MicroRNA and cellular targets profiling reveal miR-217 and miR-576-3p as proviral factors during Oropouche infection by Victor Emmanuel Viana Geddes (5309945)

“…Finally, we showed that virus escape IFN-β mediated immune response increasing the levels of cellular miR-576-3p resulting in a decreasing of its partners STING and TRAF3. …”

DataSheet_1_Nitric oxide-induced lipophagic defects contribute to testosterone deficiency in rats with spinal cord injury.docx by Yuge Zhuang (18008935)

“…Alternatively, activated (M1) macrophages were predominant NO sources, as inducible NO synthase inhibition attenuated lipophagic defects and testosterone insufficiency in LCs in a macrophage-LC co-culture system. In scavenging NO (2-4-carboxyphenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (CPTIO)) we effectively restored lipophagy and testosterone levels both in vitro and in vivo, and importantly, spermatogenesis in vivo. …”

Image_2_Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis.tiff by Chieh-Yu Liao (6100055)

“…Immune cell-driven inflammation is a key determinant of NASH progression. Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire of 5 receptors termed S1P₁ – S1P₅. …”

Image_6_Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis.tiff by Chieh-Yu Liao (6100055)

“…Immune cell-driven inflammation is a key determinant of NASH progression. Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire of 5 receptors termed S1P₁ – S1P₅. …”

Image_3_Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis.tiff by Chieh-Yu Liao (6100055)

“…Immune cell-driven inflammation is a key determinant of NASH progression. Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire of 5 receptors termed S1P₁ – S1P₅. …”

Image_7_Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis.tiff by Chieh-Yu Liao (6100055)

“…Immune cell-driven inflammation is a key determinant of NASH progression. Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire of 5 receptors termed S1P₁ – S1P₅. …”

Image_1_Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis.tiff by Chieh-Yu Liao (6100055)

“…Immune cell-driven inflammation is a key determinant of NASH progression. Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire of 5 receptors termed S1P₁ – S1P₅. …”

Image_4_Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis.tiff by Chieh-Yu Liao (6100055)

“…Immune cell-driven inflammation is a key determinant of NASH progression. Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire of 5 receptors termed S1P₁ – S1P₅. …”

Acute Hyperglycemia Increases Brain Pregenual Anterior Cingulate Cortex Glutamate Concentrations in Type 1 Diabetes Mellitus by Ada Admin (8524211)

“…Using proton magnetic resonance spectroscopy (MRS), we measured glutamate concentrations in ACC and occipital cortex (OCC) in 13 T1D without major depression (HbA1c=7.1±0.7% [54±7mmol/mol]) and 11 healthy non-diabetic controls (HbA1c=5.5±0.2% [37±3mmol/mol]) during fasting euglycemia (EU) followed by a 60-minute +5.5mmol/l hyperglycemic clamp (HG). …”

Supplemental Figure 1 by Lipschutz (18506103)

“…For B,C red denotes an increase and green a decrease in levels. Statistical results for p<0.05 and for 0.05 are shown.…”

Male-biased effects of ubiquitous RNAi-mediated <i>bmm</i> inhibition reduces sex differences in triglyceride storage and breakdown. by Lianna W. Wat (8339454)

“…(K) Between 0 and 12 hours STV, triglyceride breakdown in <i>da>UAS-bmm-RNAi#2</i> (BDSC #25926) females was blocked, whereas triglyceride levels decreased in <i>da>+</i> and <i>+>UAS-bmm-RNAi#2</i> control females (<i>p</i> = 0.18, 0.036, and 9.9 × 10⁻⁵, respectively; one-way ANOVA followed by Tukey HSD test), whereas we observed similar magnitudes of triglyceride breakdown between 12 and 24 hours STV in <i>da>+</i>, <i>+>UAS-bmm-RNAi#2</i>, and <i>da>UAS-bmm-RNAi#2</i> (BDSC #25926) females (<i>p</i> = 0.032, 0.28, and 0.022, respectively; one-way ANOVA followed by Tukey HSD test). …”

Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model by Da'as, Sahar I.

“…MYBPC3 variants genotype–phenotype associations remain poorly understood. We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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Data_Sheet_1_Cell Wall Proteomics Reveal Phenotypic Adaption of Drug-Resistant Mycobacterium smegmatis to Subinhibitory Rifampicin Exposure.XLSX by Alexander D. Giddey (11522167)

“…We verified the drug resistance status of this strain and observed no phenotypic indications of rifampicin-induced stress upon treatment with the same concentration as used in WT (2.5 μg/ml). …”

Table_2_Gut Microbial Profile Is Associated With Residential Settings and Not Nutritional Status in Adults in Karnataka, India.xlsx by Ojasvi Mehta (10180544)

“…Nutritional status was assessed based on BMI, with a BMI of < 18.5 kg/m² classified as undernourished, and a BMI in the range 18.5–25 kg/m² as nourished. …”

Image_2_Gut Microbial Profile Is Associated With Residential Settings and Not Nutritional Status in Adults in Karnataka, India.jpg by Ojasvi Mehta (10180544)

“…Nutritional status was assessed based on BMI, with a BMI of < 18.5 kg/m² classified as undernourished, and a BMI in the range 18.5–25 kg/m² as nourished. …”

Image_1_Gut Microbial Profile Is Associated With Residential Settings and Not Nutritional Status in Adults in Karnataka, India.jpg by Ojasvi Mehta (10180544)

“…Nutritional status was assessed based on BMI, with a BMI of < 18.5 kg/m² classified as undernourished, and a BMI in the range 18.5–25 kg/m² as nourished. …”

Table_1_Gut Microbial Profile Is Associated With Residential Settings and Not Nutritional Status in Adults in Karnataka, India.xlsx by Ojasvi Mehta (10180544)

“…Nutritional status was assessed based on BMI, with a BMI of < 18.5 kg/m² classified as undernourished, and a BMI in the range 18.5–25 kg/m² as nourished. …”

Data_Sheet_2_Cell Wall Proteomics Reveal Phenotypic Adaption of Drug-Resistant Mycobacterium smegmatis to Subinhibitory Rifampicin Exposure.docx by Alexander D. Giddey (11522167)

“…We verified the drug resistance status of this strain and observed no phenotypic indications of rifampicin-induced stress upon treatment with the same concentration as used in WT (2.5 μg/ml). …”

Table_1_Association between organophosphate flame retardant exposure and lipid metabolism: data from the 2013–2014 National Health and Nutrition Examination Survey.docx by Fu-Jen Cheng (9992941)

“…With increasing quartiles of urine BDCPP levels, the mean TC levels significantly decreased in all participants (p value for trend = 0.028), and quartile increases in the levels of DPhP (p value for trend = 0.01), BDCPP (p value for trend = 0.001), and BCEP (p value for trend<0.001) were negatively corelated with HDL-C, with approximately 5.9, 9.9, and 12.5% differences between the upper and lower quartiles. …”

Behavioral classification and scan of parameter space. by Zoe Nahas (22250651)

“…Here, colors are assigned based on the theoretically possible behaviors, as determined by the number and values of stable steady states. In <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003395#pbio.3003395.g004" target="_blank">Figs 4</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003395#pbio.3003395.s003" target="_blank">S3</a>, colors are assigned based on the bud growth outcomes that were obtained after running 100 stochastic simulations for 120 time steps, for each combination of (<i>v0</i>, <i>µ</i>) values. …”