-4 fluorescence and a significant reduction in the number of tip links (g, h). …”

Diffusive dynamics of white player’s advantage. by Haroldo V. Ribeiro (277883)

The <i>I</i>_K1/Kir2.1 channel agonist zacopride prevents and cures acute ischemic arrhythmias in the rat by Xu-Wen Zhai (4033601)

“…However, clinical anti-arrhythmic agents that primarily act on RMP by enhancing the <i>I</i>_K1 channel are not currently available. We hypothesized that zacopride, a selective and moderate agonist of the <i>I</i>_K1/Kir2.1 channels, prevents and cures acute ischemic arrhythmias. …”

Properties of the optimal force selection model. by Nicolas Borderies (9510718)

“…<b>C2</b>: increase of K_e (sensitivity to effort) leads to decrease of optimal value and decrease of optimal force with a collapse to zero-force when the optimal value becomes negative. …”

Reproductive phenology and germination of Eleocharis laeviglumis R. Trevis. & Boldrini (Cyperaceae) by Camila Luisa Bernhardt Demeda (5765687)

“…We also tested seed germinability and vigor for a period of four months during a single reproductive season. …”