Quercetin Represses Apolipoprotein B Expression by Inhibiting the Transcriptional Activity of C/EBPβ by Makoto Shimizu (29536)

“…On the exposure of Caco-2 cells to quercetin, both mRNA and protein levels of apoB were decreased. Promoter analysis of the human <i>apoB</i> revealed that quercetin response element is localized at the 5′-proximal promoter region, which contains a conserved CCAAT enhancer-binding protein (C/EBP)-response element. …”

Hematopoietic stem cell transplantation activity in Mexico during the COVID19 pandemic: on the way to recovery by Andrés Gómez-De León (14259854)

“…<p>To analyze the number of HSCTs performed in 2019 vs. 2020 and report the status of transplant centers (TCs) during and a year after the COVID-19 pandemic.</p> <p>We performed a comprehensive cross-sectional nationwide study including active TCs interrogating HSCT activity from 2019 through September 2021. …”

FGF-2 Deficiency Does Not Influence FGF Ligand and Receptor Expression during Development of the Nigrostriatal System by Andreas Ratzka (183750)

“…Moreover, 3 developmentally down-regulated FGFs (FGF-8b, FGF-15, FGF-17a) were functionally characterized by plasmid-based over-expression in dissociated E11.5 VM cell cultures, however, such a continuous exposure had no influence on the yield of dopaminergic neurons <em>in vitro</em>.…”

hTTR levels in serum and stomach. by Elena Panayiotou (3925415)

“…<p>hTTR immunoblotting exhibiting a single band at 14KDa (<i>A</i>). hTTR levels measured via immunoblotting in serum of V30M and V30M C1q KO animals of all three age groups indicating higher hTTR in the V30M mice and a gradual decrease in the amount of hTTR present as the animals age (<i>B</i>). hTTR levels measured via immunoblotting in stomach tissue of the V30M and V30M C1q KO animals exhibit a severe decrease in the second age group (<i>C</i>). …”

Data de- and re-dimensioning for optimized brokering access by Daniel R. Fuka (558589)

DataSheet_1_Treatment Interruptions During Stereotactic Body Radiotherapy for Prostate Cancer.docx by Abigail N. Pepin (11966438)

“…Median length of time to complete treatment was 11 days (range 5–155 days). In patients who experienced a delay, nearly half (45.5%) experienced only a one-day delay. …”

Examination of known somatic cell B-Myb target gene expression patterns following knockdown of B-Myb in ESCs. by Ming Zhan (27937)

“…B) RNA (left) and protein (right) analysis of the B-MYB target gene Polo-like kinase 1 (Plk1) following Bγ-Myb KD with shRNA1 and shRNA5. The effects of B-MYB KD on Plk1 RNA were transient; however, the loss of RNA led to a significant and sustained decrease in its protein abundance. …”

Stability of beta-titanium T-loop springs preactivated by gradual curvature by Sergei Godeiro Fernandes Rabelo Caldas (4791744)

“…The other eight groups were tested after 24, 48 and 72 hours, 1, 2, 4, 8 and 12 weeks, respectively. Using a moment transducer coupled to a digital extensometer indicator adapted to a universal testing machine, the amount of horizontal force, moment and moment-to-force ratios were recorded at every 0.5 mm of deactivation from 5 mm of the initial activation, in an interbracket distance of 23 mm. …”

Image2_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Regulation of cardiac transcription factors in liver stem cells co-cultured with cardiomyocytes after minimizing CAMTA1 expression. by Barbara Muller-Borer (159061)

“…The graphs illustrate expression of the transcription factors CAMTA1, CAMTA2, Nk×2.5, Myocardin, cTnT and BetaMHC. A significant decrease in the expression of transcription factors Nkx2.5, Myocardin, cTnT and BetaMHC were measured when CAMTA1 expression was minimized. …”

Buffer Zones for 2,4-D Applications Nearby Tobacco Fields by Matheus Machado Noguera (13022509)

“…Drifted herbicide was collected using tobacco plants placed at various points (-50 up to 400 meters from application zone), following three schemes: a) 0 to 0.5 hours after application (HAT); b) 0 to 24 HAT; and c) 0.5 to 24 HAT. …”

Image1_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Evaluation of paralysis time and animal behavior in the open field. by Sunamita de Carvalho Lima (5598089)

“…The last bar in panel A, indicated by the 24 h in the open box, refers to the <i>ip</i> administration of same dose of crotamine (7.5 μg/animal or 0.3 mg/kg BW) in the same animal 24 h after first crotamine administration, showing a significant decrease in the time for paralysis onset compared to the first administration of crotamine in naïve animal, a day before. …”

Systemic status of WT and miR-150 null mutant (miR-150^-/-) mice with normal chow diet or HFD. by Liheng Shi (144105)

“…There is no statistical interaction between miR-150 null mutation and HFD regimen (2-way ANOVA). n = 5 for each group. (C) Wild type mice fed with HFD have a significant decrease of miR-150 expression compared to mice fed with normal diet (Normal; student’s <i>t</i>-test). …”

Non-parametric regression of the number of basic cognitive units (BCU) on age. by Raúl de la Fuente-Fernández (42989)

“…</p> <p>Data points were directly derived from the <i>z</i>-scores associated with the corresponding Alzheimer's incidence rates, using the equation: BCU|age = 0.5−0.1× <i>z</i>-score, where the threshold (<i>c</i>) is 0.5, and the standard deviation (SD) is 0.1 (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000052#s2" target="_blank">Methods</a>).…”

Competition between filopodial tension and surface tension in the 2D filopodial tension model. by Julio M. Belmonte (204008)

“…<p>(<b>A</b>) The elongation time (τ) till the <b>tissue’s</b> inverse aspect ratio decreases to 0.5 as a function of the filopodial tension (λ_force) of the cells for different surface tensions (γ). …”

Conditional knockout of <i>Ezh2</i> gene in murine hearts caused perinatal lethality. by Li Chen (5749)

“…Semi-quantitative RT-PCR with two different numbers of amplification cycles (30 and 35) was performed on RNA samples purified from WT hearts of E9.5, E10.5, and E11.5. 1 µl or 0.5 µl cDNA from reverse transcription reaction was used for detection of Ezh2 or GAPDH (as a control), respectively. …”

T-helper cell pathway diagram. by Josephine S. D’Alessandro (814578)

“…Gray lines indicate members of a group. APCs, antigen-presenting cells; CXCR1, chemokine (C-X-C motif) receptor 1; CXCR3, chemokine (C-X-C motif) receptor 3; CXCR5, chemokine (C-X-C motif) receptor 5; CXCL10, chemokine (C-X-C motif) ligand 10; GA, glatiramer acetate; HLADMA, major histocompatibility complex class II, DM alpha; HLADMB, major histocompatibility complex class II, DM beta; HLADQB1, major histocompatibility complex class II, DQ beta 1; ICOSLG, inducible T-cell costimulatory ligand; IL-4, interleukin-4; MHC class II, major histocompatibility complex class II; LTB, lymphotoxin beta (tumor necrosis factor superfamily, member 3); MYD, myeloid differentiation primary response protein; S100A10, S100 calcium-binding protein A10; STAT, signal transducer and activator of transcription; TCR, T-cell receptor; Th, T-helper.…”

Fig 2 - by G. Cennamo (11785349)

“…The patient shows a focal reduction in GCC and RNFL (B4, B5) at baseline, a slight decrease in GCC (C4) and an absence of changes in RNFL (C5) at 48 hours after surgery. …”

Highly Sensitive and Selective Electrochemical Sensor via Cu-BTC/Au@Cu-BTC Modified Screen-Printed Electrode for the Detection of Chemical Agents by Xiaosen Li (6263651)

“…Herein, we developed a highly sensitive and selective glove-based electrochemical sensor based on a metal–organic-framework-modified screen printed electrode (SPE) for chemical agent marker detection. …”