PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling by Jian Song (4232)

“…P-STAT3 was down-regulated after 5-aza treatment. Overexpressing FN1 decreased PTPRM levels (<i>p</i> < 0.001), knockdown of FN1 decreased PTPRM methylation and inhibited STAT3 phosphorylation. …”

Widespread Neogene volcanism on Central Kerguelen Plateau, Southern Indian Ocean by R. A. Duncan (3136812)

“…These are probably related to hotspot activity now underlying the Heard Island area. We see evidence of much younger activity (5 Ma to present) in volcanic fields to the north of, and up to 300 km NE of, Heard Island. …”

Factors associated with sexual satisfaction of men with spinal cord injury by Fernando Luiz Cardoso (4619239)

“…The programs SPSS (version 20.0) and R (version 3.3.1) were used for statistical analysis, respecting the range of 5%. Initially, we used the descriptive analysis through absolute and relative frequencies. …”

Combined <em>In Silico</em> and <em>In Vivo</em> Analyses Reveal Role of <em>Hes1</em> in Taste Cell Differentiation by Masato S. Ota (265717)

“…Based on this analysis, we identified <em>Hes1</em> as a likely common regulatory factor, and examined its function <em>in vivo</em>. …”

Response of adult dragonflies to artificial prey of different size and colour by Tammy M. Duong (4182808)

“…Therefore, it is likely that their behaviour also shapes the nature of anti-predator traits. In this study, we evaluated the rates of attack of a community (13 species) of mature adult dragonflies (Odonata) on artificial prey of varying size (2.5–31 mm lengthwise) and colour pattern (black, black/yellow striped). …”

<b>Ontogeny of energy use in harvester ant colonies, and the cost of rearing brood </b> by Xiaohui Guo (9669860)

“…In multiple social insect taxa, colony metabolic rate scales hypometrically across species or populations at the same developmental stage, but metabolic patterns during ontogeny have not been examined for any social insect species. We performed the first ontogenetic study of social metabolic scaling in harvester ant colonies (<i>Pogonomyrmex californicus</i>) over 3.5 years as they grew from 52±12 to 767±380 workers. …”

DataSheet_1_Changes of androgen and corticosterone metabolites excretion and conversion in cystic fibrosis.pdf by Rafał Podgórski (11606097)

“…We have also found the increased conversion activity of 11-oxyganated steroids by 5a-reductase in backdoor pathway. …”

Supplementary Material for: Critical Analysis of a Series of Early Inguinal Ureterostomies: Are They Useful and How Well Are They Tolerated by Bouty A. (3419066)

“…We also performed a survey of parents to evaluate their acceptance of diversion. …”

DataSheet_1_Low-Salt Diet Attenuates B-Cell- and Myeloid-Cell-Driven Experimental Arthritides by Affecting Innate as Well as Adaptive Immune Mechanisms.docx by Bettina Sehnert (23407)

“…We did not observe an aggravation of arthritis with HS diet compared to RS diet. …”

PPARγ2-depenent luciferase reporter assay was performed, and mRNA expressions of adipogenic genes in FL83B cell line were assessed by RT-PCR. by Chung-Hwa Park (3637009)

Supplementary Material for: MicroRNA Expression Profiles as Diagnostic and Prognostic Biomarkers of Perinatal Asphyxia and Hypoxic-Ischaemic Encephalopathy by Winkler I. (11992004)

“…Asphyxiated neonates requiring therapeutic hypothermia had significantly increased expression of hsa-miR-30e-5p and significantly decreased expression of hsa-miR-142-3p, hsa-miR-338-3p, hsa-miR-34b-3p, hsa-miR-497-5p, and hsa-miR-98-5p at the time of admission to the NICU. …”

TGF-β1 Exerts Opposing Effects on Grass Carp Leukocytes: Implication in Teleost Immunity, Receptor Signaling and Potential Self-Regulatory Mechanisms by Mu Yang (170922)

“…It is consistent with the observation that TGF-β1 decreased the number of ALK5⁺ leukocytes in PBL and HKL, revealing a negative regulation of TGF-β1 signaling at the receptor level. …”

DataSheet_1_Establishment of Reference Intervals for Thyroid-Associated Hormones Using refineR Algorithm in Chinese Population at High-Altitude Areas.docx by Chaochao Ma (11825525)

“…The RIs for FT3 at Nyingchi, Shigatse/Lhasa, and Ali in females were 4.09–4.98, 4.31–5.45, and 4.82–5.58 pmol/L, while in males, the values were 4.82–5.41, 4.88–5.95, and 5.26–6.06 pmol/L, respectively. …”

Surface hydrophobicity and positively charge on the prM proteins of MR766 and MR/PR(prM). by Eri Nakayama (150555)

“…(B) Patch analysis shows that the pr protein of PRVABC59 has an additional hydrophobic patch due to the A26P and V31M substitutions (Patch 1, 50Ų) and an enlarged hydrophobic patch (50 to 90Ų) due to the H35Y substitution (Patch 2) (dashed circles). …”

Relationship between light-evoked responses and duration of light pulses. by Adriana Galvan (115777)

“…<p>A-D: Examples of peristimulus time histograms and raster diagrams of the response of the same VL neuron to light pulses of decreasing duration. …”

Effect of Salmonella enterica serovar Enteritidis infection on egg production and immune response of the laying duck by Guohong Chen (5590448)

“…Laying rate and egg quality are also decreased after SE infection (<i>P</i><0.05). We further show that SE readily colonizes the stroma, small follicle, isthmus, and vagina in the reproductive tracts of susceptible ducks. …”

Model for grapevine bud cold hardiness and budbreak response: Data files by Amaya Atucha (20927132)

“…Recent studies demonstrate freezing temperatures promote chill accumulation and cold hardiness influences time to budbreak—the phenotype used for dormancy evaluations. Here we evaluated bud cold hardiness and budbreak responses of grapevines (<i>Vitis </i>hybrids) throughout chill accumulation under three treatments: constant (5 °C), fluctuating (−3.5 to 6.5 °C daily), and field conditions (Madison, Wisconsin, USA). …”

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against <i>Toxoplasma gondii</i> by Elizabeth M. Selleck (407365)

“…Virulent strains of <i>T. gondii</i> avoided recruitment of Gbp1 to the parasitophorous vacuole in a strain-dependent manner that was mediated by the parasite virulence factors ROP18, an active serine/threonine kinase, and the pseudokinase ROP5. Increased recruitment of Gbp1 to Δ<i>rop18</i> or Δ<i>rop5</i> parasites was associated with clearance in IFN-γ-activated macrophages <i>in vitro</i>, a process dependent on the autophagy protein Atg5. …”

Lake sediment record of eolian activity on the eastern Tibetan Plateau since 15 cal ka BP by Xiaohuan Hou (19665160)

“…However, after 3.5 ka a sustained intensification of eolian activity occurred in the Gahai area, which was linked to decreasing vegetation cover, reduced regional humidity, and growing human impacts, especially in the eastern plateau, in southern Gansu. …”

Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in <em>Caenorhabditis elegans</em> Elongator Mutants by Changchun Chen (139128)

“…However, how Elongator functions in metazoans, and how the human mutations affect neural functions is incompletely understood. Here we show that in <em>Caenorhabditis elegans</em>, ELPC-1 and ELPC-3, components of the Elongator complex, are required for the formation of the 5-carbamoylmethyl and 5-methylcarboxymethyl side chains of wobble uridines in tRNA. …”