Table 2_Global burden trends of tension-type headache, 1990–2021: socio-demographic patterns, age-period-cohort effects, and frontier analysis from the GBD 2021 study.docx by Can Wang (157994)

“…APC analysis revealed global peak prevalence at age 32.5 years, with period effects showing decreases in High SDI regions but increases in Middle SDI regions. …”

Pneumococcal RNase R globally impacts protein synthesis by regulating the amount of actively translating ribosomes by Cátia Bárria (6174782)

“…We present evidences showing that accumulation of these factors leads to a decreased amount of 70S active particles, as demonstrated by the altered sucrose gradient ribosomal pattern in the RNase R mutant strain. …”

The impact of haulroad geometric parameters on open pit mine strip ratio by Douglas Alexandre Gonçalves Alegre (6302681)

Phenotypic shift of the Type B CPC populations. by Jussi V. Leinonen (388249)

Clinical outcomes (MACE). by Tomohiko Shindo (612852)

“…The average weekly nitroglycerin use (times/week) was decreased from 5.50 to 2.44 in the LIPUS group and from 5.94 to 2.83 in the placebo group. …”

Baseline patient characteristics. by Tomohiko Shindo (612852)

“…The average weekly nitroglycerin use (times/week) was decreased from 5.50 to 2.44 in the LIPUS group and from 5.94 to 2.83 in the placebo group. …”

Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway by Komal Qureshi-Baig (844550)

“…Genetic targeting of autophagy or pharmacological inhibition of PRKC/PKC and EZR resulted in decreased tumor-initiating potential of TICs. In addition, we observed significantly reduced <i>in vivo</i> tumor initiation and growth after a stable knockdown of <i>ATG5</i>. …”

Clinical outcomes. by Tomohiko Shindo (612852)

“…The average weekly nitroglycerin use (times/week) was decreased from 5.50 to 2.44 in the LIPUS group and from 5.94 to 2.83 in the placebo group. …”

The negative effect of lipid challenge on autophagy inhibits T cell responses by Ignacio Guerrero-Ros (6587345)

“…Furthermore, analysis of T cells from diet-induced obese mice confirms that high lipid load inhibits activation-induced responses in T cells. We have found that autophagy is inhibited in CD4⁺ T cells exposed <i>in vitro</i> or <i>in vivo</i> to lipid stress, which causes decreased autophagosome formation and degradation. …”

Data_Sheet_1_Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain.pdf by Nicolas Dupré (357758)

“…Investigations were based on direction, amplitude, and duration of responses, basal expression, and annotation. Five major points deserve attention; (i) inductions exceeded repressions (60/40%) at both ages, (ii) only 20.3% (393/1938 records) were common to P5 and P10 mice, (iii) at P5, HI effects occurred early and decreased 24 h after insult whereas they were delayed at P10 and increased 24 h after insult, (iv) common responses at P5 and P10 involved inflammation, immunity, apoptosis, and angiogenesis. …”

Table_1_Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain.xlsx by Nicolas Dupré (357758)

“…Investigations were based on direction, amplitude, and duration of responses, basal expression, and annotation. Five major points deserve attention; (i) inductions exceeded repressions (60/40%) at both ages, (ii) only 20.3% (393/1938 records) were common to P5 and P10 mice, (iii) at P5, HI effects occurred early and decreased 24 h after insult whereas they were delayed at P10 and increased 24 h after insult, (iv) common responses at P5 and P10 involved inflammation, immunity, apoptosis, and angiogenesis. …”

Reconstruction of the life history traits in the giant salamander <i>Aviturus exsecratus</i> (Caudata, Cryptobranchidae) from the Paleocene of Mongolia using zygapophyseal skeletoc... by Pavel P. Skutschas (9275804)

“…We found that <i>Aviturus exsecratus</i> had a similar time of the attainment of sexual maturity and decreasing of juvenile growth (5–8 years) and estimated body size at maturity (50–60% of the maximum size) as modern cryptobranchids. …”

Image1_Impact of in Utero Rat Exposure to 17Alpha-Ethinylestradiol or Genistein on Testicular Development and Germ Cell Gene Expression.JPEG by Laetitia L. Lecante (12716315)

“…In addition, transcriptomic studies have demonstrated immediate effects on gene expression in fetal reproductive tissues, However, the immediate molecular effects on the developing germ cells have been poorly investigated. Here, we took advantage of a transgenic rat expressing the green fluorescent protein specifically in germ cells allowing purification of perinatal GFP-positive germ cells. …”

Table1_Impact of in Utero Rat Exposure to 17Alpha-Ethinylestradiol or Genistein on Testicular Development and Germ Cell Gene Expression.DOC by Laetitia L. Lecante (12716315)

“…In addition, transcriptomic studies have demonstrated immediate effects on gene expression in fetal reproductive tissues, However, the immediate molecular effects on the developing germ cells have been poorly investigated. Here, we took advantage of a transgenic rat expressing the green fluorescent protein specifically in germ cells allowing purification of perinatal GFP-positive germ cells. …”

Blocking the C/EBPβ-Thr217 phosphorylation ameliorates the induction of lung fibrosis by Bleomycin. by Martina Buck (82941)

“…Treatment of C/EBPβ^wt mice with the C/EBPβ peptide (on day-2 and day-6) after Bleomycin treatment ameliorated the lung fibrosis at day-21 (mean fibrosis score: 2.0+/−0.7; <i>n</i>: 5; <i>P</i> = 0.048). <b>B.</b> Representative Sirius red immunohistochemistry for collagen by light microscopy (in red) (L panels) and with a polarized light (R panels). …”

AL-9 inhibits PI4KIIIα in HCV-replicating cells. by Annalisa Bianco (178719)

“…PI4KIIIα, associated with the HCV-associated membranous web is inhibited by AL-9. The decrease of PI4P is not due to inhibition of the HCV replication indicated by unchanged NS5A expression and localization (lower panel). …”

Distinct decoy effects in two groups of subjects identified by clustering based on all decoy-effect indices. by Mehran Spitmaan (7495811)

“…Subjects in the first group (N = 72) selected the target with a probability larger than 0.5 for all decoy types (increased risk aversion), whereas subjects in the second group (N = 58) selected the target with a probability smaller than 0.5 (decreased risk aversion). …”

Effect of sagopilone (SAG) on cell proliferation, tubulin cytoskeleton, cell cycle and apoptosis of lung cancer cells. by Sebastian Winsel (222664)

“…A549 cells were incubated for 72 hrs with vehicle, or 2.5 nM, 5 nM, 10 nM, 40 nM, or 100 nM SAG. …”

Data_Sheet_1_Integrated Metabolome and Transcriptome Analysis of Fruit Flavor and Carotenoids Biosynthesis Differences Between Mature-Green and Tree-Ripe of cv. “Golden Phoenix” Ma... by Lei Peng (260321)

“…The analysis of carotenoid contents identified 68 carotenoids and we report for the first-time significant contents of zeaxanthin palmitate and (E/Z)-phytoene in mango fruits. α-carotene was a further major contributor to carotene contents with lesser contributions from 5,6epoxy-lutein-caprate-palmitate, β-carotene, lutein oleate, and β-cryptoxanthin. …”

Evolutionary and Biotechnological Implications of Robust Hydrogenase Activity in Halophilic Strains of Tetraselmis by Sarah D'Adamo (511712)

“…The influence of salinity (3.5%, 5.5% and 7.0% w/v NaCl) on H₂ production was examined during anoxic acclimation, with the greatest in vivo H₂-production rates observed at 7.0% NaCl. …”