Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Knockdown of Tsg101 and Alix decrease the production of infectious OROV. by Natalia S. Barbosa (5172338)

Parrotfish Teeth: Stiff Biominerals Whose Microstructure Makes Them Tough and Abrasion-Resistant To Bite Stony Corals by Matthew A. Marcus (115744)

“…Its enameloid is a fluorapatite (Ca₅(PO₄)₃F) biomineral with outstanding mechanical characteristics: the mean elastic modulus is 124 GPa, and the mean hardness near the biting surface is 7.3 GPa, making this one of the stiffest and hardest biominerals measured; the mean indentation yield strength is above 6 GPa, and the mean fracture toughness is ∼2.5 MPa·m^1/2, relatively high for a highly mineralized material. …”

Parrotfish Teeth: Stiff Biominerals Whose Microstructure Makes Them Tough and Abrasion-Resistant To Bite Stony Corals by Matthew A. Marcus (115744)

“…Its enameloid is a fluorapatite (Ca₅(PO₄)₃F) biomineral with outstanding mechanical characteristics: the mean elastic modulus is 124 GPa, and the mean hardness near the biting surface is 7.3 GPa, making this one of the stiffest and hardest biominerals measured; the mean indentation yield strength is above 6 GPa, and the mean fracture toughness is ∼2.5 MPa·m^1/2, relatively high for a highly mineralized material. …”

Parrotfish Teeth: Stiff Biominerals Whose Microstructure Makes Them Tough and Abrasion-Resistant To Bite Stony Corals by Matthew A. Marcus (115744)

“…Its enameloid is a fluorapatite (Ca₅(PO₄)₃F) biomineral with outstanding mechanical characteristics: the mean elastic modulus is 124 GPa, and the mean hardness near the biting surface is 7.3 GPa, making this one of the stiffest and hardest biominerals measured; the mean indentation yield strength is above 6 GPa, and the mean fracture toughness is ∼2.5 MPa·m^1/2, relatively high for a highly mineralized material. …”

Parrotfish Teeth: Stiff Biominerals Whose Microstructure Makes Them Tough and Abrasion-Resistant To Bite Stony Corals by Matthew A. Marcus (115744)

“…Its enameloid is a fluorapatite (Ca₅(PO₄)₃F) biomineral with outstanding mechanical characteristics: the mean elastic modulus is 124 GPa, and the mean hardness near the biting surface is 7.3 GPa, making this one of the stiffest and hardest biominerals measured; the mean indentation yield strength is above 6 GPa, and the mean fracture toughness is ∼2.5 MPa·m^1/2, relatively high for a highly mineralized material. …”

Decrease in splenic lymphoid chemokines in mice developing Amela-melanomas. by Saïdi M. Soudja (118745)

MML-induced autophagy is associated with the decrease in p53 levels. by Hyun-Kyu An (498473)

Increasing cell density beyond a threshold decreases both cell survival and VEGF secretion. by Rachel Coy (4027016)

Su(H) and RBPJ AOS variants decrease DNA binding. by Ellen K. Gagliani (11478756)

Decrease of mitochondrial protein levels in human OPMD muscle biopsies. by Aymeric Chartier (713911)

JNK inhibitor AS601245 significantly rescued the decrease in p-FOXO3a and attenuated FOXO3a translocation into nucleus after HI with no influence on p-Akt. by Deyuan Li (769599)

Search duration decreases with target value and increases with the environment’s probability of containing a reward target. by Michael R. Traner (11836571)

Telmisartan decreased NO production in LPS-stimulated BV2 and primary neonatal rat glial cells. by Nofar Torika (3169497)

AMS scores decrease over three days at high-altitude. by Erica C. Heinrich (6832055)

Loss of nsp14-ExoN activity decreases recombination frequency and alters recombination junction patterns across the genome. by Jennifer Gribble (10005444)

NEMO knockout murine dermal fibroblasts show a decreased nuclear translocation of p65. by Patrick Meyer (3395285)

Decrease of GFP-TbAtg8 fluorescence during starvation. by Remo S. Schmidt (546946)

Decreased reductase activity and increased round body formation in the <i>gpsA</i> mutant. by Dan Drecktrah (36180)