TGM2 inhibition by siRNA treatment induces cell apoptosis. by Yin-Cheng Huang (633119)

“…Meningioma cells treated with <i>TGM2</i> siRNA exhibited reduced TGM2 expression in a dose-dependent manner (>80% in 5 nM siRNA). (B) Cell viability assessed using the MTT assay showed 30% decrease of cell survival following 5 nM siRNA exposure. …”

Lpp supplies lipids to peripheral organs. by Wilhelm Palm (148641)

“…<p>(A–D) Changes in wing disc neutral lipids upon LTP or Lpp RNAi, quantified by mass spectrometry (n = 5). …”

GA did not induce neuronal death in absence of astrocytes. by Silvia Olivera-Bravo (349736)

“…<p>Isolated striatal neuronal cultures were employed to investigate the mechanism of GA-induced neurotoxicity. <b>A:</b> Phase contrast of E18 striatal neurons at 5 DIV exposed to vehicle or 5 mM GA (pH 7.4, 24 h). …”

MMP-2, MMP-9, TIMP-3 expression and collagenolytic activity in the failing heart. by Federica Limana (216501)

“…(E) TIMP-3 protein levels were lower in failing hearts, both in the border zone and in the infarcted area, than in SO hearts. HMGB1 caused a further decrease in TIMP-3 protein. Both for MMPs (C) and TIMP-3, the same filter was probed with α-tubulin to normalize protein loading (n = 5 for the average results of densitometric analyses of western blots).…”

Specificity of HUVECs intoxication by C2I using PA₆₃ in comparison to C2II. by Angelika Kronhardt (304086)

“…<p>HUVECs (5×10⁵ cells/100 mm well) were intoxicated with the indicated concentration of polypeptides during 48 (A) or 24 hours (B). …”

IL-2-activated NK cells from patients exhibited antitumor capacities. by Giulia Fregni (349403)

“…NK cells (ratio 2/1) induce a rapid decrease of adherent target cell index (dotted line: 120 min after NK addition). …”

Transmission kernels. by Elisa Benincà (120328)

“…Parameter values are based on estimates by Boender et al. [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008009#pcbi.1008009.ref005" target="_blank">5</a>] for the Dutch epidemic of avian influenza in 2003, but with rescaling to account for the decrease in number of farms (from 5,360 to 2,157) and concomitant increase in size of farms since 2003.…”

<i>Helicobacter pylori</i> antibody and pepsinogen testing for predicting gastric microbiome abundance by Saemi Choi (8082164)

“…<div><p>Background</p><p>Although the high-throughput sequencing technique is useful for evaluating gastric microbiome, it is difficult to use clinically. We aimed to develop a predictive model for gastric microbiome based on serologic testing.…”

Effect of RF center overlap on correlations in the three parallel ELL segments. by Volker Hofmann (3326613)

“…<p><b>(A)</b> We modeled differences in RF center size and overlap by varying the number of afferents converging onto pyramidal cells (LS: blue; CLS: magenta; CMS: green). …”

Video_2_Recovery from cold-induced mitochondrial fission in endothelial cells requires reconditioning temperatures of ≥ 25◦C.WMV by Leonard Quiring (14048349)

“…However, it is unclear whether other temperatures as currently discussed for reconditioning of organs allow this reconstitution of mitochondria. Therefore, we here study in a model of cultured porcine aortic endothelial cells how different rewarming temperatures affect mitochondrial re-fusion and function. …”

Video_1_Recovery from cold-induced mitochondrial fission in endothelial cells requires reconditioning temperatures of ≥ 25◦C.WMV by Leonard Quiring (14048349)

“…However, it is unclear whether other temperatures as currently discussed for reconditioning of organs allow this reconstitution of mitochondria. Therefore, we here study in a model of cultured porcine aortic endothelial cells how different rewarming temperatures affect mitochondrial re-fusion and function. …”

The associations between H3K9me3 density of genes and their neighborhood TE content. by Yuh Chwen G. Lee (156484)

“…The H3K9me3 density of genes that have at least one TE in the introns of the gene (in gene), within 1kb, 1-2kb, 2-5kb, and 5-10kb upstream/downstream from the gene are significantly lower than those of genes that have no TE 10kb upstream/downstream (whose median of H3K9me3 density is shown as a dashed line). …”

(S)-2 induced growth arrest in LNCAP cells. by Anna Laurenzana (296271)

“…(<b>B</b>, middle) – Phase contrast pictures of companion cultures indicated that (S)-2 induced morphological changes and a marked decrease in cell density. (<b>B</b>, bottom) – Cells were treated with 2.5 µM drug for the indicated time points and p21 protein levels were monitored by immunoblotting; GAPDH was also examined to ensure equal loading of samples in each lane. …”

DataSheet1_Functional characterization of SGLT1 using SSM-based electrophysiology: Kinetics of sugar binding and translocation.pdf by Andre Bazzone (3169068)

“…From the steady-state transport current, we found a sequence for sugar specificity (V_max/K_M): D-glucose > MDG > D-galactose > 3-OMG > D-xylose. …”

DataSheet1_Cardiac stroke volume in females and its correlation to blood volume and cardiac dimensions.DOCX by Janis Schierbauer (13866371)

“…The hemoglobin concentration [Hb] increased by 0.8 ± 0.3 g·dL⁻¹, the capillary oxygen saturation (ScO₂) decreased by 4.0% (p < 0.001). As a result, the calculated arterial oxygen content significantly increased (18.5 ± 1.0 vs. 18.9 ± 1.0 mL·dL⁻¹, p = 0.001). …”

Table_1_Correlation analysis between 18F-fluorodeoxyglucose positron emission tomography and cognitive function in first diagnosed Parkinson’s disease patients.docx by Sun Zhihui (16320159)

“…Further regression analysis showed that for every one-point decrease in the memory score, the glucose metabolism in the right precuneus would decrease by 0.3 (B = 0.30, p = 0.005), the glucose metabolism in the left primary visual cortex would decrease by 0.25 (B = 0.25, p = 0.040), the glucose metabolism in the right lateral occipital cortex would decrease by 0.38 (B = 0.38, p = 0.012), and the glucose metabolism in the left lateral occipital cortex would decrease by 0.32 (B = 0.32, p = 0.045).…”

Table_2_Correlation analysis between 18F-fluorodeoxyglucose positron emission tomography and cognitive function in first diagnosed Parkinson’s disease patients.docx by Sun Zhihui (16320159)

“…Further regression analysis showed that for every one-point decrease in the memory score, the glucose metabolism in the right precuneus would decrease by 0.3 (B = 0.30, p = 0.005), the glucose metabolism in the left primary visual cortex would decrease by 0.25 (B = 0.25, p = 0.040), the glucose metabolism in the right lateral occipital cortex would decrease by 0.38 (B = 0.38, p = 0.012), and the glucose metabolism in the left lateral occipital cortex would decrease by 0.32 (B = 0.32, p = 0.045).…”

The Difference in Prognostic Factors between Early Recurrence and Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Nodal Stage Differently Impacts Early and Late Recurr... by Sung Gwe Ahn (414680)

“…</p><p>Methods</p><p>Five hundred and ninety five patients diagnosed with ER-positive breast cancer between 1989 and 2001 were classified into three groups: early recurrence within 5 years, late recurrence after 5 years, and no recurrence. …”

NDGA blocks calcium-induced increase of the <i>PADI</i>3 mRNA levels and impairs c-Jun or c-Fos recruitment at PIE. by Stéphane Chavanas (270094)

“…In NHEKs treated with NDGA, calcium stimulation associated with only a 1.5 fold increase in involucrin mRNA levels. …”

DataSheet1_Electrokinetic properties of healthy and β-thalassemia erythrocyte membranes under in vitro exposure to static magnetic field.pdf by Virjinia Doltchinkova (17203663)

“…</p><p>Results: The electrokinetic potential of erythrocytes in norm is increased after SMF intensities due to enhanced negatively exposed charges on the outer surface of the membrane accompanied by an increase in light scattering where changes in cell morphology are observed. Conversely, a decrease in the zeta potential of β-thalassemia erythrocytes upon SMF-treatment was determined because of the reduction in the surface electrical charge of the membranes, where a significant decrease in light scattering at 1.5 T and 2.0 T was recorded. …”